Issue 73, 2015

Amorphous metal–organic frameworks for drug delivery

Abstract

We report the encapsulation of the hydrophilic model molecule calcein in the Zr-based MOF UiO-66, followed by amorphization of the framework by ball-milling. We show controlled release of calcein over more than 30 days, compared with the 2 day release period from crystalline UiO-66.

Graphical abstract: Amorphous metal–organic frameworks for drug delivery

Supplementary files

Article information

Article type
Communication
Submitted
25 jún 2015
Accepted
21 júl 2015
First published
21 júl 2015

Chem. Commun., 2015,51, 13878-13881

Author version available

Amorphous metal–organic frameworks for drug delivery

C. Orellana-Tavra, E. F. Baxter, T. Tian, T. D. Bennett, N. K. H. Slater, A. K. Cheetham and D. Fairen-Jimenez, Chem. Commun., 2015, 51, 13878 DOI: 10.1039/C5CC05237H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements