Sensing the impact of environment on small molecule differentiation of RNA sequences†
Abstract
Using pattern recognition of RNA with small molecules (PRRSM) with fluorescent RNA chemosensors and aminoglycosides, we reveal the impact of changing environmental conditions on the differentiation of a range of RNA structures as well as the ability to predict different sequence/size compositions of five canonical RNA motifs.
- This article is part of the themed collections: Celebrating the ChemComm Emerging Investigator Lectureship Winners and Chemosensors and Molecular Logic