Synergistic Integration of MXene Nanostructures into Electrospun Fibers for Advanced Biomedical Engineering Applications

Abstract

MXene-based architectures have paved the way in various fields, particularly in the healthcare area, owning to remarkable physiochemical and electromagnetic characteristics. The modification of MXene structures, along with their combination with polymeric networks, have also gained considerable prominence to further progress their features. The combination of electrospun fibers with MXene faces would be promising in this era since electrospinning has been declared a mature technique that is now being spun out into commercial biomedical applications. The introduction of MXene into the electrospun fibrous frameworks has highlighted outcomes in various biomedical usages, including cancer therapy, controlled drug delivery, antimicrobial targets, sensors, and tissue engineering. Correspondingly, this review describes the employed strategies for the preparation of electrospun configurations in tandem with the MXene nanostructures with fabulous characteristics. Then, the advantages of MXene-decorated electrospun fibers for use in biomedical applications are comprehensively enlightened. According to the investigations, rich surface functional groups, hydrophilicity, large surface area, photothermal features, and antimicrobial and antibacterial activities of the MXene could synergize the performance of electrospun layers to engineer versatile biomedical targets. Also, the future of this path is clarified to combat the challenges related to the electrospun fibers decorated with MXene nanosheets.