A novel AIE fluorescent probe for the monitoring of aluminum ions in living cells and zebrafish

Yabing Gan, Guoxing Yin, Jianhua Wang and Peng Yin

Analyst, 2022, 147, 2828
DOI: 10.1039/D2AN00543C

A novel cell membrane-targeting fluorescent probe for imaging endogenous/exogenous formaldehyde in live cells and zebrafish

Wenlong Sheng, Xue Zhang, Miaohui Yu, Meng Jin, Ning Li, Chen Sun, Lizhen Wang, Qing Xia, Xiaobin Li, Yun Zhang, Baocun Zhu and Kechun Liu

Analyst, 2021, 146, 7554
DOI: 10.1039/D1AN01669E

Reaction-based fluorescent and chemiluminescent probes for formaldehyde detection and imaging

Shumei Huang, Zejun Li, Minghui Liu, Mengjiao Zhou, Jintao Weng, Yong He, Yin Jiang, Huatang Zhang and Hongyan Sun

Chem. Commun., 2022, 58, 1442
DOI: 10.1039/D1CC05644A

A three-channel fluorescent probe to image mitochondrial stress

Huawei Niu, Jun Tang, Xiaofei Zhu, Zipeng Li, Yongru Zhang, Yong Ye and Yufen Zhao

Chem. Commun., 2020, 56, 7710
DOI: 10.1039/D0CC02668A

Independent bi-reversible reactions and regulable FRET efficiency achieving real-time visualization of Cys metabolizing into SO2

Tao Li, Fangjun Huo, Jianbin Chao and Caixia Yin

Chem. Commun., 2020, 56, 11453
DOI: 10.1039/D0CC04839A

A FRET-based ratiometric fluorescent probe to detect cysteine metabolism in mitochondria

Xiaojing Han, Zhiyao Zhai, Xiaopeng Yang, Di Zhang, Jun Tang, Jianming Zhu, Xiaofei Zhu and Yong Ye

Org. Biomol. Chem., 2020, 18, 1487
DOI: 10.1039/D0OB00002G

A ratiometric fluorescent probe for reversible monitoring of endogenous SO2/formaldehyde in cytoplasm and nucleoli regions and its applications in living mice

Yanyan Ma, Wenjie Gao, Linlin Zhu, Yuping Zhao and Weiying Lin

Analyst, 2020, 145, 1865
DOI: 10.1039/C9AN02454A

A novel fluorescent probe for the detection of sulfur dioxide derivatives and its application in biological imaging

Qing-Qing Yang, Qin-Qin Tian, Nan Ji, Xiao-Hong Duan, Xiao-Hong Zhu, Yan-Li Zhang and Wei He

New J. Chem., 2022, 46, 1483
DOI: 10.1039/D1NJ03184H

Natural flavylium-inspired far-red to NIR-II dyes and their applications as fluorescent probes for biomedical sensing

Yuanqiang Sun, Pengjuan Sun, Zhaohui Li, Lingbo Qu and Wei Guo

Chem. Soc. Rev., 2022, 51, 7170
DOI: 10.1039/D2CS00179A

Rational Construction of a Mitochondria-Targeted Reversible Fluorescent Probe with Intramolecular FRET for Ratiometric Monitoring Sulfur Dioxide and Formaldehyde

Jinxiao Lyu, Chunfei Wang and Xuanjun Zhang

Biosensors, 2022, 12, 715
DOI: 10.3390/bios12090715

Recent Progress in Fluorescent Formaldehyde Detection Using Small Molecule Probes

Jiao-Jiao Zheng, Wen-Cai Liu, Feng-Niu Lu, Ying Tang and Zhi-Qin Yuan

J. Anal. Test., 2022, 6, 204
DOI: 10.1007/s41664-022-00220-4

Pyridine salts and aliphatic chains regulating membrane-targeted ratiometric fluorescence probe for detection of SO2 in living cells

Yanling Liu, Tao Zhang, Fangjun Huo and Caixia Yin

Dyes and Pigments, 2022, 205, 110540
DOI: 10.1016/j.dyepig.2022.110540

NIR-II-excited off-on-off fluorescent nanoprobes for sensitive molecular imaging in vivo

Yufu Tang, Yuanyuan Li, Chunxu He, Zhen Wang, Wei Huang, Quli Fan and Bin Liu

Nat Commun, 2025, 16
DOI: 10.1038/s41467-024-55096-y

Alkyl chain regulated cytomembrane and mitochondria targeting fluorescent probes for ratiometric sensing SO2 and its bio-application in mice model

Tao Zhang, Lijuan Li, Fangjun Huo, Weijie Zhang, Jianbin Chao and Caixia Yin

Sensors and Actuators B: Chemical, 2021, 342, 130041
DOI: 10.1016/j.snb.2021.130041

Ratiometric and reversible detection of endogenous SO2 and HCHO in living cells and mice by a near-infrared and dual-emission fluorescent probe

Mengzhao Wang, Qinglong Liu, Xin Sun, Shuo Zheng, Yanyan Ma, Yun Wang, Mei Yan, Zhengliang Lu, Chunhua Fan and Weiying Lin

Sensors and Actuators B: Chemical, 2021, 335, 129649
DOI: 10.1016/j.snb.2021.129649

A quinoline-coumarin near-infrared ratiometric fluorescent probe for detection of sulfur dioxide derivatives

Feng-Ting Liu, Na Li, Yong-Shun Chen, Hui-Ying Yu, Jun-Ying Miao and Bao-Xiang Zhao

Analytica Chimica Acta, 2022, 1211, 339908
DOI: 10.1016/j.aca.2022.339908

Dual-Targeting into the Mitochondria of Cancer Cells for Ratiometric Investigation of the Dynamic Fluctuation of Sulfur Dioxide and Formaldehyde with Two-Photon Integrated Semiconducting Polymer Dots

Qiang Zhang, Ziwei Zhang, Xiaoxiao Hu, Junyong Sun and Feng Gao

ACS Appl. Mater. Interfaces, 2022, 14, 179
DOI: 10.1021/acsami.1c18049

Dual-response and lysosome-targeted fluorescent probe for viscosity and sulfur dioxide derivatives

Feng Li, Bang-Zhao Zhou, Wen Yao, Shou-Kang Sun, Jun-Ying Miao, Bao-Xiang Zhao and Zhao-Min Lin

Analytica Chimica Acta, 2023, 1239, 340721
DOI: 10.1016/j.aca.2022.340721

Lysozyme-targeted ratiometric fluorescent probe for SO2 in living cells

Yang Lu, Haidong Li, Qichao Yao, Wen Sun, Jiangli Fan, Jianjun Du, Jingyun Wang and Xiaojun Peng

Dyes and Pigments, 2020, 180, 108440
DOI: 10.1016/j.dyepig.2020.108440

Highly sensitive and selective water-soluble fluorescent probe for the detection of formaldehyde in leather products

Yansong Wang, Xiaolong Sun, Qingxin Han, Tony D. James and Xuechuan Wang

Dyes and Pigments, 2021, 188, 109175
DOI: 10.1016/j.dyepig.2021.109175

Reversible Reaction‐Based Fluorescent Probes for Dynamic Sensing and Bioimaging

Hui Liu, Sisi Wang, Hu Gao and Zhen Shen

Eur J Org Chem, 2020, 2020, 5647
DOI: 10.1002/ejoc.202000359

A mitochondria-targeted fluorescent probe for reversible recognition of sulfur dioxide/formaldehyde and its application in cell imaging

Lin Liu, Di Zhang, Man Li, Jiacheng Shi, Fengqi Guo, Jie Guo and Tieliang Wang

Journal of Molecular Structure, 2023, 1274, 134459
DOI: 10.1016/j.molstruc.2022.134459

A reversible NIR fluorescent probe for monitoring of SO2 and formaldehyde in live cells and zebrafish

Hanchuang Zhu, Xue Zhang, Caiyun Liu, Yan Zhang, Meijun Su, Xiaodi Rong, Xin Wang, Mengyuan Liu, Xiaohui Zhang, Wenlong Sheng and Baocun Zhu

Sensors and Actuators B: Chemical, 2022, 366, 131962
DOI: 10.1016/j.snb.2022.131962

Developing a dual-site fluorescent probe for simultaneously discriminating Cys/Hcy and GSH, and visualizing metabolism of Cys to SO2

Jianbin Chao, Jiamin Zhao, Yongbin Zhang, Fangjun Huo and Caixia Yin

Sensors and Actuators B: Chemical, 2021, 346, 130569
DOI: 10.1016/j.snb.2021.130569

Au@Ag@ZIF-8 multifunction probe with internally o-phenylenediamine encoding for the colorimetric, fluorescence, and SERS multi-mode optical detection of reactive sulfur species

Xia Zhou, Xiaoling Lin, Haiqiu Huang, Ping Li, Jiamin Wu, Xueqin Huang, Huaihong Cai, Hai Han, Junxia Zheng and Haibo Zhou

Sensors and Actuators B: Chemical, 2022, 361, 131762
DOI: 10.1016/j.snb.2022.131762

Recent progress in the development of organic small-molecule and functional material fluorescent probes for formaldehyde detection and imaging

Zi-Xuan Chu, Qi Song, Yong-Qiang Zhang and Jie Jiang

Coordination Chemistry Reviews, 2023, 495, 215338
DOI: 10.1016/j.ccr.2023.215338

Multifunctional fluorescent probes "killing two birds with one stone" - recent progress and outlook

Ya-Lin Qi, Li-Li Chen, Long Guo, Yu-Yao Cao, Hai-Rong Wang, Yu-Shun Yang, Ya-Dong Lu and Hai-Liang Zhu

Applied Materials Today, 2020, 21, 100877
DOI: 10.1016/j.apmt.2020.100877

Sequentially Activated Probe Design Strategy for Analyzing Metabolite Crosstalk in a Biochemical Cascade

Juan Cheng, Yong Ren, Yujie Huang, Xiaozhuan Li, Mingzhu Huang, Feng Han, Xingguang Liang and Xin Li

Anal. Chem., 2020, 92, 1409
DOI: 10.1021/acs.analchem.9b04576

Bicyclic-Ammonium-Incorporated Ylidic Nitrogen Groups for Strong π-Electron Donation in Push–Pull Benzene π-Conjugated Systems

Hikaru Fujita, Takanari Arai, Naoto Kuchiki and Munetaka Kunishima

Org. Lett., 2024, 26, 7313
DOI: 10.1021/acs.orglett.4c02378

Gold nanoprism/Tollens’ reagent complex as plasmonic sensor in headspace single-drop microextraction for colorimetric detection of formaldehyde in food samples using smartphone readout

Tong Qi, Mengyuan Xu, Yao Yao, Wenhui Chen, Mengchan Xu, Sheng Tang, Wei Shen, Dezhao Kong, Xingwei Cai, Haiwei Shi and Hian Kee Lee

Talanta, 2020, 220, 121388
DOI: 10.1016/j.talanta.2020.121388

Employing an ICT-FRET Integration Platform for the Real-Time Tracking of SO2 Metabolism in Cancer Cells and Tumor Models

Weijie Zhang, Fangjun Huo, Fangqin Cheng and Caixia Yin

J. Am. Chem. Soc., 2020, 142, 6324
DOI: 10.1021/jacs.0c00992

A long-wavelength fluorescent probe with a large Stokes shift for lysosome-targeted imaging of Cys and GSH

Yi-Hang Sun, Hai-Hao Han, Jia-Min Huang, Jia Li, Yi Zang and Cheng-Yun Wang

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 261, 120055
DOI: 10.1016/j.saa.2021.120055

Preparation of robust fluorescent probes for tracking endogenous formaldehyde in living cells and mouse tissue slices

Yonghe Tang, Yuping Zhao and Weiying Lin

Nat Protoc, 2020, 15, 3499
DOI: 10.1038/s41596-020-0384-7

Rational design and application of sulfur dioxide/formaldehyde reversible near-infrared fluorescence probe

Zujun Xu, Xue Zhang, Hanchuang Zhu, Mingchang Gao, Shaofang Sun, Caiyun Liu and Liping Qiu

Journal of Luminescence, 2022, 251, 119148
DOI: 10.1016/j.jlumin.2022.119148

Heat Stroke in Cell Tissues Related to Sulfur Dioxide Level Is Precisely Monitored by Light-Controlled Fluorescent Probes

Weijie Zhang, Fangjun Huo, Yongkang Yue, Yongbin Zhang, Jianbin Chao, Fangqin Cheng and Caixia Yin

J. Am. Chem. Soc., 2020, 142, 3262
DOI: 10.1021/jacs.9b13936

Design of a New Hydrazine Moiety-Based Near-Infrared Fluorescence Probe for Detection and Imaging of Endogenous Formaldehyde In Vivo

Ning Ding, Zhao Li, Yitong Hao and Chengxiao Zhang

Anal. Chem., 2022, 94, 12120
DOI: 10.1021/acs.analchem.2c02166

Structure-regulated mitochondrial-targeted fluorescent probe for sensing and imaging SO2 in vivo

Qinqin Tian, Xianlin Lu and Wei He

Bioorganic Chemistry, 2023, 138, 106656
DOI: 10.1016/j.bioorg.2023.106656

A New Strategy: Distinguishable Multi-substance Detection, Multiple Pathway Tracing Based on a New Site Constructed by the Reaction Process and Its Tumor Targeting

Yongfei Huang, Yongbin Zhang, Fangjun Huo, Jianbin Chao, Fangqin Cheng and Caixia Yin

J. Am. Chem. Soc., 2020, 142, 18706
DOI: 10.1021/jacs.0c10210

Progress in the Study of Optical Probes for the Detection of Formaldehyde

Xuexuan Xu, Erpei Yang and Yanyan Chen

Critical Reviews in Analytical Chemistry, 2022, 1
DOI: 10.1080/10408347.2022.2107870

Reversible polysiloxane-based near-infrared fluorescent probe for monitoring the redox cycles between HClO/SO2 in mitochondria and in vivo

Yujing Zuo, Xiaoni Wang, Zhiming Gou and Weiying Lin

Sensors and Actuators B: Chemical, 2021, 344, 130217
DOI: 10.1016/j.snb.2021.130217

Advances in small organic molecule fluorescent probes for formaldehyde detection and imaging in pathophysiological processes: A comprehensive review

Tong-Tong Jia, Guohui Kang, Lirong Jiang, Zhaozhou Li, Rui Zhao, Jian-Hua Qin, Huawei Niu and Lu-Fang Ma

TrAC Trends in Analytical Chemistry, 2025, 191, 118338
DOI: 10.1016/j.trac.2025.118338

Rational Design of A NIR Ratiometric Fluorescent Probe with Large Stokes Shift for Sulfite Detection

Yali Cui, Chenggong Xu, Tian Wu and Yanmei Zhou

J. Electrochem. Soc., 2021, 168, 057502
DOI: 10.1149/1945-7111/abfa5a

An overview on recent advances of reversible fluorescent probes and their biological applications

Yanan Huang, Xuebin Cao, Yawen Deng, Xingyu Ji, Weina Sun, Shiyu Xia, Shuo Wan, Hongxia Zhang, Ronglian Xing, Jun Ding and Chunguang Ren

Talanta, 2024, 268, 125275
DOI: 10.1016/j.talanta.2023.125275

Dual-Fluorophore and Dual-Site Multifunctional Fluorescence Sensor for Visualizing the Metabolic Process of GHS to SO2 and the SO2 Toxicological Mechanism by Two-Photon Imaging

Chunlin Jing, Yingzhe Wang, Xuerui Song, Xinxin Li, Manchang Kou, Guolin Zhang, Wei Dou and Weisheng Liu

Anal. Chem., 2022
DOI: 10.1021/acs.analchem.2c04333

Design strategies and recent advances in reversible fluorescent probes for redox

Yifei Neng, Siyue Ma, Siyu Long, Suyue Guo, Na Zhang and Guang Chen

Dyes and Pigments, 2024, 224, 112055
DOI: 10.1016/j.dyepig.2024.112055

Covalent Interactions of Anthocyanins with Proteins: Activity-Based Protein Profiling of Cyanidin-3-O-glucoside

Jun Hu, Tingxin Yu, Kuanchen Huang, Chujie Liang, Yue Li, Xusheng Li, Jianxia Sun and Weibin Bai

J. Agric. Food Chem., 2024, 72, 16790
DOI: 10.1021/acs.jafc.4c03869

Lysosomal-targeted fluorescent probe for detecting SO2 derivatives in human umbilical vein endothelial cells

Feng Li, Xian-Fang Liu, Bao-Xiang Zhao and Zhao-Min Lin

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 331, 125753
DOI: 10.1016/j.saa.2025.125753

Endogenous formaldehyde responsive fluorescent probe for bioimaging

Ning-Bo Yi, Xing-Jie Hu, Fei Wang, Si-Yi Chen, Xiao-Xue Xu, Xin Li, Hao Wang, Taolei Sun, Zeng-Ying Qiao and Dong-Bing Cheng

Nano Res., 2023, 16, 13029
DOI: 10.1007/s12274-023-5766-z

Research Progress of Sulfur Dioxide Fluorescent Probe Targeting Mitochondria

Yifang Li, Yao Wang, Huawei Niu, Xiujin Chen, Zhaozhou Li and Yongguo Wang

Chinese Journal of Organic Chemistry, 2023, 43, 1952
DOI: 10.6023/cjoc202210030

Formaldehyde in biological systems: Involving sources, related diseases and reaction-based fluorescent detection

Chunfei Wang and Xuanjun Zhang

TrAC Trends in Analytical Chemistry, 2023, 168, 117298
DOI: 10.1016/j.trac.2023.117298

A novel naphthalimide-based fluorescent probe for the colorimetric and ratiometric detection of SO2 derivatives in biological imaging

Linlin Yang, Nan Yang, Pengli Gu, Yihua Zhang, Xianyu Gong, Shichao Zhang, Junwan Li, Liguo Ji and Guangjie He

Bioorganic Chemistry, 2022, 123, 105801
DOI: 10.1016/j.bioorg.2022.105801

Mitochondria-targeted reversible ratiometric fluorescent probe for monitoring SO2/HCHO in living cells

Tao Zhang, Caixia Yin, Yongbin Zhang, Jianbin Chao, Guangming Wen and Fangjun Huo

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 234, 118253
DOI: 10.1016/j.saa.2020.118253