A series of 1H-1,2,3-triazoles 12a–g and 13a–g having 4H-pyrano[2,3-d]pyrimidine and D-glucose rings was synthesized by click chemistry and their inhibitory activity against UDP-N-acetylglucosamine enolpyruvyl transferases (MurA & MurZ) was examined.
The past decade has witnessed significant progress in synthesizing structurally diverse and biologically relevant pyrano[2,3-c]pyrazole derivatives through the integration of green methodologies.
Here, we report a simple, efficient, and green protocol for the one-pot synthesis of pyrano[2,3-c]pyrazole derivatives via a sequential three-component strategy using aromatic aldehydes, malononitrile and pyrazolinone in a water–SDS–IL system.
Anchoring of Ni(II) complex onto the surface of mesoporous KIT-6 modified under mild reaction conditions as a highly efficient and reusable nanocatalyst for the synthesis of 5-substituted tetrazoles and pyranopyrazoles.
Starch as catalyst for organic reactions.