The regioselective ring-opening of aryl oxiranes was investigated with various 4-hydroxycoumarins in dimethyl sulfoxide in the presence of 20 mol% FeCl3 as a catalyst at 110 °C.
Regioselective [3 + 3] benzannulation reactions of aurone derivatives and 1,3-bisnucleophiles afford substituted dibenzofurans. Arylsulfone-bearing nucleophiles react via elimination whereas glutaconate reacts via an air-oxidation pathway.
This review covers the advancement of aryl glyoxal as a prime synthetic equivalent in recent years for the synthesis of oxygen heterocycles.
The category of bifunctional building blocks overrides many others because of their fascinating wide applicability in synthetic chemistry.
A new series of proximicin analogues containing a benzofuran moiety as the replacement of the di-furan scaffold of the parent compound were synthesised and evaluated for their anti-proliferative activities against human glioblastoma cells U-87 MG.