Issue 12, 2019
From the journal:

Chemical Communications

Real-time visualization of autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe†

Peng Ning,‡a   Liling Hou,‡a   Yan Feng, ORCID logo *a   Guoyong Xu,b   Yuyuan Bai,a   Haizhu Yua  and  Xiangming Meng ORCID logo *ab  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Center for Atomic Engineering of Advanced Materials, and Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, Anhui University, Hefei, Anhui 230601, China
E-mail: fy70@163.com, mengxm@ahu.edu.cn
Fax: +86 551 63861467
Tel: +86 551 63861467

b Institute of Physical Science and Information Technology, Anhui University, Hefei 230601, P. R. China

Abstract

A benzimidazole-decorated two-photon fluorescent probe (Lyso-MPCB) based on the p-methoxyphenylacetylene-substituted carbazole was developed for detecting lysosomal pH with a double-channel signal, which can be used to visualize autophagy by real-time imaging the fluctuation of the pH in the lysosomes.

Graphical abstract: Real-time visualization of autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8CC09517E
Article type
Communication
Submitted
30 nov 2018
Accepted
10 jan 2019
First published
11 jan 2019

Chem. Commun., 2019,55, 1782-1785

Permissions

Request permissions

Real-time visualization of autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe

P. Ning, L. Hou, Y. Feng, G. Xu, Y. Bai, H. Yu and X. Meng, Chem. Commun., 2019, 55, 1782 DOI: 10.1039/C8CC09517E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements