The regioselective ring-opening of aryl oxiranes was investigated with various 4-hydroxycoumarins in dimethyl sulfoxide in the presence of 20 mol% FeCl3 as a catalyst at 110 °C.
Regioselective [3 + 3] benzannulation reactions of aurone derivatives and 1,3-bisnucleophiles afford substituted dibenzofurans. Arylsulfone-bearing nucleophiles react via elimination whereas glutaconate reacts via an air-oxidation pathway.
This review covers the advancement of aryl glyoxal as a prime synthetic equivalent in recent years for the synthesis of oxygen heterocycles.
Two copper-controlled reactions of 2H-azirines with TosMICs have been developed that provide two efficient and modular approaches to diverse substituted pyrimidines with non-electron-withdrawing substituents at position 4 or 6.
The category of bifunctional building blocks overrides many others because of their fascinating wide applicability in synthetic chemistry.