Front cover
Introduction to the themed collection on nanoceria research
Guest editor Robert Yokel introduces the Nanoceria Research themed collection of Environmental Science: Nano.
Exploring the properties and applications of nanoceria: is there still plenty of room at the bottom?
Nanoceria is an exceptionally versatile, commercially valuable catalytic material whose properties vary dramatically from that of the bulk material.
Catalytic properties and biomedical applications of cerium oxide nanoparticles
Nanoceria – CeO2−x redox active nanoparticles targeting ROS and RNS.
Environmental release, fate and ecotoxicological effects of manufactured ceria nanomaterials
This critical review presents the sources and sinks of nanoceria in the environment, detection and characterization methods, fate and transport processes, toxicity and likelihood of toxicity in soil and water.
Behavior of nanoceria in biologically-relevant environments
Cerium oxide nanoparticles (nanoceria) have gained considerable attention in biological research due to their anti-oxidant like behaviour and regenerative nature.
The yin: an adverse health perspective of nanoceria: uptake, distribution, accumulation, and mechanisms of its toxicity
This critical review identifies nanoceria's pharmacokinetics and adverse effects, discloses uncertainties and unknowns, and makes recommendations to address research gaps.
Nanoceria: factors affecting its pro- and anti-oxidant properties
Nanoceria redox properties are affected by environmental factors, such as local pH, additives that coat the surface, and reactive ligands.
Applications and implications of nanoceria reactivity: measurement tools and environmental impact
A critical survey of recent research activities exploring the reactivity of nanoceria particles, their benefits and potential risks for the environment.
Bioavailability, distribution and clearance of tracheally instilled, gavaged or injected cerium dioxide nanoparticles and ionic cerium
Nanoparticulate and ionic cerium is cleared slowly from the lungs. Bioavailability from the gut is far lower than from the lungs.
Nanoceria biodistribution and retention in the rat after its intravenous administration are not greatly influenced by dosing schedule, dose, or particle shape
Nanoceria distribution and retention in the rat is not greatly affected by its dose, size, shape, or dosing schedule.
Metabolomic effects in HepG2 cells exposed to four TiO2 and two CeO2 nanomaterials
In a metabolomics study in HepG2 cells, nanomaterials decreased GSH precursors (glutamate and cysteine), GSH itself and many GSH metabolites.
Effect of cerium oxide nanoparticles on asparagus lettuce cultured in an agar medium
CeO2 nanoparticles showed a higher toxicity to asparagus lettuce in an agar medium than in aqueous suspensions.
About this collection
This focused issue contains perspectives from a workshop on nanoceria and original research reports of studies focusing on nanocerias. The workshop was organized and attended by researchers actively investigating the beneficial and untoward effects of nanocerias. The workshop focus was to try to understand the bases of these divergent effects. Perspectives of workshop panels that addressed what we know, identified data gaps, and recommended what needs to be determined about the chemical, biological, human health, and environmental aspects of nanoceria constitute the first part of this issue. Previously unpublished results of research studies of nanocerias, submitted in response to an open call, comprise the second part of this issue. This issue is the most comprehensive and current source of information on the chemistry, biology, and beneficial and untoward effects of nanocerias.