Themed collection Analyst Review Articles 2022
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Preparation and application of chitosan-based fluorescent probes
Biomass materials have abundant natural resources, renewability and good biochemical compatibility, so biomass-based fluorescent materials prepared from biomass materials have gradually become a research hotspot.
Analyst, 2022,147, 4657-4673
https://doi.org/10.1039/D2AN01070D
Recent advances in biological detection with rolling circle amplification: design strategy, biosensing mechanism, and practical applications
Rolling circle amplification (RCA) is a simple and isothermal DNA amplification technique that is used to generate thousands of repeating DNA sequences using circular templates under the catalysis of DNA polymerase.
Analyst, 2022,147, 3396-3414
https://doi.org/10.1039/D2AN00556E
Recent progress in electrochemiluminescence microscopy analysis of single cells
An overview of recent progress in electrochemiluminescence microscopy analysis of single cells classified according to different ECL routes, namely the oxidative-reduction, low oxidation potential, catalytic and direct oxidation routes.
Analyst, 2022,147, 2884-2894
https://doi.org/10.1039/D2AN00709F
Recent advances in spheroid-based microfluidic models to mimic the tumour microenvironment
Microfluidic platforms with 3D tumour spheroid culture provide platforms to study the multi-cellular interactions and external stimuli in the complex tumour microenvironment.
Analyst, 2022,147, 2023-2034
https://doi.org/10.1039/D2AN00172A
Semiconductor-based surface enhanced Raman scattering (SERS): from active materials to performance improvement
We review the recent progress in semiconductor-based SERS. We mainly discuss the enhancement mechanism, SERS-active materials for semiconductors, and potential strategies to improve the SERS performance.
Analyst, 2022,147, 1257-1272
https://doi.org/10.1039/D1AN02165F
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Practical considerations for quantitative and reproducible measurements with stimulated Raman scattering microscopy
This tutorial review presents the most important practical considerations for sample preparation, instrument set-up, image acquisition and data analysis to obtain reproducible SRS measurements.
Analyst, 2022,147, 4642-4656
https://doi.org/10.1039/D2AN00817C
PharmaChk: a decade of research and development towards the first quantitative, field-based medicine quality screening instrument
We describe the scientific, engineering work over the first ten years of PharmaChk, the first quantitative, portable instrument for medicine quality screening, to illustrate what it takes for academic labs to translate observations into interventions.
Analyst, 2022,147, 3805-3816
https://doi.org/10.1039/D2AN00284A
Applications of upconversion nanoparticles in analytical and biomedical sciences: a review
Upconversion nanoparticles have gained more attention due to their unique photon conversion capability from an incident wavelength to a more suitable emission wavelength at a designated site, thus improving their scope in analytical and biomedical sciences.
Analyst, 2022,147, 3155-3179
https://doi.org/10.1039/D1AN02170B
Electrochemiluminescent sensor based on an aggregation-induced emission probe for bioanalytical detection
In recent years, with the rapid development of electrochemiluminescence (ECL) sensors, more luminophores have been designed to achieve high-throughput and reliable analysis.
Analyst, 2022,147, 2338-2354
https://doi.org/10.1039/D2AN00349J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Recent advances and applications to cultural heritage using ATR-FTIR spectroscopy and ATR-FTIR spectroscopic imaging
A tutorial on non-destructive and high spatial resolution ATR-FTIR spectroscopic imaging approaches for the analysis of cultural heritage objects.
Analyst, 2022,147, 1777-1797
https://doi.org/10.1039/D2AN00005A
Recent advances in small molecular near-infrared fluorescence probes for a targeted diagnosis of the Alzheimer disease
Near-infrared small molecular fluorescence probes for targeted diagnosis of Alzheimer's disease.
Analyst, 2022,147, 4701-4723
https://doi.org/10.1039/D2AN01327D
Comprehensive two-dimensional gas chromatography with mass spectrometry: an advanced bioanalytical technique for clinical metabolomics studies
This review highlights the current state of knowledge in the development of GC × GC-MS for the analysis of clinical metabolites. Selected applications are described as well as our perspectives on current challenges and potential future directions.
Analyst, 2022,147, 3974-3992
https://doi.org/10.1039/D2AN00584K
Use of MALDI-TOF mass spectrometry for virus identification: a review
The possibilities of virus identification, including SARS-CoV-2, by MALDI-TOF mass spectrometry are discussed in this review.
Analyst, 2022,147, 3131-3154
https://doi.org/10.1039/D2AN00431C
Metabolomics-based mass spectrometry methods to analyze the chemical content of 3D organoid models
Mass spectrometry-based metabolomics approaches to characterize the complex intracellular chemistry of organoids are reviewed, expanding the field of organoid research.
Analyst, 2022,147, 2918-2929
https://doi.org/10.1039/D2AN00599A
Biorecognition antifouling coatings in complex biological fluids: a review of functionalization aspects
Recent progress in biointerface research has highlighted the role of antifouling functionalizable coatings in the development of advanced biosensors for point-of-care applications dealing with real-world complex samples.
Analyst, 2022,147, 2597-2614
https://doi.org/10.1039/D2AN00436D
Cancer drug resistance related microRNAs: recent advances in detection methods
MiRNAs are related to cancer drug resistance through various mechanisms. The advanced detection methods for the miRNAs are reviewed.
Analyst, 2022,147, 2615-2632
https://doi.org/10.1039/D2AN00171C
Tandem-trapped ion mobility spectrometry/mass spectrometry (tTIMS/MS): a promising analytical method for investigating heterogenous samples
This review focuses on the instrumental development and potential applications of Tandem-Trapped Ion Mobility Spectrometry/Mass Spectrometry (tTIMS/MS) for protein structure elucidation.
Analyst, 2022,147, 2317-2337
https://doi.org/10.1039/D2AN00335J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.147/content/NewImages/open-access-icon-orange.png)
Single-cell droplet microfluidics for biomedical applications
This review focuses on the recent advances in the fundamentals of single-cell droplet microfluidics and its applications in biomedicine, providing insights into design and establishment of single-cell microsystems and their further performance.
Analyst, 2022,147, 2294-2316
https://doi.org/10.1039/D1AN02321G
Detecting bacterial infections in wounds: a review of biosensors and wearable sensors in comparison with conventional laboratory methods
Review on laboratory-based methods and biosensors and wearable sensors for detecting wound infection by aerobic and anaerobic bacteria.
Analyst, 2022,147, 1756-1776
https://doi.org/10.1039/D2AN00157H
“Writing biochips”: high-resolution droplet-to-droplet manufacturing of analytical platforms
Depletion-free molecular ink deposition with accurate volume control allows for the fabrication of droplet-based bioanalytical assays.
Analyst, 2022,147, 1294-1312
https://doi.org/10.1039/D1AN02295D
Recent progress in small-molecule fluorescent probes for endoplasmic reticulum imaging in biological systems
Small-molecule fluorescent probes for endoplasmic reticulum imaging in biological systems are summarized.
Analyst, 2022,147, 987-1005
https://doi.org/10.1039/D1AN02290C
About this collection
This themed collection features recent review articles published in Analyst.