Halogen-bonding catalysis enables the organocatalytic Fridel–Crafts arylation of aldehydes with indoles.
I⋯π halogen bond catalysis on the [4+2] cycloaddition reaction was investigated. There are two modes either on the ethenyl or the five-membered ring of 2-alkenylindole. Moreover, the stereoselectivity of the endo and exo pathways was compared.
This review summarises methods to synthesise and apply fluorine- and polyfluoroalkyl/aryl-substituted 1,2,3-triazoles. Focus is devoted to recent examples and those where the properties of both the 1,2,3-triazole and fluorine groups are important.
Dicationic selenonium salts with imidazopyridine substituents serve as efficient chalcogen bond activators in Povarov cyclizations and gold catalysis.
This tutorial review will focus on the recently evolved chalcogen bonding catalysis. Emphasis will be given to the basics of non-covalent bonding, chiral chalcogen bonding catalysis, chiral separation, and chalcogen bonding in biomolecules.