This review carefully summarizes the advances achieved in catalytic hydrofunctionalization of ynamides and is categorized by the bond formation type including C−C, C−X, C−O, C−N, C−S, C−P, C−Si, and C−Ge bonds.
Synthetic potential of ynamides and ynamide-derived advanced intermediates in cycloaddition reactions with different reaction partners to yield versatile heterocyclic adducts.
This review provides an overview of skipped dienes synthesis in the last five years. Metal-mediated, metal-free, synergistic/dual and metallaphotoredox catalysed reactions are analysed based on catalytic system, mechanism and stereoselectivity.
A straightforward and sustainable approach for the 1,2-addition of propiolic acids to ynamide has led to bench-stable sp2 (E)-enol-enamides of enediynes and dienynes.
A novel metal-free Brønsted acid-catalyzed Ficini [2 + 2] cycloaddition of ynamides with enones under mild reaction conditions was described.