This review provides an overview of skipped dienes synthesis in the last five years. Metal-mediated, metal-free, synergistic/dual and metallaphotoredox catalysed reactions are analysed based on catalytic system, mechanism and stereoselectivity.
This review carefully summarizes the advances achieved in catalytic hydrofunctionalization of ynamides and is categorized by the bond formation type including C−C, C−X, C−O, C−N, C−S, C−P, C−Si, and C−Ge bonds.
Synthetic potential of ynamides and ynamide-derived advanced intermediates in cycloaddition reactions with different reaction partners to yield versatile heterocyclic adducts.
Metal-free [2 + 2] and [4 + 2] self-cycloadditions of N-aryl-substituted ynamides provide various valuable functionalized aminocyclobutenes and 4-aminoquinoline derivatives.
This review summarizes the latest trends and developments of isoxazole-enabled alkyne amination reactions and their applications in divergent heterocycle synthesis.