Aromatically functionalized pseudo-crown ethers with unusual solvent response and enhanced binding properties†
Abstract
Conformational flexibility in the host's structure is often considered detrimental to its binding. Flexible pseudo-crown ethers with aromatic donor/acceptor groups at the chain ends, however, displayed enhanced binding affinity and selectivity, particularly when the direct binding interactions were compromised by unfavorable solvents.
- This article is part of the themed collection: Supramolecular chemistry in OBC