Issue 7, 2017

Towards next-generation label-free biosensors: recent advances in whispering gallery mode sensors

Abstract

Whispering gallery mode biosensors have been widely exploited over the past decade to study molecular interactions by virtue of their high sensitivity and applicability in real-time kinetic analysis without the requirement to label. There have been immense research efforts made for advancing the instrumentation as well as the design of detection assays, with the common goal of progressing towards real-world sensing applications. We therefore review a set of recent developments made in this field and discuss the requirements that whispering gallery mode label-free sensors need to fulfill for making a real world impact outside of the laboratory. These requirements are directly related to the challenges that these sensors face, and the methods proposed to overcome them are discussed. Moving forward, we provide the future prospects and the potential impact of this technology.

Graphical abstract: Towards next-generation label-free biosensors: recent advances in whispering gallery mode sensors

Article information

Article type
Critical Review
Submitted
30 дек 2016
Accepted
22 фев 2017
First published
07 мар 2017

Lab Chip, 2017,17, 1190-1205

Towards next-generation label-free biosensors: recent advances in whispering gallery mode sensors

E. Kim, M. D. Baaske and F. Vollmer, Lab Chip, 2017, 17, 1190 DOI: 10.1039/C6LC01595F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements