Issue 36, 2024

A review of organic small-molecule fluorescent probes for the gallium(iii) ion

Abstract

Gallium metal and gallium compounds play significant roles in industry and medicine; however, their pollution and residue can pose potential risks to plants, animals and human health. Moreover, accurately detecting Ga3+ during tumor treatment holds great clinical significance. Therefore, it is crucial to reliably determine the content of Ga3+ in environmental and biological samples. Organic small-molecule fluorescent probe technology offers high selectivity and sensitivity, rapid detection speed, and non-destructive in situ bioimaging capabilities, making it an ideal approach for Ga3+ detection. The numerous reported probes for detecting Ga3+ highlight the immense application potential of fluorescent probes in this field. However, due to limited development of Ga3+-specific fluorescent probes thus far, several challenges associated with their design and development remain. This paper presents a comprehensive overview of the performance achieved by Ga3+ fluorescent probes, while addressing existing issues and proposing corresponding solutions. Additionally, future directions for developing highly efficient Ga3+ fluorescent probes are outlined as valuable guidance.

Graphical abstract: A review of organic small-molecule fluorescent probes for the gallium(iii) ion

Supplementary files

Article information

Article type
Critical Review
Submitted
19 júl 2024
Accepted
17 aug 2024
First published
19 aug 2024

Anal. Methods, 2024,16, 6119-6133

A review of organic small-molecule fluorescent probes for the gallium(III) ion

L. Yan, X. Xu and K. Bao, Anal. Methods, 2024, 16, 6119 DOI: 10.1039/D4AY01347F

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