Recent advances in MXene nanozyme-based optical and electrochemical biosensors for food safety analysis

Chou-Yi Hsu, Nusiba M. M. Alshik, Irfan Ahmad, Subasini Uthirapathy, Suhas Ballal, Abhayveer Singh, Suman Saini and Kamal Kant Joshi

Nanoscale, 2025, 17, 7697
DOI: 10.1039/D5NR00066A

2D nanozymes: bioinspired innovations for healthcare and environmental applications

Pulakesh Borah, Diksha J. Baruah, Rituparna Duarah and Manash R. Das

Chem. Commun., 2025, 61, 10685
DOI: 10.1039/D5CC00180C

Recent advances in MXene nanozymes: synthesis, surface modifications, catalytic properties, and their emerging roles in biosensing and therapeutic applications

Hatem A. Al-Aoh, Chellasamy Panneerselvam, Asim. M. Alghamdi, Abdulrahman Alasmari and Zuhair M. Mohammedsaleh

Analyst, 2026, 151, 991
DOI: 10.1039/D5AN01137J

Bioactive surface-functionalized MXenes for biomedicine

Ting Li, Weipeng Qiang and Bo Lei

Nanoscale, 2025, 17, 4854
DOI: 10.1039/D4NR04260C

MXene and Xene: promising frontier beyond graphene in tissue engineering and regenerative medicine

Moon Sung Kang, Hee Jeong Jang, Hyo Jung Jo, Iruthayapandi Selestin Raja and Dong-Wook Han

Nanoscale Horiz., 2024, 9, 93
DOI: 10.1039/D3NH00428G

Emerging 2D MXene-conjugated nanoarchitectures for nanozymes: current advances and future frontiers in biochemical sensing technologies

Ramar Rajamanikandan, Kandasamy Sasikumar and Heongkyu Ju

Environ. Sci.: Nano, 2025, 12, 4796
DOI: 10.1039/D5EN00710K

DNA-based FeCuAg nanoclusters with peroxidase-like and GSH depletion activities for toxicity of in vitro cancer cells

Chunying Wei and Lujie Chen

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 317, 124446
DOI: 10.1016/j.saa.2024.124446

MXene‐Based Nanozymes: Current Challenges and Future Prospects

Eleonora Pargoletti and Yury Gogotsi

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202500730

Nanozymes meet hydrogels: Fabrication, progressive applications, and perspectives

Manyan Qiu, Chaoxin Man, Qianyu Zhao, Xinyan Yang, Yu Zhang, Wei Zhang, Xianlong Zhang, Joseph Irudayaraj and Yujun Jiang

Advances in Colloid and Interface Science, 2025, 338, 103404
DOI: 10.1016/j.cis.2025.103404

Advancements in employing two-dimensional nanomaterials for enhancing skin wound healing: a review of current practice

Jiaqi Zhao, Tianjiao Li, Yajuan Yue, Xina Li, Zhongjian Xie, Han Zhang and Xing Tian

J Nanobiotechnol, 2024, 22
DOI: 10.1186/s12951-024-02803-y

MXene‐Based Peroxidase‐Like Nanozymes: Interfacial Effects for Biomedical Applications

Tianye Zhang, Mengtian Lu, Xin Lin, Yue Yang, Hao Gu, Meifei Xu, Yuan Sun and Tiedong Sun

The Chemical Record, 2025, 25
DOI: 10.1002/tcr.202500108

Deep eutectic solvent-delaminated MXene decorated with Co Ni MOF as a co-reactant accelerator for ultrasensitive electrochemiluminescent detection of H2O2 released from cancer cells

Seyyed Mehdi Khoshfetrat and Amirhossein Hatami

Microchemical Journal, 2026, 220, 116602
DOI: 10.1016/j.microc.2025.116602

Nanozyme biosensing for food safety: New perspectives on classification, enzymatic activity, and sensing strategies

Qilin Xu, Yong He and Xiaoli Li

Coordination Chemistry Reviews, 2026, 551, 217464
DOI: 10.1016/j.ccr.2025.217464

Bioactive nanoglass-MXene heterojunction with enzymatic-thermal coupling for MRSA-infected wound therapy

Ting Li, Junping Ma, Yidan Wang, Mi Chen, Qian Huang, Long Zhang and Bo Lei

Adv Compos Hybrid Mater, 2025, 8
DOI: 10.1007/s42114-025-01354-6

MXene: A wonderful nanomaterial in antibacterial

Surong Ye, Huichao Zhang, Huiyan Lai, Jingyu Xu, Ling Yu, Zitong Ye and Luyi Yang

Front. Bioeng. Biotechnol., 2024, 12
DOI: 10.3389/fbioe.2024.1338539

Engineering nanozymes for theranostics in urological cancer

Xiangyu Zhang, Yongnan Jiang, Bin Liu, Xinlu Yu, Bo Jia, Yulong Dong, Xinquan Gu, Jinru Xue, Kelong Fan and Yuhan Zhang

Nano Today, 2026, 66, 102930
DOI: 10.1016/j.nantod.2025.102930

MXene nanoenzymes or the CRISPR/Cas system for dual-mode sensors applications

Huanyu Ren, Lina Zou, Lan Jiang, Ping Zhang, Zheng Li, Huiru Niu, Hao Liao, Xiaojing Zhang, Fei Ren, Shanshan An, Xiuhong Ge, Lang Cheng, Feiyan Yang, Hongzhi Pan, Shengzhong Rong, Dong Chang and Hongkun Ma

Microchemical Journal, 2025, 215, 114377
DOI: 10.1016/j.microc.2025.114377

Recent advances on nanozyme-based electrochemical biosensors for cancer biomarker detection

Annadurai Thamilselvan and Moon Il Kim

TrAC Trends in Analytical Chemistry, 2024, 177, 117815
DOI: 10.1016/j.trac.2024.117815

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee and Dong‐Hyun Kim

Adv Funct Materials, 2025, 35
DOI: 10.1002/adfm.202420870

Review: 2D MXenes for biomedical applications—recent advances, challenges, and future perspectives

Sunil Kumar, Nitu Kumari, Christopher Alma Suranto and Syed Muhammad Zain Mehdi

J Mater Sci, 2025, 60, 18595
DOI: 10.1007/s10853-025-11461-w

Bioactive VS4-based sonosensitizer for robust chemodynamic, sonodynamic and osteogenic therapy of infected bone defects

Yaqi He, Xin Liu, Jie Lei, Liang Ma, Xiaoguang Zhang, Hongchuan Wang, Chunchi Lei, Xiaobo Feng, Cao Yang and Yong Gao

J Nanobiotechnol, 2024, 22
DOI: 10.1186/s12951-023-02283-6

Food Nanozymology: Nanozyme Engineering Toward Future Food

Yuanlong Chi, Hao Cheng, Da‐Wen Sun, Lunjie Huang, Qiang He and Bi Shi

Advanced Materials, 2025, 37
DOI: 10.1002/adma.202505552

Recent Advances in MXene-Based Electrochemical Sensors

Ziyi Zhao, Jiayi Cao, Boyu Zhu, Xinru Li, Lin Zhou and Bin Su

Biosensors, 2025, 15, 107
DOI: 10.3390/bios15020107

Microenvironment‐Adaptive Smart Hydrogel with 2D Vanadium Nitride MXenzyme Rescues Osteoarthritis via Coordinated ROS Scavenging and Hspa5/GPX4 Axis‐Mediated Ferroptosis Suppression

Yanlin Li, Xiaotian Jiang, Jiale Li, Hanwen Gu, Qi Li, Jiaxin Li, Yunqing Ji, Xiang Min, Bin Chen, Qingjia Xu and Junhao Lin

Adv Healthcare Materials, 2026
DOI: 10.1002/adhm.202504967

Emerging reactive oxygen and nitrogen species regulators for biomedical therapy: 2D MXenzymes

Jingjing Si, Haihui Lan, Jessica An, Suxiang Ge, Wanyu Liu, YuMing Zhang, Xiaobo Mao and Weiwei He

Materials Today, 2025, 85, 112
DOI: 10.1016/j.mattod.2025.02.004

Exploring the frontiers of X@MXene nanozymes: Synthesis, enhanced catalytic mechanism, and application in biomedical sensors

Shuangning Zhang, Bingrui Lv, Mengyu Wang, Jingyi Liu, Mengyuan Liu, Jiangshan Chen, Ge Song, Shuya Niu, Yutong Zhu, Si Li and Tingting Jiang

Talanta, 2025, 295, 128293
DOI: 10.1016/j.talanta.2025.128293

Biowaste-Archetyped Hierarchical Calcium Carbonate Nanoreactors Induce Tumor Bioenergetic Crisis and Reverse Cisplatin Resistance via Mitochondrial Metabolic Reprogramming

Shupeng Shi, Haicong Liu, Qingping Peng, Shenao Nan, Shuyan Liu, Linna Wei, Haoyu Wang, Kai Wang, Xiaohong Zhong, Xin Chen and Wenzhe Gao

ACS Appl. Mater. Interfaces, 2026
DOI: 10.1021/acsami.6c01369

Rolling circle amplification and CRISPR/Cas14a with nanozyme for electrochemical detecting miRNA-205 in NPC-derived exosomes

Xueqian Xiao, Ying Lu, Jianxue Zhang, Wei Ni, Junlin Liu, Chaoqing Li, Qunfeng Yao, Yujie Sun, Guo-jun Zhang, Yulin Zhang, Yuqing Qin and Yajuan Zhou

Bioelectrochemistry, 2025, 166, 109046
DOI: 10.1016/j.bioelechem.2025.109046

Indocyanine green (ICG)-loaded Ti3C2Tx MXene/Bletilla striata polysaccharide nanocomposite hydrogel for synergistic photothermal-photodynamic antibacterial therapy and wound healing

Xuechun Wang, Yanxiang Sang, Hongjie Zhang, Benyan Zheng, Bibo Wang, Yuan Hu and Ruiying Wu

International Journal of Biological Macromolecules, 2026, 339, 149645
DOI: 10.1016/j.ijbiomac.2025.149645

MXenes and their applications in electrochemical sensors for pharmaceutical analysis

Amir M. Ashrafi, Milan Sýs, Tong Liu, Michaela Bártová and Jiří Homola

Electrochimica Acta, 2026, 558, 148522
DOI: 10.1016/j.electacta.2026.148522

Harnessing MoS2 nanozymes: Mechanistic insights into enzyme-mimetic catalysis for advanced sensing applications

Dong Peng, Mingming Que, Shanshan Huang, Sijia Wei, Neng Wang, Qifang He, Zhonggao Zhou and Hongdeng Qiu

TrAC Trends in Analytical Chemistry, 2026, 194, 118530
DOI: 10.1016/j.trac.2025.118530