Issue 13, 2016
From the journal:

Analyst

Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors†

Gunnar Dunér,ab   Henrik Anderson,bc   Zhichao Pei,b   Björn Ingemarsson,b   Teodor Aastrupb  and  Olof Ramström*a  

* Corresponding authors

a KTH – Royal Institute of Technology, Department of Chemistry, Teknikringen 30, S-10044 Stockholm, Sweden
E-mail: ramstrom@kth.se

b Attana AB, Björnnäsvägen 21, S-11419 Stockholm, Sweden

c Uppsala University, Ångström Laboratory, Solid State Electronics, P.O. Box 534, S-75121 Uppsala, Sweden

Abstract

The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment. The poly(acrylic acid) sensors showed a dramatic increase in signal response with more than ten times higher signal than the carboxyl-terminated self-assembled monolayer surface.

Graphical abstract: Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6AN00735J
Article type
Communication
Submitted
29 mar 2016
Accepted
11 máj 2016
First published
12 máj 2016
This article is Open Access
Creative Commons BY-NC license

Analyst, 2016,141, 3993-3996

Permissions

Request permissions

Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

G. Dunér, H. Anderson, Z. Pei, B. Ingemarsson, T. Aastrup and O. Ramström, Analyst, 2016, 141, 3993 DOI: 10.1039/C6AN00735J

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements