Issue 20, 2021

Chromo-fluorogenic sensing using vitamin B6 cofactors and their derivatives: a review

Abstract

Chromo-fluorogenic chemosensors designed by using a signaling unit (chromophore/fluorophore) and a recognition unit are extensively developed for the sensing of various bioactive and toxic analytes owing to their low-cost, simplicity, and high selectivity and sensitivity. Recently, vitamin B6 cofactors like pyridoxal and pyridoxal 5′-phosphate (PLP) have been employed as a recognition unit for the design of chromo-fluorogenic chemosensors using various organic dyads and functionalized nanomaterials. This review summarizes the chromo-fluorogenic chemosensors developed using the cofactors pyridoxal and PLP. The design of sensors, sensing mechanisms and practical applications of the developed sensors are also discussed. The main aim of this review is to provide future scope for developing chemosensors using the bioactive cofactors as the recognition unit by presenting the results from our research group and the contributions from other groups.

Graphical abstract: Chromo-fluorogenic sensing using vitamin B6 cofactors and their derivatives: a review

Article information

Article type
Perspective
Submitted
01 мар 2021
Accepted
15 апр 2021
First published
15 апр 2021

New J. Chem., 2021,45, 8874-8897

Chromo-fluorogenic sensing using vitamin B6 cofactors and their derivatives: a review

S. K. Sahoo, New J. Chem., 2021, 45, 8874 DOI: 10.1039/D1NJ01008E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements