Photocatalytic oxidative hydroacylation with alcohols†
Abstract
Herein, we report a photocatalytic method for oxidative hydroacylation with alcohols. Under photoirradiation and a catalytic amount of TBADT, different electrophiles (azodicarboxylates, N-phenylmaleimide, benzylidenemalononitrile and phenyl vinyl sulfone) underwent hydroacylation with alcohols in good yields. The method was also applied to achieve a convenient synthesis of the anti-depressant drug moclobemide.