Fariborz Sharifianjazi, Azadeh Jafari Rad, Ameneh Bakhtiari, Firoozeh Niazvand, Amirhossein Esmaeilkhanian, Leila Bazli, Milad Abniki, Mohammad Irani and Amirhossein Moghanian

Biomed. Mater., 2022, 17, 012002
DOI: 10.1088/1748-605X/ac41fd

Glucose-based biofuel cells and their applications in medical implants: A review

Indrani Chakraborty, Richard T. Olsson, Richard L. Andersson and Annu Pandey

Heliyon, 2024, 10, e33615
DOI: 10.1016/j.heliyon.2024.e33615

Manganese‐Based Nanozymes: Preparation, Catalytic Mechanisms, and Biomedical Applications

Minglu Tang, Zhaocong Zhang, Tiedong Sun, Bin Li and Zhiguang Wu

Adv Healthcare Materials, 2022, 11
DOI: 10.1002/adhm.202201733

Selective ATP Detection via Activation of MoS2-Based Artificial Nanozymes Inhibited by ZIF-90 Nanoparticles

Yingwen Wang, Dun Zhang, Yan Zeng and Peng Qi

ACS Appl. Nano Mater., 2021, 4, 11545
DOI: 10.1021/acsanm.1c01986

A review towards sustainable analyte detection: Biomimetic inspiration in biosensor technology

Pratistha Bhagat and Lata Sheo Bachan Upadhyay

Journal of Biotechnology, 2025, 398, 51
DOI: 10.1016/j.jbiotec.2024.11.015

The recent advancements in the early detection of cancer biomarkers by DNAzyme-assisted aptasensors

Hossein Kamali, Shiva Golmohammadzadeh, Hamed Zare, Rahim Nosrati, Mohammad Fereidouni and Hossein Safarpour

J Nanobiotechnol, 2022, 20
DOI: 10.1186/s12951-022-01640-1

Deep Learning-Enhanced Nanozyme-Based Biosensors for Next-Generation Medical Diagnostics

Seungah Lee, Nayra A. M. Moussa and Seong Ho Kang

Biosensors, 2025, 15, 571
DOI: 10.3390/bios15090571

A Novel PCR-Free Ultrasensitive GQD-Based Label-Free Electrochemical DNA Sensor for Sensitive and Rapid Detection of Francisella tularensis

Sumeyra Savas and Melike Sarıçam

Micromachines, 2024, 15, 1308
DOI: 10.3390/mi15111308

Point‐of‐care detection of cytokines in cytokine storm management and beyond: Significance and challenges

Guozhen Liu, Cheng Jiang, Xiaoting Lin and Yang Yang

VIEW, 2021, 2
DOI: 10.1002/VIW.20210003

Highly sensitive electrochemical detection of cholesterol based on Au–Pt NPs/PAMAM–ZIF-67 nanomaterials

Liangtian Zhang, Jianmeng Zhu, Wenzhong Hong and Gang Li

ANAL. SCI., 2024, 40, 37
DOI: 10.1007/s44211-023-00427-0

Modern Electrochemical Biosensing Based on Nucleic Acids and Carbon Nanomaterials

Anna Szymczyk, Robert Ziółkowski and Elżbieta Malinowska

Sensors, 2023, 23, 3230
DOI: 10.3390/s23063230

Highly specific colorimetric detection of sarcosine using surface molecular imprinted Zn/Ce-ZIF

Peng Liu, Yeping Liu, Zhexu Gai, Fei Yang and Yanzhao Yang

Journal of Colloid and Interface Science, 2025, 681, 239
DOI: 10.1016/j.jcis.2024.11.179

Signal-Based Methods in Dielectrophoresis for Cell and Particle Separation

Malihe Farasat, Ehsan Aalaei, Saeed Kheirati Ronizi, Atin Bakhshi, Shaghayegh Mirhosseini, Jun Zhang, Nam-Trung Nguyen and Navid Kashaninejad

Biosensors, 2022, 12, 510
DOI: 10.3390/bios12070510

The Future of Nanotechnology-Driven Electrochemical and Electrical Point-of-Care Devices and Diagnostic Tests

Rabah Boukherroub and Sabine Szunerits

Annual Review of Analytical Chemistry, 2024, 17, 173
DOI: 10.1146/annurev-anchem-061622-012029

Recent progress in the integrating of smartphone-based biosensors with nanozymes for biomedical analysis

Sofiene Mansouri, Yousef Alharbi, Abdulrahman Alqahtani, Nizar Rokbani and Javeed Shaikh Mohammed

Microchemical Journal, 2025, 211, 113093
DOI: 10.1016/j.microc.2025.113093

Nanozyme-mediated cascade reaction system for ratiometric fluorescence detection of sarcosine

Wang Li, Tingting Li, Siqi Chen, Donglian Deng, Yibing Ji and Ruijun Li

Sensors and Actuators B: Chemical, 2022, 355, 131341
DOI: 10.1016/j.snb.2021.131341

An integrated centrifugal microfluidic system for automatic nanozyme ELISA lateral flow immunoassay at point-of-care testing

Yingyi Huang, Lei Wang, Jiaxi Zhou, Guijun Miao, Lulu Zhang, Michael G. Mauk, Lizeng Gao and Xianbo Qiu

Microfluid Nanofluid, 2025, 29
DOI: 10.1007/s10404-025-02812-9

Exploring the Advanced Synthesis Strategies and Biomedical Applications of Iron Oxide-Based Nanozymes: A Comprehensive Review

Tanawish, Nazish Jahan, Kousar Rasheed, Maria Iqbal and Muhammad Atif

J Clust Sci, 2024, 35, 2637
DOI: 10.1007/s10876-024-02690-1

Applications of cerium-based materials in food monitoring

Jiuhong Zhao, Xiaodan Li, Yannan Yin, Ruru Xiong, Guixia Ling and Peng Zhang

Food Chemistry, 2024, 444, 138639
DOI: 10.1016/j.foodchem.2024.138639

Nanozyme-enabled microfluidic biosensors: A promising tool for on-site food safety analysis

Xiru Zhang, Danqing Zhu, Xinyan Yang, Chaoxin Man, Yujun Jiang, Qianyu Zhao and Xianlong Zhang

Trends in Food Science & Technology, 2024, 148, 104486
DOI: 10.1016/j.tifs.2024.104486

Versatile Platinum Nanoparticles-Decorated Phage Nanozyme Integrating Recognition, Bacteriolysis, and Catalysis Capabilities for On-Site Detection of Foodborne Pathogenic Strains Vitality Based on Bioluminescence/Pressure Dual-Mode Bioassay

Hang You, Nannan Ma, Tianhua Li, Zhenzhong Yu and Ning Gan

Anal. Chem., 2024, 96, 8782
DOI: 10.1021/acs.analchem.4c01192

Biomaterials and biosensing technologies in the detection and removal of pesticide residues: Current trends and future prospects

Zhuliang Chen, Ruibing Feng, Qiuzhong Zhou, Xinya Zhang, Yu Fan, Dafeng Fang, Rongbo Zheng, Wei Zhang, Zhaoyang Lu, Jincan Chen, Qing-Wen Zhang, Changlong Jiang, Peng Li, Hua Yu and Guodong Li

Coordination Chemistry Reviews, 2026, 547, 217110
DOI: 10.1016/j.ccr.2025.217110

Electrochemical biosensing methods for analysis of trace biomarkers: a review

Baorong Zhang, Zhuomin Zhang and Gongke Li

Critical Reviews in Analytical Chemistry, 2025, 1
DOI: 10.1080/10408347.2025.2479032

Nucleic acid‐based electrochemical biosensor: Recent advances in probe immobilization and signal amplification strategies

Krishna Thapa, Wenyan Liu and Risheng Wang

WIREs Nanomed Nanobiotechnol, 2022, 14
DOI: 10.1002/wnan.1765

Electrochemical immunosensor based on metal ions functionalized CNSs@Au NPs nanocomposites as signal amplifier for simultaneous detection of triple tumor markers

Lihua Li, Yan Wei, Shengpeng Zhang, Xishan Chen, Taili Shao and Dexiang Feng

Journal of Electroanalytical Chemistry, 2021, 880, 114882
DOI: 10.1016/j.jelechem.2020.114882

Nanoscale materials-based hybrid frameworks modified electrochemical biosensors for early cancer diagnostics: An overview of current trends and challenges

Shreanshi Agrahari, Ravindra Kumar Gautam, Ankit Kumar Singh and Ida Tiwari

Microchemical Journal, 2022, 172, 106980
DOI: 10.1016/j.microc.2021.106980

New advances of nanozymes for the diagnosis and treatment of digestive system diseases (Review)

Daihan Xie, Lixin Xie, Chao Fang, Zhefei Du, Zhenyu Cao, Chunxia Su and Yu Huo

Int J Mol Med, 2025, 56, 1
DOI: 10.3892/ijmm.2025.5617

Plasmonic/magnetic nanoarchitectures: From controllable design to biosensing and bioelectronic interfaces

Yi Chen, Yu Bai, Xi Wang, Heng Zhang, Haoran Zheng and Ning Gu

Biosensors and Bioelectronics, 2023, 219, 114744
DOI: 10.1016/j.bios.2022.114744

Peroxidase Mimetic Nanozymes in Cancer Phototherapy: Progress and Perspectives

Suresh Thangudu and Chia-Hao Su

Biomolecules, 2021, 11, 1015
DOI: 10.3390/biom11071015

Fundamentals of bio-electrochemical sensing

Mahesh M. Shanbhag, G. Manasa, Ronald J. Mascarenhas, Kunal Mondal and Nagaraj P. Shetti

Chemical Engineering Journal Advances, 2023, 16, 100516
DOI: 10.1016/j.ceja.2023.100516

Ultrasmall phosphatase-mimicking nanoceria with slight self-colour for nonredox nanozyme-based colorimetric sensing

Yuhao Xiong, Linjing Su, Fanggui Ye and Shulin Zhao

Analytica Chimica Acta, 2022, 1200, 339604
DOI: 10.1016/j.aca.2022.339604

Recent Advances in Research on Implantable Enzymatic Biofuel Cell

Kang Jin Lee, Phan Gia Le and Moon Il Kim

KSBB, 2021, 36, 238
DOI: 10.7841/ksbbj.2021.36.4.238

Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation

Hanna Lewandowska, Karolina Wójciuk and Urszula Karczmarczyk

Applied Sciences, 2021, 11, 9019
DOI: 10.3390/app11199019

Label-Free Detection of Epinephrine Using Flower-like Biomimetic CuS Antioxidant Nanozymes

Salim Ali, Suranjan Sikdar, Shatarupa Basak, Md Salman Haydar, Kangkan Mallick, Modhusudan Mondal, Debadrita Roy, Shibaji Ghosh, Sanjay Sahu, Paramita Paul and Mahendra Nath Roy

Inorg. Chem., 2023, 62, 11291
DOI: 10.1021/acs.inorgchem.3c00538

Cerium oxide-based hypoxanthine biosensor for Fish spoilage monitoring

Fatima Mustafa, Ali Othman and Silvana Andreescu

Sensors and Actuators B: Chemical, 2021, 332, 129435
DOI: 10.1016/j.snb.2021.129435

Electrochemical Biosensors for Whole Blood Analysis: Recent Progress, Challenges, and Future Perspectives

Shaoguang Li, Hongyuan Zhang, Man Zhu, Zhujun Kuang, Xun Li, Fan Xu, Siyuan Miao, Zishuo Zhang, Xiaoding Lou, Hui Li and Fan Xia

Chem. Rev., 2023, 123, 7953
DOI: 10.1021/acs.chemrev.1c00759

Remote detection of bovine serum albumin (BSA) using cantilever beam magnetometer

Bibhutibhusan Nayak and S. Narayana Jammalamadaka

Journal of Magnetism and Magnetic Materials, 2024, 589, 171537
DOI: 10.1016/j.jmmm.2023.171537

Advances in sepsis diagnosis and management: a paradigm shift towards nanotechnology

Amit Pant, Irene Mackraj and Thirumala Govender

J Biomed Sci, 2021, 28
DOI: 10.1186/s12929-020-00702-6

Ceria-Based Nanozymes in Point-of-Care Diagnosis: An Emerging Futuristic Approach for Biosensing

Ruixue Wang, Yuanyuan Du, Ying Fu, Yingxin Guo, Xing Gao, Xingqi Guo, Jingjing Wei and Yanzhao Yang

ACS Sens., 2023, 8, 4442
DOI: 10.1021/acssensors.3c01692

Vanadium-Based Metal–Organic Frameworks with Peroxidase-like Activity as a Colorimetric Sensing Platform for Direct Detection of Organophosphorus Pesticides

Ningjing Du, Wenchuan Weng, Yuanyuan Xu, Yi Zhou, Yinhui Yi, Yong Zhao and Gangbing Zhu

Inorg. Chem., 2024, 63, 16442
DOI: 10.1021/acs.inorgchem.4c02716

Nanozyme biosensors: Catalytic mechanism, activity regulation, signal amplification and application in food analysis

Xiaonan Ma, Ganchao Sun, Aoxue Leng, Xiaobo Wei, Junnan Xu, Wei Ding, Huiyan Liu and Haitian Fang

Talanta, 2026, 296, 128398
DOI: 10.1016/j.talanta.2025.128398

Surface-enhanced Raman scattering biosensors for detection of oncomiRs in breast cancer

Prachi Chauhan, Arpit Bhargava, Roshani Kumari, Pooja Ratre, Rajnarayan Tiwari, Rupesh Kumar Srivastava, Irina Yu. Goryacheva and Pradyumna Kumar Mishra

Drug Discovery Today, 2022, 27, 2121
DOI: 10.1016/j.drudis.2022.04.016

A critical comparison of natural enzymes and nanozymes in biosensing and bioassays

Amir M. Ashrafi, Zuzana Bytesnikova, Jiri Barek, Lukas Richtera and Vojtech Adam

Biosensors and Bioelectronics, 2021, 192, 113494
DOI: 10.1016/j.bios.2021.113494

Fe, Cu Co-Doped Carbon Nanosheets for Electrochemical-Colorimetric Detection of Acetaminophen

Yi Gao, Tingting Chu, Chengyu Zhou, Wensheng Huang and Yin Zheng

ACS Appl. Nano Mater., 2024, 7, 14321
DOI: 10.1021/acsanm.4c01798

Genetically engineered yeast cells enriched with nanocomposites containing a natural enzyme and nanozyme for the construction of microbial sensors

Nataliya Stasyuk, Andriy Zakalskiy, Wojciech Nogala, Marcin Holdynski, Sylwester Gawinkowski, Oksana Zakalska, Olha Demkiv, Yuriy Salyha and Mykhailo Gonchar

Electrochimica Acta, 2024, 497, 144605
DOI: 10.1016/j.electacta.2024.144605

Synergistically Enhanced Oxidase-like Property of Core–Shell MOF Nanozymes by Decorating Au and Ag/AgCl Nanoparticles for l-Cysteine Colorimetric Sensing

Haoran Li, Daqing Chen, Wen Zhou, Donghao Cheng, Danhua Ge and Xiaojun Chen

Langmuir, 2023, 39, 16833
DOI: 10.1021/acs.langmuir.3c02332

Nanozyme engineering in structurally explicit framework: Design mechanisms and biosensing applications

Yanbin Xu, Anlian Huang, Wei Yi, Guosheng Chen, Siming Huang and Gangfeng Ouyang

Coordination Chemistry Reviews, 2024, 500, 215517
DOI: 10.1016/j.ccr.2023.215517

A Critical Review on Detection of Foodborne Pathogens Using Electrochemical Biosensors

Avinash V. Police Patil, Ping-Feng Yang, Chiou-Ying Yang, M. S. Gaur and Ching-Chou Wu

Crit Rev Biomed Eng, 2024, 52, 17
DOI: 10.1615/CritRevBiomedEng.2023049469

Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration

Amal George Kurian, Rajendra K. Singh, Varsha Sagar, Jung-Hwan Lee and Hae-Won Kim

Nano-Micro Lett., 2024, 16
DOI: 10.1007/s40820-024-01323-6

Surface modification strategies and the functional mechanisms of gold nanozyme in biosensing and bioassay

Sanam Garehbaghi, Amir M. Ashrafi, Vojtěch Adam and Lukáš Richtera

Materials Today Bio, 2023, 20, 100656
DOI: 10.1016/j.mtbio.2023.100656

Application of magnetic nanomaterials in electroanalytical methods: A review

Mazaher Ahmadi, Arash Ghoorchian, Kheibar Dashtian, Mahdie Kamalabadi, Tayyebeh Madrakian and Abbas Afkhami

Talanta, 2021, 225, 121974
DOI: 10.1016/j.talanta.2020.121974

Electrochemical sensors based on metal nanoparticles with biocatalytic activity

Katarzyna Białas, Despina Moschou, Frank Marken and Pedro Estrela

Microchim Acta, 2022, 189
DOI: 10.1007/s00604-022-05252-2

Electrochemical Affinity Biosensors Based on Selected Nanostructures for Food and Environmental Monitoring

Susana Campuzano, Paloma Yáñez-Sedeño and José M. Pingarrón

Sensors, 2020, 20, 5125
DOI: 10.3390/s20185125

Heteroatom-doped nanozyme progress and perspectives: From synthesis strategies to biomedical applications

Yayu Yang, Xinliu Tan, Yiran Wang, Baoxing Shen, Yaqiong Yang and He Huang

Chemical Engineering Journal, 2023, 468, 143703
DOI: 10.1016/j.cej.2023.143703

Applications of Metals and Metal Compounds in Improving the Sensitivity of Microfluidic Biosensors – A Review

Taiyi Zhang, Xuezhen Dong, Xing Gao, Yujing Yang, Weidu Song, Jike Song, Hongsheng Bi, Yurong Guo and Jibin Song

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202400578

Research on the application of metal-organic framework (MOF)-based nanozymes in colorimetric and electrochemical detection of biomolecules

Xingxing Li, Li Fu, Fei Chen, Yanfei Lv, Shichao Zhao and Hassan Karimi-Maleh

Inorganic Chemistry Communications, 2025, 179, 114752
DOI: 10.1016/j.inoche.2025.114752

Bibliometric Analysis and Network Visualization of Nanozymes for Microbial Theranostics in the Last Decade

Hamza Ettadili and Caner Vural

Appl Biochem Biotechnol, 2025, 197, 1923
DOI: 10.1007/s12010-024-05120-0

Nanozymes in electrochemical affinity biosensing

Susana Campuzano, María Pedrero, Paloma Yáñez-Sedeño and José M. Pingarrón

Microchim Acta, 2020, 187
DOI: 10.1007/s00604-020-04390-9

Metalloporphyrin-based Amphiphilic Porous Organic Polymer with Peroxidase-mimetic Activity for Colorimetric Detection of Ascorbic Acid

Lei Liu, Binyu Zhao, Xiaogang Luo, Lingkui Meng and Fengshou Wu

Food Anal. Methods, 2023, 16, 1477
DOI: 10.1007/s12161-023-02519-z

Recent Developments in Nanozyme Based Sensors for Detection of Clinical Biomarkers—A Review

Fareeha Arshad, Damien W. M. Arrigan and Minhaz Uddin Ahmed

IEEE Sensors J., 2022, 22, 15622
DOI: 10.1109/JSEN.2022.3191291

Nano-Analytical Techniques in Pharmaceutical Analysis

C. Hima Bindu, T. Farmaan, K. Aparna, M. Sadan and T Reshma

Jordan j. pharm. sci., 2025, 18, 341
DOI: 10.35516/jjps.v18i2.2631

Pore-Forming Toxin-Driven Recovery of Peroxidase-Mimicking Activity in Biomass Channels for Label-Free Electrochemical Bacteria Sensing

Junjian Zhao, Zirui Wang, Mei Yang, Junli Guo, Zhida Gao, Pei Song and Yan-Yan Song

Anal. Chem., 2024, 96, 7661
DOI: 10.1021/acs.analchem.4c00589

Aspects of Electrochemical Biosensors Using Affinity Assays

Thor Pedersen, Leonid Gurevich and Nils E. Magnusson

Biosensors, 2025, 15, 166
DOI: 10.3390/bios15030166

Multiple recognition elements in biosensors: A review of antibiotic detection technologies

Hai-Meng Lai, Wei Shang, Tian-Xu Duan, Ming-Zhu Ding and Jing-Sheng Cheng

Talanta, 2026, 297, 128764
DOI: 10.1016/j.talanta.2025.128764

Robust Nanozyme-Enzyme Nanosheets-Based Lactate Biosensor for Diagnosing Bacterial Infection in Olive Flounder (Paralichthys olivaceus)

Thenmozhi Rajarathinam, Seonghye Kim, Dinakaran Thirumalai, Sujin Lee, Minho Kwon, Hyun-jong Paik, Suhkmann Kim and Seung-Cheol Chang

Biosensors, 2021, 11, 439
DOI: 10.3390/bios11110439

Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling

Ning Xia, Fengli Gao, Jiwen Zhang, Jiaqiang Wang and Yaliang Huang

Molecules, 2024, 29, 2796
DOI: 10.3390/molecules29122796

Molecular Diagnosis and Cancer Prognosis—A Concise Review

Thatchanamoorthy Thenrajan, Subbiah Alwarappan and Jeyaraj Wilson

Diagnostics, 2023, 13, 766
DOI: 10.3390/diagnostics13040766

Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique

Rana Said, Asma Ghazzy, Ashok K. Shakya and Afnan Al hunaiti

Bioanalysis, 2024, 16, 1261
DOI: 10.1080/17576180.2024.2415779

Optical fiber surface plasmon resonance sensor using electroless-plated gold film for thrombin detection

Yu Huang, Xiaoyin Pu, Husun Qian, Chin-Jung Chuang, Shanshan Dong, Jiangling Wu, Jianjiang Xue, Wei Cheng, Shijia Ding and Shengqiang Li

Anal Bioanal Chem, 2024, 416, 1469
DOI: 10.1007/s00216-024-05150-x

Synthesis, Catalytic Properties and Application in Biosensorics of Nanozymes and Electronanocatalysts: A Review

Nataliya Stasyuk, Oleh Smutok, Olha Demkiv, Tetiana Prokopiv, Galina Gayda, Marina Nisnevitch and Mykhailo Gonchar

Sensors, 2020, 20, 4509
DOI: 10.3390/s20164509

A nanozyme colorimetric sensor combined with cloud-based machine learning algorithm-assisted WeChat mini program for intelligent identification of Chinese green tea

Wanjun Long, Siyu Wang, Yangcheng Ling, Yuting Guan, Huiru Zhang, Hengye Chen, Wei Lan, Yuanbin She and Haiyan Fu

Food Research International, 2025, 214, 116668
DOI: 10.1016/j.foodres.2025.116668

Realizing selective detection with nanozymes: Strategies and trends

Xin Li, Hengjia Zhu, Peng Liu, Mengzhu Wang, Jianming Pan, Fengxian Qiu, Liang Ni and Xiangheng Niu

TrAC Trends in Analytical Chemistry, 2021, 143, 116379
DOI: 10.1016/j.trac.2021.116379

Recent advancements of nanomodified electrodes – Towards point-of-care detection of cardiac biomarkers

Ana Gomez Cardoso, Syed Rahin Ahmed, Zahra Keshavarz-Motamed, Seshasai Srinivasan and Amin Reza Rajabzadeh

Bioelectrochemistry, 2023, 152, 108440
DOI: 10.1016/j.bioelechem.2023.108440

Ovarian Cancer: Potential biomarkers and nanotechnology based diagnostic tools

Shruti Sounkaria and Prakash Chandra

Adv. Nat. Sci: Nanosci. Nanotechnol., 2021, 12, 033001
DOI: 10.1088/2043-6262/ac2741

Catalytic Nanoparticles in Biomedical Applications: Exploiting Advanced Nanozymes for Therapeutics and Diagnostics

Divinah Manoharan, Liu‐Chun Wang, Ying‐Chi Chen, Wei‐Peng Li and Chen‐Sheng Yeh

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202400746

Exploring Nucleic Acid Nanozymes: A New Frontier in Biosensor Development

Keren Chen, Zaihui Du, Yangzi Zhang, Ruobin Bai, Longjiao Zhu and Wentao Xu

Biosensors, 2025, 15, 142
DOI: 10.3390/bios15030142

Single-atom nanozymes: From bench to bedside

Chanyuan Jin, Sanjun Fan, Zechao Zhuang and Yongsheng Zhou

Nano Res., 2023, 16, 1992
DOI: 10.1007/s12274-022-5060-5

Electrochemical sensors: basic principles, engineering, and state of the art

Heru Agung Saputra

Monatsh Chem, 2023, 154, 1083
DOI: 10.1007/s00706-023-03113-z

Review—Electrochemical Biosensors for Alpha-Fetoprotein Detection: Recent Advances and Future Perspectives

Motahareh Sadat Raziyan, Arvydas Palevicius and Giedrius Janusas

J. Electrochem. Soc., 2024, 171, 077510
DOI: 10.1149/1945-7111/ad586f

“Nanobody-based immunodiagnostics: A systematic review of nanobody integration in diagnostics and deep insight into electrochemical immunoassays”

Mohammad IA. Ahmad, Célia G. Amorim, Luay F. Abu Qatouseh and Maria C.B.S.M. Montenegro

Microchemical Journal, 2024, 196, 109628
DOI: 10.1016/j.microc.2023.109628

The Role of Peptides in the Design of Electrochemical Biosensors for Clinical Diagnostics

Patrick Severin Sfragano, Giulia Moro, Federico Polo and Ilaria Palchetti

Biosensors, 2021, 11, 246
DOI: 10.3390/bios11080246

Bioactive metallic nanozymes-based electrochemical biosensors for biomarker detection: Progress and prospects

Runan Tan, Panpan Jiang, Nan Gao, Zhiwei Cai, Halina Grushevskaya, Yuxiang Wu, Hanping He, Yunbin He and Gang Chang

Nano Materials Science, 2025
DOI: 10.1016/j.nanoms.2024.07.005

Peroxidases and Peroxidase‐Mimicking Capacities of Copper Nanozymes: Catalytic Mechanism, Applications, and Properties‐A Review

Fahimeh Bahramnejad, Mojtaba Mortazavi, Ali Riahi‐Madvar and Mehdi Rahimi

Biotech and App Biochem, 2025
DOI: 10.1002/bab.70035

Recent advances in optical biosensing approaches for biomarkers detection

Semra Akgönüllü and Adil Denizli

Biosensors and Bioelectronics: X, 2022, 12, 100269
DOI: 10.1016/j.biosx.2022.100269

Biomarkers for Cancer: A Detail Review

Ritesh Bhole, Pravin Bhondave, Rupesh Chikhale, Chandrakant Bonde and Shailendra Gurav

Fr. Ukr. J. Chem., 2023, 11, 30
DOI: 10.17721/fujcV11I1P30-59

Microneedle Arrays for Sampling and Sensing Skin Interstitial Fluid

Navid Kashaninejad, Ahmed Munaz, Hajar Moghadas, Sharda Yadav, Muhammad Umer and Nam-Trung Nguyen

Chemosensors, 2021, 9, 83
DOI: 10.3390/chemosensors9040083

A signal “off–on” electrochemical aptamer sensor of Staphylococcus aureus based on ZIF8-derived carbon decorated with platinum nanoparticles

Xiaohua Jiang, Zhiwen Lv, Xiaowen Chen and Changquan Rao

Microchemical Journal, 2025, 209, 112627
DOI: 10.1016/j.microc.2024.112627

Dual-signal readout aptasensor for electrochemical and colorimetric assay using a bifunctional Ni-Fe PBA probe

Yan Huang, Jing Ge, Hao Chen, Zhen Wang, Jing Han, Gang Xie and Sanping Chen

Sensors and Actuators B: Chemical, 2021, 327, 128871
DOI: 10.1016/j.snb.2020.128871

Advances in bimetallic materials and bimetallic oxide nanozymes: Synthesis, classification, catalytic mechanism and application in analytical chemistry

Yun-Yun Wu, Xin Tian, Yuan Jiang, Hao-Yu Ma, Wei Wang, Wen-Sheng Zhang, Jovan San Martin, Yong Yan, Dong-Dong Qin, Dong-Xue Han and Li Niu

TrAC Trends in Analytical Chemistry, 2024, 176, 117757
DOI: 10.1016/j.trac.2024.117757

Perspective for Single Atom Nanozymes Based Sensors: Advanced Materials, Sensing Mechanism, Selectivity Regulation, and Applications

Huan Jin, Daixin Ye, Lihua Shen, Ruixue Fu, Ya Tang, Joey Chung-Yen Jung, Hongbin Zhao and Jiujun Zhang

Anal. Chem., 2022, 94, 1499
DOI: 10.1021/acs.analchem.1c04496

Simple and highly sensitive electrochemical detection of Listeria monocytogenes based on aptamer-regulated Pt nanoparticles/hollow carbon spheres nanozyme activity

Xiaohua Jiang, Zhiwen Lv, Changquan Rao, Xiaowen Chen, Ying Zhang and Feng Lin

Sensors and Actuators B: Chemical, 2023, 392, 133991
DOI: 10.1016/j.snb.2023.133991

Colorimetric and Electrochemical Dual-Mode Detection of Thioredoxin 1 Based on the Efficient Peroxidase-Mimicking and Electrocatalytic Property of Prussian Blue Nanoparticles

Jeong Un Kim, Jee Min Kim, Annadurai Thamilselvan, Ki-Hwan Nam and Moon Il Kim

Biosensors, 2024, 14, 185
DOI: 10.3390/bios14040185

A One-Step Electrochemical Aptasensor Based on Signal Amplification of Metallo Nanoenzyme Particles for Vascular Endothelial Growth Factor

ChenYang Mei, Yuanyuan Zhang, Luting Pan, Bin Dong, Xingwei Chen, Qingyi Gao, Hang Xu, Wenjin Xu, Hui Fang, Siyu Liu, Colm McAlinden, Eleftherios I. Paschalis, Qinmei Wang, Mei Yang, Jinhai Huang and A-Yong Yu

Front. Bioeng. Biotechnol., 2022, 10
DOI: 10.3389/fbioe.2022.850412

Hollow Pt Nanocage@Mesoporous SiO2 Nanoreactors as a Nanozyme for Colorimetric Immunoassays of Viral Diagnosis

Lin Long, Mingji Zong, Yunqing Xie, Qing Chai, Jianbo Liu and Xiaochun Wu

ACS Appl. Nano Mater., 2022, 5, 1553
DOI: 10.1021/acsanm.1c04221

Immobilization of Enzyme Electrochemical Biosensors and Their Application to Food Bioprocess Monitoring

Ganchao Sun, Xiaobo Wei, Dianping Zhang, Liben Huang, Huiyan Liu and Haitian Fang

Biosensors, 2023, 13, 886
DOI: 10.3390/bios13090886

Multimodal/Multifunctional Nanomaterials in (Bio)electrochemistry: Now and in the Coming Decade

Paloma Yáñez-Sedeño, Araceli González-Cortés, Susana Campuzano and José Manuel Pingarrón

Nanomaterials, 2020, 10, 2556
DOI: 10.3390/nano10122556

Nanozyme-based sensors for cancer diagnosis

Olga Guliy and Lev Dykman

Biosensors and Bioelectronics: X, 2024, 19, 100512
DOI: 10.1016/j.biosx.2024.100512

Electrochemical immunosensors based on the solubility difference of electroactive probe and the dual signal amplification of nanocarrier plus redox cycling

Yong Chang, Yajun Wang, Xueqian Fan, Jia Zhou, Yunhe Lv and Ning Xia

Bioelectrochemistry, 2025, 162, 108858
DOI: 10.1016/j.bioelechem.2024.108858

Advances in Metal-organic Frameworks (MOFs) based Biosensors for Diagnosis: An Update

Ghazala Ashraf, Tauqir Ahmad, Muhammad Zeeshan Ahmed, Murtaza and Yousef Rasmi

CTMC, 2022, 22, 2222
DOI: 10.2174/1568026622666220829125548

Biomimetic electrochemical sensors: New horizons and challenges in biosensing applications

Pedro V.V. Romanholo, Claudia A. Razzino, Paulo A. Raymundo-Pereira, Thiago M. Prado, Sergio A.S. Machado and Livia F. Sgobbi

Biosensors and Bioelectronics, 2021, 185, 113242
DOI: 10.1016/j.bios.2021.113242

Recent advances on nanozyme-based electrochemical biosensors for cancer biomarker detection

Annadurai Thamilselvan and Moon Il Kim

TrAC Trends in Analytical Chemistry, 2024, 177, 117815
DOI: 10.1016/j.trac.2024.117815

A universal stimuli-responsive biosensor for disease biomarkers through their cysteine residues: A proof of concept on carcinoembryonic antigen (CEA) biomarker

Mahnaz D. Gholami, Serena Nihal, Qian Liu, Daniel Sarfo, Prashant Sonar and Emad L. Izake

Sensors and Actuators B: Chemical, 2023, 393, 134208
DOI: 10.1016/j.snb.2023.134208

Programming a hollow core-shell CuS@CuSe heteromicrocubes synergizing superior multienzyme activity function as enhanced biosensing platforms

Xiaoqing Ma, Kang-lai Tang, Kang Lu, Binfang Yuan, Wenbing Shi, Yadong Li and Wenxi Zhao

Sensors and Actuators B: Chemical, 2022, 359, 131592
DOI: 10.1016/j.snb.2022.131592

Recent progress on nanozymes in electrochemical sensing

Wenting Wu and Jing Li

Journal of Electroanalytical Chemistry, 2023, 936, 117391
DOI: 10.1016/j.jelechem.2023.117391

“Green” Prussian Blue Analogues as Peroxidase Mimetics for Amperometric Sensing and Biosensing

Galina Z. Gayda, Olha M. Demkiv, Yanna Gurianov, Roman Ya. Serkiz, Halyna M. Klepach, Mykhailo V. Gonchar and Marina Nisnevitch

Biosensors, 2021, 11, 193
DOI: 10.3390/bios11060193

Graphene-Gold Nanoparticles Nanozyme-Based Electrochemical Sensor with Enhanced Laccase-Like Activity for Determination of Phenolic Substrates

Livia Alexandra Dinu Gugoasa, Florina Pogacean, Sevinc Kurbanoglu, Lucian-Barbu Tudoran, Andreea Bianca Serban, Irina Kacso and Stela Pruneanu

J. Electrochem. Soc., 2021, 168, 067523
DOI: 10.1149/1945-7111/ac0c32

A Bioinspired Assembly to Simultaneously Heterogenize Polyoxometalates as Nanozymes and Encapsulate Enzymes in a Microstructure Endowing Efficient Peroxidase-Mimicking Activity

Jayadev Nayak, Rakesh Chilivery, A. Kiran Kumar, Gousia Begum and Rohit Kumar Rana

ACS Sustainable Chem. Eng., 2021, 9, 15819
DOI: 10.1021/acssuschemeng.1c05238

Electropotential-Inspired Star-Shaped Gold Nanoconfined Multiwalled Carbon Nanotubes: A Proof-of-Concept Electrosensoring Interface for Lung Metastasis Biomarkers

Sangya Bhattacharjee, Melvin George, Yoon-Bo Shim, Neppolian Bernaurdshaw and Jayabrata Das

ACS Appl. Bio Mater., 2022, 5, 5567
DOI: 10.1021/acsabm.2c00605

Colorimetric immunosensing using liposome encapsulated MnO2 nanozymes for SARS-CoV-2 antigen detection

Chenchen Chu, Mingyang Jiang, Yun Hui, Yueying Huang, Weijun Kong, Wenting Zhu, Jitao Wei, Lie Wu, Chi Huang, Xue-Feng Yu, Zhen Zhao, Wenhua Zhou, Shengyong Geng and Ling Ji

Biosensors and Bioelectronics, 2023, 239, 115623
DOI: 10.1016/j.bios.2023.115623

Nanozymes towards Personalized Diagnostics: A Recent Progress in Biosensing

Chitra Padmakumari Kurup and Minhaz Uddin Ahmed

Biosensors, 2023, 13, 461
DOI: 10.3390/bios13040461

Self-Assembled Fabrication of Water-Soluble Porphyrin Mediated Supramolecule-Gold Nanoparticle Networks and Their Application in Selective Sensing

Xiaojun Hu, Ruhui Hu, Xueqin Wu, Fengda Songsun, Han Zhu, Jie Chen and Hongxia Chen

Bulletin of the Chemical Society of Japan, 2021, 94, 2662
DOI: 10.1246/bcsj.20210254

Role of Nanozymes in Oral Cancer the Road Ahead

Dominic Augustine, S. V. Sowmya, Neethi Gujjar, C. Pushpalatha and Vanishri C. Haragannavar

Top Catal, 2022, 65, 1973
DOI: 10.1007/s11244-022-01729-9

Porous, Oxygen Vacancy Enhanced CeO2–x Microspheres with Efficient Enzyme-Mimetic and Photothermal Properties

Cagil Zeynep Sungu Akdogan, Burcu Gokcal, Mustafa Polat, Kadriye Ozlem Hamaloglu, Cigdem Kip and Ali Tuncel

ACS Sustainable Chem. Eng., 2022, 10, 9492
DOI: 10.1021/acssuschemeng.2c01981

Monodispersed Au nanoparticles decorated MoS2 nanosheets with enhanced peroxidase-like activity based electrochemical H2O2 sensing for anticancer drug evaluations

Qiwen Liu, Yang Huang, Sheng Wang, Shuo Yang, Zhengjin Jiang and Shengfeng Huang

Analytica Chimica Acta, 2024, 1320, 342996
DOI: 10.1016/j.aca.2024.342996

Machine Learning Enhances the Performance of Bioreceptor-Free Biosensors

Kenneth E. Schackart and Jeong-Yeol Yoon

Sensors, 2021, 21, 5519
DOI: 10.3390/s21165519

Nanohybrid nanozyme based colourimetric immunosensor for porcine gelatin

Fareeha Arshad, Siti Nurul Azian Zakaria and Minhaz Uddin Ahmed

Food Chemistry, 2024, 438, 137947
DOI: 10.1016/j.foodchem.2023.137947

Recent Advances on Nanozyme‐based Electrochemical Biosensors

Xiaoyu Wang, Shaojun Dong and Hui Wei

Electroanalysis, 2023, 35
DOI: 10.1002/elan.202100684

Enhancing the substrate selectivity of enzyme mimetics in biosensing and bioassay: Novel approaches

Amir M. Ashrafi, Atripan Mukherjee, Arezoo Saadati, Frank-Michael Matysik, Lukas Richtera and Vojtech Adam

Advances in Colloid and Interface Science, 2024, 331, 103233
DOI: 10.1016/j.cis.2024.103233

Molecular Imprinting on Nanozymes for Sensing Applications

Ana R. Cardoso, Manuela F. Frasco, Verónica Serrano, Elvira Fortunato and Maria Goreti Ferreira Sales

Biosensors, 2021, 11, 152
DOI: 10.3390/bios11050152

Versatile graphitic nanozymes for magneto actuated cascade reaction-enhanced treatment of S. mutans biofilms

Qian Dong, Zhaoqian Li, Jieqiong Xu, Quan Yuan, Long Chen and Zhuo Chen

Nano Res., 2022, 15, 9800
DOI: 10.1007/s12274-022-4258-x

Smart Sensors in Food Packaging: Sensor Technology for Real‐Time Food Safety and Quality Monitoring

Ranjita Mani, Jothi Vinoth Kumar, Balakrishnan Murugesan, Ramalakshmi Alaguthevar and Jong‐Whan Rhim

J Food Process Engineering, 2025, 48
DOI: 10.1111/jfpe.70120

Gold nanoparticle-graphene quantum dots nanozyme for the wide range and sensitive electrochemical determination of quercetin in plasma droplets

Cristina Stefanov, Catalina Cioates Negut, Livia Alexandra Dinu Gugoasa and Jacobus Frederick van Staden

Microchim Acta, 2020, 187
DOI: 10.1007/s00604-020-04587-y

Nanozymes and Their Application Progress in Biomedical Detection

Feng WEI and Xiao-Jun HAN

Chinese Journal of Analytical Chemistry, 2021, 49, 581
DOI: 10.1016/S1872-2040(21)60092-0

Microwave biosensors utilizing metamaterial enhancement: Design and application

Jiaxu Wang, Rongheng Wang, Zhou Shen, Bohua Liu, Chongling Sun and Qiannan Xue

Nanotechnology and Precision Engineering, 2025, 8
DOI: 10.1063/10.0028757

Synergistic optimization strategies for the development of multienzymatic cascade system-based electrochemical biosensors with enhanced performance

Yuzhuo Zhu, Zhaoming Cheng, Xueqi Wang, Chuanjun Zhang, Xuwen Li, Yanxue Wei, Jiajia Wang, Yuxin Fang, Yi Wang and Di Zhang

Biosensors and Bioelectronics, 2025, 274, 117222
DOI: 10.1016/j.bios.2025.117222

Graphene quantum dot/hydrogel nanozyme composites: a next-generation approach for point-of-care diagnostics and non-destructive biomedical evaluation

Seyyed Mojtaba Mousavi, Masoomeh Yari Kalashgrani, Ahmad Gholami, Muhammad Fazle Rabbee, Vahid Rahmanian, Fatemeh Fallahi Nezhad, Mahmood D. Aljabri, Mohammed Muzibur Rahman and Wei-Hung Chiang

Microchemical Journal, 2025, 216, 114690
DOI: 10.1016/j.microc.2025.114690

Revolutionizing cancer monitoring with carbon-based electrochemical biosensors

Fatemeh Karimi, Hassan Karimi-Maleh, Jalal Rouhi, Najmeh Zare, Ceren Karaman, Mehdi Baghayeri, Li Fu, Sadegh Rostamnia, Elena Niculina Dragoi, Ali Ayati and Pavel Krivoshapkin

Environmental Research, 2023, 239, 117368
DOI: 10.1016/j.envres.2023.117368