Issue 47, 2021

Recent developments in the kinetics of ruptures of giant vesicles under constant tension

Abstract

External tension in membranes plays a vital role in numerous physiological and physicochemical phenomena. In this review, recent developments in the constant electric- and mechanical-tension-induced rupture of giant unilamellar vesicles (GUVs) are considered. We summarize the results relating to the kinetics of GUV rupture as a function of membrane surface charge, ions in the bathing solution, lipid composition, cholesterol content in the membrane, and osmotic pressure. The mechanical stability and line tension of the membrane under these conditions are discussed. The membrane tension due to osmotic pressure and the critical tension of rupture for various membrane compositions are also discussed. The results and their analysis provide a biophysical description of the kinetics of rupture, along with insight into biological processes. Future directions and possible developments in this research area are included.

Graphical abstract: Recent developments in the kinetics of ruptures of giant vesicles under constant tension

Article information

Article type
Review Article
Submitted
15 jún 2021
Accepted
17 aug 2021
First published
02 sep 2021
This article is Open Access
Creative Commons BY license

RSC Adv., 2021,11, 29598-29619

Recent developments in the kinetics of ruptures of giant vesicles under constant tension

M. A. S. Karal, Md. K. Ahamed, M. Ahmed and Z. B. Mahbub, RSC Adv., 2021, 11, 29598 DOI: 10.1039/D1RA04647K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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