Issue 19, 2013
From the journal:

Chemical Communications

1,3,5-Trisubstituted benzenes as fluorescent photoaffinity probes for human carbonic anhydrase II capture†

Partha Sarathi Addy,a   Baisakhee Saha,b   N. D. Pradeep Singh,a   Amit K. Das,*b   Jacob T. Bush,c   Clarisse Lejeune,c   Christopher J. Schofield*c  and  Amit Basak*a  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, India
E-mail: absk@chem.iitkgp.ernet.in
Fax: +91 3222 282552
Tel: +91 3222 283300

b Department of Biotechnology, Indian Institute of Technology, Kharagpur 721302, India

c Department of Chemistry, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, UK

Abstract

The synthesis of small molecule based 1,3,5-trisubstituted benzenes for photo-mediated capture of human carbonic anhydrase II with visualisation by fluorescence is described.

Graphical abstract: 1,3,5-Trisubstituted benzenes as fluorescent photoaffinity probes for human carbonic anhydrase II capture

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Article information

DOI
https://doi.org/10.1039/C3CC38251F
Article type
Communication
Submitted
15 nov 2012
Accepted
17 jan 2013
First published
17 jan 2013

Chem. Commun., 2013,49, 1930-1932

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1,3,5-Trisubstituted benzenes as fluorescent photoaffinity probes for human carbonic anhydrase II capture

P. Sarathi Addy, B. Saha, N. D. Pradeep Singh, A. K. Das, J. T. Bush, C. Lejeune, C. J. Schofield and A. Basak, Chem. Commun., 2013, 49, 1930 DOI: 10.1039/C3CC38251F

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