Issue 8, 2022

Visible-light-promoted radical amidoarylation of arylacrylamides towards amidated oxindoles

Abstract

A visible-light-promoted intermolecular radical amidation/cyclization of arylacrylamides was realized by using N-aminopyridinium salts as the source of amidyl radicals. The reaction exhibits a broad scope and good functional group tolerance, and a variety of amide-tethered-oxindoles were prepared in this way in moderate to good yields.

Graphical abstract: Visible-light-promoted radical amidoarylation of arylacrylamides towards amidated oxindoles

Supplementary files

Article information

Article type
Research Article
Submitted
24 jan 2022
Accepted
25 feb 2022
First published
28 feb 2022

Org. Chem. Front., 2022,9, 2164-2168

Visible-light-promoted radical amidoarylation of arylacrylamides towards amidated oxindoles

Y. Wang, W. Lin, H. Liu and W. Yu, Org. Chem. Front., 2022, 9, 2164 DOI: 10.1039/D2QO00127F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements