Issue 57, 2019

Organotin(iv) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring

Abstract

A dual-emissive fluorescent probe enabling dynamic changes in nuclear local microviscosity monitoring was developed. The new sensing scenario involves probe subcellular localization redistribution, allowing a quantitative analysis of the local microviscosity related to nuclear damage in the presence of agents perturbing the nuclear morphology. With the aid of an organotin(IV) in situ formed complex we propose a different scenario of bioanalytical applications through confocal microscopy.

Graphical abstract: Organotin(iv) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring

Supplementary files

Article information

Article type
Communication
Submitted
30 máj 2019
Accepted
20 jún 2019
First published
20 jún 2019

Chem. Commun., 2019,55, 8246-8249

Organotin(IV) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring

J. Bernal-Escalante, A. López-Vázquez, D. Araiza-Olivera and A. Jiménez-Sánchez, Chem. Commun., 2019, 55, 8246 DOI: 10.1039/C9CC04179F

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