Issue 63, 2018
From the journal:

Chemical Communications

Uracil grafted imine-based covalent organic framework for nucleobase recognition†

Sergio Royuela, ORCID logo ab   Eduardo García-Garrido,c   Miguel Martín Arroyo, ORCID logo d   María J. Mancheño, ORCID logo a   María M. Ramos,b   David González-Rodríguez, ORCID logo df   Álvaro Somoza, ORCID logo *c   Félix Zamora ORCID logo *cefg  and  José L. Segura ORCID logo *a  

* Corresponding authors

a Departamento de Química Orgánica I, Facultad de CC. Químicas, Universidad Complutense de Madrid, Madrid 28040, Spain
E-mail: segura@ucm.es

b Departamento de Tecnología Química y Ambiental, Universidad Rey Juan Carlos, Madrid 28933, Spain

c Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA-Nanociencia), Cantoblanco, Madrid E-28049, Spain

d Departamento de Orgánica, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid 28049, Spain

e Departamento de Inorgánica, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid 28049, Spain

f Institute for Advanced Research in Chemical Sciences (IAdChem), Universidad Autónoma de Madrid, 28049 Madrid, Spain

g Condensed Matter Physics Center (IFIMAC), Universidad Autónoma de Madrid, 28049 Madrid, Spain

Abstract

An imine-based covalent organic framework (COF) decorated in its cavities with uracil groups has shown selective recognition towards adenine in water. These results show how the confinement of the base-pair inside the COF's pores allows a remarkable selective recognition in aqueous media.

Graphical abstract: Uracil grafted imine-based covalent organic framework for nucleobase recognition

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Article information

DOI
https://doi.org/10.1039/C8CC04346A
Article type
Communication
Submitted
31 máj 2018
Accepted
13 júl 2018
First published
13 júl 2018

Chem. Commun., 2018,54, 8729-8732

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Uracil grafted imine-based covalent organic framework for nucleobase recognition

S. Royuela, E. García-Garrido, M. Martín Arroyo, M. J. Mancheño, M. M. Ramos, D. González-Rodríguez, Á. Somoza, F. Zamora and J. L. Segura, Chem. Commun., 2018, 54, 8729 DOI: 10.1039/C8CC04346A

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