Issue 42, 2017

Structure and reactivities of rhenium and technetium bis-arene sandwich complexes [M(η6-arene)2]+

Abstract

Sandwich complexes are important building blocks in medicinal inorganic chemistry for group 6 and 8 elements but are almost unknown for the manganese triad. We present the syntheses and full characterization of the mixed-arene 99Tc sandwich complexes [99Tc(η6-hmbz)(η6-C6H5–NH3)](PF6)2 and [99Tc(η6-hmbz)(η6-C6H5–Br)](PF6). Both comprise functionalities for conjugation to targeting molecules or for being included as substructures in pharmaceutically active lead compounds. Since η6-benzene ligands are too stably bound to be replaced with incoming ligands, we prepared naphthalene complexes [Re(η6-C6H6)(η6-napht)]+ and [Re(η6-napht)2]+. Their reactivities towards substitution are increased and one or both naphthalene ligands can be replaced with mono- or multi-dentate ligands. Combining the features of 99Tc and Re may lead to a molecule-based theranostic approach.

Graphical abstract: Structure and reactivities of rhenium and technetium bis-arene sandwich complexes [M(η6-arene)2]+

Supplementary files

Article information

Article type
Paper
Submitted
07 июн 2017
Accepted
18 июл 2017
First published
18 июл 2017

Dalton Trans., 2017,46, 14631-14637

Structure and reactivities of rhenium and technetium bis-arene sandwich complexes [M(η6-arene)2]+

G. Meola, H. Braband, S. Jordi, T. Fox, O. Blacque, B. Spingler and R. Alberto, Dalton Trans., 2017, 46, 14631 DOI: 10.1039/C7DT02072D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements