Issue 21, 2019

Manganese-catalyzed direct C–C coupling of α-C–H bonds of amides and esters with alcohols via hydrogen autotransfer

Abstract

Herein we report an efficient manganese-catalyzed C-alkylation of unactivated amides and tert-butyl acetate using alcohols as alkylating agents. This elegant approach exhibits a broad substrate scope providing the C–C coupled products of amides via a hydrogen auto-transfer strategy using aryl, heteroaryl, and aliphatic alcohols.

Graphical abstract: Manganese-catalyzed direct C–C coupling of α-C–H bonds of amides and esters with alcohols via hydrogen autotransfer

Supplementary files

Article information

Article type
Communication
Submitted
20 дек 2018
Accepted
12 мар 2019
First published
20 мар 2019

Dalton Trans., 2019,48, 7094-7099

Manganese-catalyzed direct C–C coupling of α-C–H bonds of amides and esters with alcohols via hydrogen autotransfer

J. Rana, V. Gupta and E. Balaraman, Dalton Trans., 2019, 48, 7094 DOI: 10.1039/C8DT05020A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements