Progressive study on ruthenium catalysis for de(hydrogenative) alkylation and alkenylation using alcohols as a sustainable source

Rahul Sharma, Arup Samanta, Bitan Sardar, Mithu Roy and Dipankar Srimani

Org. Biomol. Chem., 2022, 20, 7998
DOI: 10.1039/D2OB01323A

EffectiveN-methylation of nitroarenes with methanol catalyzed by a functionalized NHC-based iridium catalyst: a green approach toN-methyl amines

Miguel González-Lainez, M. Victoria Jiménez, Vincenzo Passarelli and Jesús J. Pérez-Torrente

Catal. Sci. Technol., 2020, 10, 3458
DOI: 10.1039/D0CY00707B

Direct activation of alcohols via perrhenate ester formation for an intramolecular dehydrative Friedel–Crafts reaction

Yuzhu Zheng, Xiong Fang, Wen-Hao Deng, Bin Zhao, Rong-Zhen Liao and Youwei Xie

Org. Chem. Front., 2022, 9, 4277
DOI: 10.1039/D2QO00229A

Lignin-derived guaiacols as platform chemicals for the modular synthesis of 1,2,3,4-tetrahydroquinolines and benzomorpholines

Antonio A. Castillo-Garcia, Jörg Haupenthal, Anna K. H. Hirsch and Katalin Barta

RSC Sustainability, 2025, 3, 4039
DOI: 10.1039/D5SU00151J

Extension of hydrogen borrowing alkylation reactions for the total synthesis of (−)-γ-lycorane

Christopher J. J. Hall, Indi S. Marriott, Kirsten E. Christensen, Aaron J. Day, William R. F. Goundry and Timothy J. Donohoe

Chem. Commun., 2022, 58, 4966
DOI: 10.1039/D2CC01248K

Hydrogenation and N-alkylation of anilines and imines via transfer hydrogenation with homogeneous nickel compounds

G. Eliad Benitez-Medina and Juventino J. García

Dalton Trans., 2019, 48, 17579
DOI: 10.1039/C9DT04111G

Mechanistic insight into the azo radical-promoted dehydrogenation of heteroarene towards N-heterocycles

Amreen K. Bains and Debashis Adhikari

Catal. Sci. Technol., 2020, 10, 6309
DOI: 10.1039/D0CY01008A

Radical condensation between benzylic alcohols and acetamides to form 3-arylpropanamides

Kobra Azizi and Robert Madsen

Chem. Sci., 2020, 11, 7800
DOI: 10.1039/D0SC02948C

State-of-the-art advances in homogeneous molecular catalysis for the Guerbet upgrading of bio-ethanol to fuel-grade bio-butanol

Akshara Bisarya, Lakshay Kathuria, Kanu Das, Eileen Yasmin, Raksh Vir Jasra, Sunil Dhole and Akshai Kumar

Chem. Commun., 2025, 61, 2906
DOI: 10.1039/D4CC05931J

Allylic alcohol synthesis by Ni-catalyzed direct and selective coupling of alkynes and methanol

Herong Chen, Zhijun Zhou and Wangqing Kong

Chem. Sci., 2021, 12, 9372
DOI: 10.1039/D1SC02625A

Vicinal difunctionalization of nitriles: modular construction of N-alkyl amidines and late-stage modification

Zixin Xiang, Simiao Zhang, Ziyi Zhang, Hang Liu, Junqi Wang, Wenwen Chen, Yong Wang and Xiaobing Wan

New J. Chem., 2024, 48, 11834
DOI: 10.1039/D4NJ02051K

Manganese-catalyzed hydrogenation, dehydrogenation, and hydroelementation reactions

Kuhali Das, Satyadeep Waiba, Akash Jana and Biplab Maji

Chem. Soc. Rev., 2022, 51, 4386
DOI: 10.1039/D2CS00093H

A phosphine-free iron complex-catalyzed synthesis of cycloalkanesviathe borrowing hydrogen strategy

Léo Bettoni, Sylvain Gaillard and Jean-Luc Renaud

Chem. Commun., 2020, 56, 12909
DOI: 10.1039/D0CC05840H

Nickel-catalyzed alkylation of ketones and nitriles with primary alcohols

Sertaç Genç, Burcu Arslan, Derya Gülcemal, Süleyman Gülcemal and Salih Günnaz

Org. Biomol. Chem., 2022, 20, 9753
DOI: 10.1039/D2OB01787C

A green and sustainable catalytic protocol for methoxymethylation of primary amides using methanol with dihydrogen release

Reshma Babu, Ganesan Sivakumar, Smruti Rekha Padhy and Ekambaram Balaraman

Green Chem., 2025, 27, 2230
DOI: 10.1039/D4GC05864J

Divergence in CH alkylation of indoles under Mn catalysis

Akash Mondal, Rohit Kumar, Abhijith Karattil Suresh, Manoj Kumar Sahoo and Ekambaram Balaraman

Catal. Sci. Technol., 2023, 13, 5745
DOI: 10.1039/D3CY01044A

Nickel-catalyzed coupling of R2P(O)Me (R = aryl or alkoxy) with (hetero)arylmethyl alcohols

Wei-Ze Li and Zhong-Xia Wang

Org. Biomol. Chem., 2021, 19, 2233
DOI: 10.1039/D1OB00086A

Cyano-borrowing: titanium-catalyzed direct amination of cyanohydrins with amines and enantioselective examples

Tang-Lin Liu, Zhao-Feng Li, Jing Tao, Qing-Hua Li, Wan-Fang Li, Qian Li, Li-Qing Ren and Yun-Gui Peng

Chem. Commun., 2020, 56, 651
DOI: 10.1039/C9CC08576A

α-Alkylation of arylacetonitriles with primary alcohols catalyzed by backbone modified N-heterocyclic carbene iridium(i) complexes

Burcu Arslan and Süleyman Gülcemal

Dalton Trans., 2021, 50, 1788
DOI: 10.1039/D0DT04082G

Unveiling the catalytic nature of palladium-N-heterocyclic carbene catalysts in the α-alkylation of ketones with primary alcohols

Mamajan Ovezova, Zafer Eroğlu, Önder Metin, Bekir Çetinkaya and Süleyman Gülcemal

Dalton Trans., 2021, 50, 10896
DOI: 10.1039/D1DT01704G

Mn-catalyzed ring-opening and alkylation of epoxides with alcohols for accessing β-alkylated secondary alcohols via borrowing hydrogen

Qiang Rong, Hongbin Deng, Nan Sun, Anqi Che, Xinquan Hu and Liqun Jin

Org. Chem. Front., 2024, 11, 7107
DOI: 10.1039/D4QO01188K

Redox-neutral dehydrogenative cross-coupling of alcohols and amines enabled by nickel catalysis

Zijuan Yan, Feipeng Liu, Xuchao Wang, Qing Qiang, Yongjie Li, Yao Zhang and Zi-Qiang Rong

Org. Chem. Front., 2022, 9, 1703
DOI: 10.1039/D2QO00004K

Double dehydrogenative coupling of amino alcohols with primary alcohols under Mn(i) catalysis

Ganesan Sivakumar, Abhijith Karattil Suresh, Smruti Rekha Padhy and Ekambaram Balaraman

Chem. Commun., 2024, 60, 13606
DOI: 10.1039/D4CC03595J

Synthesis of N-alkylated amines via alcohol dehydrogenation catalyzed by a bis-azo-diamido coordinated ruthenium(iii) complex

Supriyo Halder, Srijita Naskar, Sampad Malik, Dipika Roy and Kausikisankar Pramanik

Dalton Trans., 2025, 54, 14331
DOI: 10.1039/D5DT01716E

Development and mechanistic investigation of the dehydrogenation of alcohols with an iron(iii) salen catalyst

Nicolai S. B. Hansen, Fabrizio Monda, Frederik Simonsen Bro, Xiyue Liu, Mårten S. G. Ahlquist and Robert Madsen

Org. Biomol. Chem., 2023, 21, 4794
DOI: 10.1039/D3OB00466J

Strategies and mechanisms of metal–ligand cooperativity in first-row transition metal complex catalysts

Matthew R. Elsby and R. Tom Baker

Chem. Soc. Rev., 2020, 49, 8933
DOI: 10.1039/D0CS00509F

A heteroditopic NHC and phosphine ligand supported ruthenium(ii)-complex: an effective catalyst for the N-alkylation of amides using alcohols

S. N. R. Donthireddy, Vivek Kumar Singh and Arnab Rit

Catal. Sci. Technol., 2022, 12, 4050
DOI: 10.1039/D2CY00544A

Mechanistic and machine learning insights into borrowing hydrogen reactions catalyzed by transition metal complexes with N-heterocyclic ligands

Hui-Qi Mo and Cheng Hou

Org. Chem. Front., 2025, 12, 6902
DOI: 10.1039/D5QO01139F

Four- and five-coordinate nickel(ii) complexes bearing new diphosphine–phosphonite and triphosphine–phosphite ligands: catalysts for N-alkylation of amines

Dipankar Panigrahi, Munmun Mondal, Rohit Gupta and Ganesan Mani

RSC Adv., 2022, 12, 4510
DOI: 10.1039/D1RA08961G

Nickel-catalyzed C-alkylation of thioamide, amides and esters by primary alcohols through a hydrogen autotransfer strategy

Peng Yang, Xiuhua Wang, Yu Ma, Yaxin Sun, Li Zhang, Jieyu Yue, Kaiyue Fu, Jianrong Steve Zhou and Bo Tang

Chem. Commun., 2020, 56, 14083
DOI: 10.1039/D0CC06468H

Nickel-catalyzed C3-alkylation of indoles with alcohols via a borrowing hydrogen strategy

Miao Hu, Yong Jiang, Nan Sun, Baoxiang Hu, Zhenlu Shen, Xinquan Hu and Liqun Jin

New J. Chem., 2021, 45, 10057
DOI: 10.1039/D1NJ01581H

Synthesis of imines from the coupling reaction of alcohols and amines catalyzed by phosphine-free cobalt(ii) complexes

Jharna Mahato, Partha Sarathi Bera and Tanmoy Kumar Saha

Org. Biomol. Chem., 2024, 22, 4528
DOI: 10.1039/D4OB00351A

Transfer-dehydrogenation of secondary alcohols catalyzed by manganese NNN-pincer complexes

Svenja Budweg, Kathrin Junge and Matthias Beller

Chem. Commun., 2019, 55, 14143
DOI: 10.1039/C9CC07337J

Design of chiral ferrocenylphosphine-spiro phosphonamidite ligands for ruthenium-catalyzed highly enantioselective coupling of 1,2-diols with amines

Xiao Yi, Yirui Chen, An Huang, Dingguo Song, Jiaying He, Fei Ling and Weihui Zhong

Org. Chem. Front., 2021, 8, 6830
DOI: 10.1039/D1QO01443A

Unsymmetrical triazolyl-naphthyridinyl-pyridine bridged highly active copper complexes supported on reduced graphene oxide and their application in water

Wenkang Hu, Yilin Zhang, Haiyan Zhu, Dongdong Ye and Dawei Wang

Green Chem., 2019, 21, 5345
DOI: 10.1039/C9GC02086A

Nickel-catalyzed borrowing hydrogen annulations: access to diversified N-heterocycles

Peng Yang, Caili Zhang, Wen-Chao Gao, Yu Ma, Xiuhua Wang, Li Zhang, Jieyu Yue and Bo Tang

Chem. Commun., 2019, 55, 7844
DOI: 10.1039/C9CC03975A

Synthesizing carbonyl furan derivatives by a dehydrogenative coupling reaction

Xinyan Li, Xiulan Shao, Xiaoyu Zhang, Qiaoyue Zhao, Hongtao Lai, Bing Cui, Zhihui Shao and Mingqin Zhao

