Recent advances of polyoxometalates in multi-functional imaging and photothermal therapy
The recent advances of polyoxometalate clusters in terms of near infrared photothermal properties for targeted tumor therapy have been summarized while the combined applications with various bio-imaging techniques and chemotherapies are reviewed.
Three-dimensional scaffold-free microtissues engineered for cardiac repair
In this review article, we present the state-of-the-art approaches and recent advancements in the engineering of scaffold-free cardiac microtissues for myocardial repair.
Communication
Near-room-temperature reversible giant barocaloric effects in [(CH3)4N]Mn[N3]3 hybrid perovskite
We report giant reversible barocaloric effects in [(CH3)4N]Mn[N3]3 hybrid organic–inorganic perovskite, near its first-order cubic-monoclinic structural phase transition at T0 ∼ 305 K.
An artificial protein-probe hybrid as a responsive probe for ratiometric detection and imaging of hydrogen peroxide in cells
A novel fluorescent protein-probe hybrid was devised for ratiometric detection and imaging of intracellular H2O2 with high sensitivity and selectivity.
Hybrid magneto-luminescent iron oxide nanocubes functionalized with europium complexes: synthesis, hemolytic properties and protein corona formation
In this work, we carried out the preparation of a multifunctional hybrid nanostructures towards biomedical applications with a solid background for further applications of these materials containing new surface functionalities of nanobiotechnology.
Metal–DNA coordination based bioinspired hybrid nanospheres for in situ amplification and sensing of microRNA
Based on coordination-driven self-assembly techniques, a facile approach for the intracellular delivery of nucleic acid into living cells and in situ intracellular targeted miRNA bioimaging using synthesized nano-wire balls (NWs) is proposed.
Brimonidine–montmorillonite hybrid formulation for topical drug delivery to the eye
Ternary hybrids of brimonidine, montmorillonite and polyvinyl alcohol (BMD-MMT@PVA) can improve ocular drug bioavailability when administered topically to the eye.
Leucine-activated nanohybrid biofilm for skin regeneration via improving cell affinity and neovascularization capacity
Nanohybrids containing amino acid are doped into biodegradable nanofibrous membranes, which improves the cell affinity, the migration and growth of fibroblasts, and the neovascularization capacity, comprehensively accelerating a rapid wound healing.
Fabrication of noble metal nanoparticles decorated on one dimensional hierarchical polypyrrole@MoS2 microtubes
Herein, we present a facile strategy to fabricate noble metal (Ag, Au, Pd) decorated on PPy@MoS2 microtubes. As a proof of application, the ternary PPy@MoS2@Au hybrids reveal excellent enzyme-like catalytic performance.
A cell membrane vehicle co-delivering sorafenib and doxorubicin remodel the tumor microenvironment and enhance immunotherapy by inducing immunogenic cell death in lung cancer cells
Cancer immunotherapy is a promising approach for cancer therapy but is usually hindered by the inhibition of the tumor microenvironment (TME).
Paper
Luminescent hybrid coatings prepared by a sol–gel process for a textile-based pH sensor
Luminescent hybrid materials which contain fluorene and stilbene based fluorophores were coated onto cotton fabrics to design textile-based pH sensors.
Biomimetic immunomagnetic gold hybrid nanoparticles coupled with inductively coupled plasma mass spectrometry for the detection of circulating tumor cells
Immunomagnetic beads are important tools for the isolation and detection of circulating tumor cells (CTCs).
Sequential delivery of synergistic drugs by silica nanocarriers for enhanced tumour treatment
Environmentally-responsive nanocarriers exhibiting a synergistic effect, where pH-triggered release of the cytotoxic cap followed by diffusion-controlled release of the drug cargo led to essentially complete cell death.
Paper
Nanoporous hybrid core–shell nanoparticles for sequential release
Silica inside – organosilica outside, and nanoporous throughout: Drug molecules to be released sequentially from novel core–shell nanoparticles select their location (core/shell) autonomously.
A novel multifunctional carbon aerogel-coated platform for osteosarcoma therapy and enhanced bone regeneration
The implantation of multifunctional carbon aerogel (CA)-coated β-TCP scaffolds for synchronously improving the photothermal ablation and enhanced bone regeneration of osteosarcoma.
The effect of hybrid coatings based on hydrogel, biopolymer and inorganic components on the corrosion behavior of titanium bone implants
Dependence of variation of Ti bone implant corrosion behavior on the composition of bioactive coating.
A ZnO–curcumin nanocomposite embedded hybrid collagen scaffold for effective scarless skin regeneration in acute burn injury
A nano-engineered hybrid collagen scaffold enables healing of severe burn injuries without the formation of scars by stimulating key bio-factors.
Paper
A biomimetic hybrid material consisting of CaCO3 mesoporous microspheres and an alternating copolymer for reversed-phase HPLC
Inspired by egg shells, amphiphilic copolymer-modified monodisperse mesoporous CaCO3 microspheres were applied as a separation material.
Lysosome-specific sensing and imaging of pH variations in vitro and in vivo utilizing a near-infrared boron complex
A NIR lysosome-targeting boron complex has been developed based on hemicyanine for monitoring pH variations in vitro and in vivo.
Paper
A muscle mimetic polyelectrolyte–nanoclay organic–inorganic hybrid hydrogel: its self-healing, shape-memory and actuation properties
In this investigation, we report a non-covalent (ionic interlocking and hydrogen bonding) strategy of self-healing in a covalently crosslinked organic–inorganic hybrid nanocomposite hydrogel, with specific emphasis on tuning its properties fitting into a muscle mimetic material.
A highly sensitive label-free electrochemical immunosensor based on an aligned GaN nanowires array/polydopamine heterointerface modified with Au nanoparticles
Taking advantage of a nanowire array configuration and a semiconductor/polymer heterointerface, a highly sensitive label-free electrochemical immunosensor was developed through integration of polydopamine on an aligned GaN nanowire surface.
Hybrid particles derived from alendronate and bioactive glass for treatment of osteoporotic bone defects
Novel hybrid particles are synthesized using alendronate and bioactive glass, which can stimulate regeneration of osteoporotic bone defects.
A hybrid 3D-printed aspirin-laden liposome composite scaffold for bone tissue engineering
Schematic illustration of hybrid 3D-printed aspirin-laden liposome composite scaffold.
About this collection
Editorial Board member for Journal of Material Chemistry B Claus Feldmann (Karlsruhe Institute of Technology, Germany), introduces this Editor’s Choice collection on hybrid materials:
In order to bring different material properties together, different chemical compounds are nowadays combined with great virtuosity and result in a fascinating design of hybrid materials with properties and functions that go far beyond those of the individual components. Special attention is being paid to combinations of carbon materials, polymers and biopolymers, natural substances or inorganic metal oxides. The forms of matter are also broadly diversified, ranging from nanoparticles to nanolayers via porous materials to nanostructured bulk materials. The desired properties and functions are as diverse as the materials themselves. In particular, carriers for drug delivery, imaging, sensing/biosensing and bioregeneration of almost all types of tissue are intensely discussed.
In the current collection, I have selected outstanding papers published during recent years in Journal of Materials Chemistry B and Materials Advances that address the extremely wide area of hybrid materials. These articles provide fascinating insights and perspectives with regard to multi-functional imaging, drug delivery, sensing, tissue engineering and tissue regeneration, and nanostructured semiconductors.