Issue 10, 2008
From the journal:

Chemical Communications

Hydrolase-catalyzed biotransformations in deep eutectic solvents†

Johnathan T. Gorke,ab   Friedrich Srienc*ab  and  Romas J. Kazlauskas*bc  

* Corresponding authors

a Department of Chemical Engineering and Materials Science, University of Minnesota, 151 Amundson Hall, 421 Washington Ave. SE, Minneapolis, USA
E-mail: srienc@umn.edu
Fax: +1 612 626 7246
Tel: +1 612 625 6362

b BioTechnology Institute, 240 Gortner Lab, University of Minnesota, 1479 Gortner Ave., Saint Paul, USA
Fax: +1 612 625 1700
Tel: +1 612 624 9776

c Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, 140 Gortner Lab, 1479 Gortner Ave., Saint Paul, USA
E-mail: rjk@umn.edu
Fax: +1 612 625 5780
Tel: +1 612 624 5904

Abstract

Hydrolases show good catalytic activity in deep eutectic solvents, despite the presence of urea, which can denature enzymes, or alcohols, which can interfere with hydrolase-catalyzed reactions.

Graphical abstract: Hydrolase-catalyzed biotransformations in deep eutectic solvents

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Article information

DOI
https://doi.org/10.1039/B716317G
Article type
Communication
Submitted
07 nov 2007
Accepted
14 jan 2008
First published
31 jan 2008

Chem. Commun., 2008, 1235-1237

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Hydrolase-catalyzed biotransformations in deep eutectic solvents

J. T. Gorke, F. Srienc and R. J. Kazlauskas, Chem. Commun., 2008, 1235 DOI: 10.1039/B716317G

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