Org. Biomol. Chem., 2022, 20, 6542
DOI: 10.1039/D2OB01130A

N-coordinated Ru(ii) catalyzed solvent freeN-alkylation of primary amines with alcohols through borrowing hydrogen strategy

Bhavya Patel, Rishi Ranjan, Nimesh R. Chauhan, Suman Mukhopadhyay, Angshuman Roy Choudhury and Komal M. Vyas

New J. Chem., 2023, 47, 8305
DOI: 10.1039/D3NJ00210A

Ruthenium-catalysed isomerisation–methylenation of allyl alcohols with methanol: a one-pot synthesis of substituted pyridines

Priyabrata Biswal, Sanu Siyad Pullarat, Shaikh Samser, Basava Punna Rao Aradhyula, Vadapalli Chandrasekhar and Krishnan Venkatasubbaiah

Org. Biomol. Chem., 2025, 23, 6931
DOI: 10.1039/D5OB00881F

Cobalt-catalyzed alkylation of methyl-substituted N-heteroarenes with primary alcohols: direct access to functionalized N-heteroaromatics

Anju Mishra, Ambikesh D. Dwivedi, Sujan Shee and Sabuj Kundu

Chem. Commun., 2020, 56, 249
DOI: 10.1039/C9CC08448G

Synthesis and structure of Pd(ii) pincer complexes: catalytic application in β-alkylation of secondary alcohols involving sequential dehydrogenation of alcohols via the borrowing hydrogen approach

Sekar Pranesh Kavin and Rengan Ramesh

Dalton Trans., 2023, 52, 10038
DOI: 10.1039/D3DT01628E

Discovering the role of N-heterocyclic carbene as hydrogen borrowing organocatalyst: metal-free, directN-alkylation of amines with benzyl alcohols

Richa Sharma, Abdul Rahaman T A, Janmejaya Sen, Irina V. Mashevskaya and Sandeep Chaudhary

Org. Chem. Front., 2023, 10, 730
DOI: 10.1039/D2QO01522F

A hydrogen borrowing annulation strategy for the stereocontrolled synthesis of saturated aza-heterocycles

Anna E. R. Chamberlain, Kieran J. Paterson, Roly J. Armstrong, Heather C. Twin and Timothy J. Donohoe

Chem. Commun., 2020, 56, 3563
DOI: 10.1039/D0CC00903B

Efficient β-alkylation of secondary alcohols to α-substituted ketones catalyzed by functionalized Ir complexes via borrowing hydrogen in water

Xin Liu, Wen-Zhe Dong, Yang Li, Xiaoqiang Yu, Wan-Hui Wang, Yuichiro Himeda and Ming Bao

Org. Chem. Front., 2023, 10, 355
DOI: 10.1039/D2QO01541B

Water as a solvent: transition metal catalyzed dehydrogenation of alcohols going green

Ishani Borthakur, Saloni Kumari and Sabuj Kundu

Dalton Trans., 2022, 51, 11987
DOI: 10.1039/D2DT01060G

Enantioconvergent transformations of secondary alcohols through borrowing hydrogen catalysis

Yaru Gao, Guorong Hong, Bin-Miao Yang and Yu Zhao

Chem. Soc. Rev., 2023, 52, 5541
DOI: 10.1039/D3CS00424D

Blue-light induced iron-catalyzed chemoselective α-alkylation and α-olefination of arylacetonitriles with alcohols

Dingguo Song, Shiliang Wang, Weiwei Huang, Rong Chen, Fangyuan Hu, Lingxin Cheng, Xianghua Zhao, Fei Ling and Weihui Zhong

Org. Chem. Front., 2023, 10, 5908
DOI: 10.1039/D3QO01220D

Highly dispersed ruthenium capsulated in UiO-66-NH2 for hydrogen-borrowing-mediated N-alkylation reactions

Jiahao Li, Shiguo Ou, Xinxin Sang, Ruirui Chai and Dawei Wang

Catal. Sci. Technol., 2024, 14, 1958
DOI: 10.1039/D4CY00161C

Reaction condition controlled nickel(ii)-catalyzed C–C cross-coupling of alcohols

Meng-Juan Zhang, Hong-Xi Li, David J. Young, Hai-Yan Li and Jian-Ping Lang

Org. Biomol. Chem., 2019, 17, 3567
DOI: 10.1039/C9OB00418A

Transition metal-catalysis in interrupted borrowing hydrogen strategy

Madhu Nallagangula, Murugan Subaramanian, Rohit Kumar and Ekambaram Balaraman

Chem. Commun., 2023, 59, 7847
DOI: 10.1039/D3CC01517C

Manganese complex-catalysed α-alkylation of ketones with secondary alcohols enables the synthesis of β-branched carbonyl compounds

Satyadeep Waiba, Sayan K. Jana, Ayan Jati, Akash Jana and Biplab Maji

Chem. Commun., 2020, 56, 8376
DOI: 10.1039/D0CC01460E

Nickel-catalysed chemoselective C-3 alkylation of indoles with alcohols through a borrowing hydrogen method

Amreen K. Bains, Ayanangshu Biswas and Debashis Adhikari

Chem. Commun., 2020, 56, 15442
DOI: 10.1039/D0CC07169B

PPh3-Mediated cascade reaction of 2-alkynylnitrobenzenes and 1,2-diaminoarenes for the construction of 2-aryl-3-(2-aminoaryl)quinoxalines

Xiaoming Liao, Yao Xu, Hui Fan, Xuechun Zhao, Wenjun Wang, Zhuoran Yang and Xiaoxiang Zhang

New J. Chem., 2024, 48, 733
DOI: 10.1039/D3NJ04336C

Computational mechanistic studies of ruthenium catalysed methanol dehydrogenation

Felix J. de Zwart, Vivek Sinha, Monica Trincado, Hansjörg Grützmacher and Bas de Bruin

Dalton Trans., 2022, 51, 3019
DOI: 10.1039/D1DT04168A

Transformation of PET-derived 1,4-benzenedimethanol to make useful alcohols

Chandrika Ghosh, Raymundo Marcial-Hernandez, Matthew J. Andrews and Amit Kumar

RSC Adv., 2025, 15, 21424
DOI: 10.1039/D5RA03609G

An NNN Pd(ii) pincer complex with 1,1-diaminoazine: a versatile catalyst for acceptorless dehydrogenative coupling reactions

Aabid A. Wani, Shivkanya Madhavrao Bhujbal, Deekey Sherpa, Deepika Kathuria, Sumit S. Chourasiya, Subash C. Sahoo and Prasad V. Bharatam

Org. Biomol. Chem., 2025, 23, 343
DOI: 10.1039/D4OB01576B

Recent advances in C/N-alkylation with alcohols through hydride transfer strategies

Mahdi Jafarzadeh, Seyed Hasan Sobhani, Karol Gajewski and Ebrahim Kianmehr

Org. Biomol. Chem., 2022, 20, 7713
DOI: 10.1039/D2OB00706A

Recent advances in sustainable synthesis of N-heterocycles following acceptorless dehydrogenative coupling protocol using alcohols

Milan Maji, Dibyajyoti Panja, Ishani Borthakur and Sabuj Kundu

Org. Chem. Front., 2021, 8, 2673
DOI: 10.1039/D0QO01577F

Copper–cobalt coordination polymers and catalytic applications on borrowing hydrogen reactions

Shaoze Chang, Hongqiang Liu, Gang Shi, Xiao-Feng Xia, Dawei Wang and Zheng-Chao Duan

New J. Chem., 2022, 46, 15929
DOI: 10.1039/D2NJ01763F

A strategic approach for Csp3–H functionalization of 9H-fluorene: an acceptorless dehydrogenation and borrowing hydrogen approach

