Issue 47, 2018

Silver-mediated oxidative functionalization of alkylsilanes

Abstract

A general approach to the functionalization of aliphatic C–Si bonds in the presence of silver salts and oxidants has been reported. This strategy encompasses a range of valuable C–Si transformations, including the direct conversions of a C–Si bond to C–OCF3, C–OBz, C–OCOCF3, C–SCF3, C–SCN, and C–N3 bonds. Among them, trifluoromethoxylation of alkylsilanes is reported for the first time. In addition, mechanistic studies indicate that this reaction may proceed through a radical mechanism.

Graphical abstract: Silver-mediated oxidative functionalization of alkylsilanes

Supplementary files

Article information

Article type
Edge Article
Submitted
21 aug 2018
Accepted
22 sep 2018
First published
24 sep 2018
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY-NC license

Chem. Sci., 2018,9, 8836-8841

Silver-mediated oxidative functionalization of alkylsilanes

F. Wang, P. Xu, F. Cong and P. Tang, Chem. Sci., 2018, 9, 8836 DOI: 10.1039/C8SC03730B

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