Issue 17, 2018

Bromide-catalyzed electrochemical trifluoromethylation/cyclization of N-arylacrylamides with low catalyst loading

Abstract

The electrochemical trifluoromethylarylation of N-arylacrylamides catalyzed by bromide is described. The synthetic utility of this methodology is demonstrated by transition metal-free and external oxidant-free conditions, and low catalyst loading.

Graphical abstract: Bromide-catalyzed electrochemical trifluoromethylation/cyclization of N-arylacrylamides with low catalyst loading

Supplementary files

Article information

Article type
Research Article
Submitted
30 jún 2018
Accepted
27 júl 2018
First published
30 júl 2018

Org. Chem. Front., 2018,5, 2573-2577

Bromide-catalyzed electrochemical trifluoromethylation/cyclization of N-arylacrylamides with low catalyst loading

Y. Jiang, G. Dou, K. Xu and C. Zeng, Org. Chem. Front., 2018, 5, 2573 DOI: 10.1039/C8QO00645H

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