Issue 19, 2023

Implantable microfluidics: methods and applications

Abstract

Implantable microfluidics involves integrating microfluidic functionalities into implantable devices, such as medical implants or bioelectronic devices, revolutionizing healthcare by enabling personalized and precise diagnostics, targeted drug delivery, and regeneration of targeted tissues or organs. The impact of implantable microfluidics depends heavily on advancements in both methods and applications. Despite significant progress in the past two decades, continuous advancements are still required in fluidic control and manipulation, device miniaturization and integration, biosafety considerations, as well as the development of various application scenarios to address a wide range of healthcare issues. In this review, we discuss advancements in implantable microfluidics, focusing on methods and applications. Regarding methods, we discuss progress made in fluid manipulation, device fabrication, and biosafety considerations in implantable microfluidics. In terms of applications, we review advancements in using implantable microfluidics for drug delivery, diagnostics, tissue engineering, and energy harvesting. The purpose of this review is to expand research ideas for the development of novel implantable microfluidic devices for various healthcare applications.

Graphical abstract: Implantable microfluidics: methods and applications

Article information

Article type
Tutorial Review
Submitted
15 jún 2023
Accepted
30 aug 2023
First published
07 sep 2023

Analyst, 2023,148, 4637-4654

Implantable microfluidics: methods and applications

T. Luo, L. Zheng, D. Chen, C. Zhang, S. Liu, C. Jiang, Y. Xie, D. Du and W. Zhou, Analyst, 2023, 148, 4637 DOI: 10.1039/D3AN00981E

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