Issue 6, 2016
From the journal:

Molecular BioSystems

Understanding the chemically-reactive proteome

Lyn H. Jonesa  

a Worldwide Medicinal Chemistry, Pfizer, 610 Main Street, Cambridge MA, USA
E-mail: lyn.jones@pfizer.com

Abstract

The reactivity of amino acid residues in proteins is context-dependent and difficult to predict. Chemical biology can be used to understand the chemical modifications of proteins to help elucidate the nature of the reactive proteome. The resulting insights can be applied to pharmacoproteomics, target identification and molecular pathology.

Graphical abstract: Understanding the chemically-reactive proteome

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C5MB00760G
Article type
Opinion
Submitted
07 nov 2015
Accepted
22 dec 2015
First published
22 dec 2015

Mol. BioSyst., 2016,12, 1728-1730

Author version available

Download author version (PDF)

Permissions

Request permissions

Understanding the chemically-reactive proteome

L. H. Jones, Mol. BioSyst., 2016, 12, 1728 DOI: 10.1039/C5MB00760G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements