Issue 2, 2003
From the journal:

Chemical Communications

Crystal engineering of the composition of pharmaceutical phases

R. D. Bailey Walsh,a   M. W. Bradner,a   S. Fleischman,a   L. A. Morales,a   B. Moulton,a   N. Rodríguez-Hornedob  and  M. J. Zaworotko*a  

* Corresponding authors

a Department of Chemistry, University of South Florida, 4202 E Fowler Ave (SCA 400), Tampa, FL, USA
E-mail: xtal@usf.edu
Fax: +1 813-974-3203
Tel: 813-974-4129

b Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA

Abstract

The carboxylic acid–pyridine supramolecular heterosynthon can be exploited to predictably generate binary crystalline phases involving rac-ibuprofen, rac-flurbiprofen or aspirin.

Graphical abstract: Crystal engineering of the composition of pharmaceutical phases

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Article information

DOI
https://doi.org/10.1039/B208574G
Article type
Communication
Submitted
13 sep 2002
Accepted
26 nov 2002
First published
20 dec 2002

Chem. Commun., 2003, 186-187

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Crystal engineering of the composition of pharmaceutical phases

R. D. B. Walsh, M. W. Bradner, S. Fleischman, L. A. Morales, B. Moulton, N. Rodríguez-Hornedo and M. J. Zaworotko, Chem. Commun., 2003, 186 DOI: 10.1039/B208574G

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