Issue 31, 2011

New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

Abstract

A new method for selective cleavage of 2-naphthylmethyl (NAP) ether utilizing 10–20 molar excess of HF/pyridine in toluene was revealed and strategically applied to a divergent approach towards generation of a high-mannose type oligosaccharide library.

Graphical abstract: New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

Supplementary files

Article information

Article type
Communication
Submitted
02 jún 2011
Accepted
22 jún 2011
First published
07 júl 2011

Chem. Commun., 2011,47, 8952-8954

New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library

Y. Li, B. Roy and X. Liu, Chem. Commun., 2011, 47, 8952 DOI: 10.1039/C1CC13264D

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