A high-frequency QCM biosensing platform for label-free detection of the SARS-CoV-2 spike receptor-binding domain: an aptasensor and an immunosensor

Qingqing Zhang; Shuping Liu; Xiaohua Zhang; Cuicui Du; Shihui Si; Jinhua Chen

doi:10.1039/D3AN00008G

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A high-frequency QCM biosensing platform for label-free detection of the SARS-CoV-2 spike receptor-binding domain: an aptasensor and an immunosensor†

Qingqing Zhang,‡^a Shuping Liu,‡^b Xiaohua Zhang,

^a Cuicui Du,^a Shihui Si*^b and Jinhua Chen

*^a

Author affiliations

* Corresponding authors

^a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China
E-mail: chenjinhua@hnu.edu.cn

^b College of Chemistry and Chemical Engineering, Central South University, Changsha, P. R. China
E-mail: sishihui@163.com
Fax: +86-731-88821848
Tel: +86-731-88821848

Abstract

Herein, high-frequency quartz crystal microbalance biosensing platforms were constructed using an aptamer and antibody as bioreceptors for fast and label-free detection of the SARS-CoV-2 RBD.

This article is part of the themed collection: Sensors for Health

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Article information

DOI: https://doi.org/10.1039/D3AN00008G
Article type: Communication
Submitted: 03 jan 2023
Accepted: 16 jan 2023
First published: 20 jan 2023

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Analyst, 2023,148, 719-723

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A high-frequency QCM biosensing platform for label-free detection of the SARS-CoV-2 spike receptor-binding domain: an aptasensor and an immunosensor

Q. Zhang, S. Liu, X. Zhang, C. Du, S. Si and J. Chen, Analyst, 2023, 148, 719 DOI: 10.1039/D3AN00008G

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A high-frequency QCM biosensing platform for label-free detection of the SARS-CoV-2 spike receptor-binding domain: an aptasensor and an immunosensor†

Abstract

Supplementary files

Article information

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A high-frequency QCM biosensing platform for label-free detection of the SARS-CoV-2 spike receptor-binding domain: an aptasensor and an immunosensor

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