The main component of polysaccharides from Hippophae rhamnoides L. improves HFD-induced neuronal damage by regulating tryptophan synthesis and metabolism

Abstract

Dietary SPa supplementation improves HFD-induced intestinal barrier damage and neuronal damage in mice via the gut microbiota-tryptophan metabolism-AHR axis.

High GABA-producing Lactococcus lactis ZFM559 and its derived GABA alleviate chronic unpredictable mild stress (CUMS)-induced depression via the “microbiota–brain” axis

Abstract

γ-Aminobutyric acid (GABA) is a crucial inhibitory neurotransmitter with recognized benefits in alleviating depression.

Lactobacillus plantarum AR495 improves colonic transport hyperactivity in irritable bowel syndrome through tryptophan metabolism

Abstract

L. plantarum AR495 could restore the normal levels of 5-HT by inhibiting the abnormal proliferation of enterochromaffin cells and the excessive activation of TPH1 to inhibit the intestinal peristalsis in IBS.

Identification of potential biomarkers for diagnosis of syphilis from the cerebrospinal fluid based on untargeted metabolomic analysis

Abstract

Untargeted metabolomic analysis may promote the development of potential biomarkers for diagnosis of latent syphilis from neurosyphilis, and the early period of neurosyphilis in which symptoms are not apparent from symptomatic neurosyphilis.

Substituted kynurenic acid derivatives as fluorophore-based probes for D- and L-amino acid oxidase assays and their in vitro application in eels

Abstract

Fluorescent probes, 2-MePh-D-KYN and 2-MePh-L-KYN, for detecting D- and L-amino acid oxidase activity, were newly developed respectively. The 2-MePh-D-KYN was successfully applied to detect D-amino acid oxidase activity in eel liver and kidney.

Chapter 9
In Vivo Imaging of the Pancreas and Gut Hormone Receptors