Rahul Sharma, Avijit Mondal, Arup Samanta and Dipankar Srimani

Catal. Sci. Technol., 2023, 13, 611
DOI: 10.1039/D2CY02060B

Biorenewable carbon-supported Ru catalyst for N-alkylation of amines with alcohols and selective hydrogenation of nitroarenes

Vishakha Goyal, Naina Sarki, Mukesh Kumar Poddar, Anand Narani, Deependra Tripathi, Anjan Ray and Kishore Natte

New J. Chem., 2021, 45, 14687
DOI: 10.1039/D1NJ01654G

Tandem transformations and multicomponent reactions utilizing alcohols following dehydrogenation strategy

Bhaskar Paul, Milan Maji, Kaushik Chakrabarti and Sabuj Kundu

Org. Biomol. Chem., 2020, 18, 2193
DOI: 10.1039/C9OB02760B

Divergent upgrading pathways of sulfones with primary alcohols: nickel-catalyzed α-alkylation under N2 and metal-free promoted β-olefination in open air

Haiping Yu, Kaiyue Fu, Guang Yang, Mengyu Liu, Peng Yang and Tao Liu

Chem. Commun., 2023, 59, 615
DOI: 10.1039/D2CC05882K

A practical catalytic reductive amination of carboxylic acids

Emma L. Stoll, Thomas Tongue, Keith G. Andrews, Damien Valette, David J. Hirst and Ross M. Denton

Chem. Sci., 2020, 11, 9494
DOI: 10.1039/D0SC02271C

Historical perspective on ruthenium-catalyzed hydrogen transfer and survey of enantioselective hydrogen auto-transfer processes for the conversion of lower alcohols to higher alcohols

Eliezer Ortiz, Jonathan Z. Shezaf, Weijia Shen and Michael J. Krische

Chem. Sci., 2022, 13, 12625
DOI: 10.1039/D2SC05621F

Facile access to 1,2-disubstituted benzimidazoles and 2,3-dihydro-1H-perimidines using a biogenically synthesized single phase δ-MnO2 NP catalyst and its dye removal study

Nandini R., Thrilokraj R., Umesh A. Kshirsagar, Rajeev V. Hegde, Arnab Ghosh, Siddappa A. Patil, Jan Grzegorz Malecki and Ramesh B. Dateer

New J. Chem., 2024, 48, 1327
DOI: 10.1039/D3NJ03803C

Iron-catalysed alkylation of 2-methyl and 4-methyl azaarenes with alcohols via C–H bond activation

Lalit Mohan Kabadwal, Sourajit Bera and Debasis Banerjee

Chem. Commun., 2020, 56, 4777
DOI: 10.1039/D0CC01593H

Ruthenium-catalysed N-alkylation of anilines with primary carbohydrate alcohols via borrowing hydrogen strategy

Kouki Tsuge, Shunnichi Kubota, Kana Sakamoto, Kenji Kitayama and Takahiro Nishimura

Chem. Commun., 2023, 59, 7052
DOI: 10.1039/D3CC01931D

NNN manganese complex-catalyzed α-alkylation of methyl ketones using alcohols: an experimental and computational study

Sachin Jalwal, Anitta Regina, Vaishnavi Atreya, Manikandan Paranjothy and Subrata Chakraborty

Dalton Trans., 2024, 53, 3236
DOI: 10.1039/D3DT04321E

B(C6F5)3-Catalyzed redox-neutral β-alkylation of tertiary amines using p-quinone methides via borrowing hydrogen

Rui Li, Yong Chen, Kun Jiang, Feiyi Wang, Cuifen Lu, Junqi Nie, Zuxing Chen, Guichun Yang, Ying-Chun Chen, Yu Zhao and Chao Ma

Chem. Commun., 2019, 55, 1217
DOI: 10.1039/C8CC09215J

Electroactivated alkylation of amines with alcohols via both direct and indirect borrowing hydrogen mechanisms

Benjamin Appiagyei, Souful Bhatia, Gabriela L. Keeney, Troy Dolmetsch and James E. Jackson

Green Chem., 2020, 22, 860
DOI: 10.1039/C9GC03747K

Ligand-redox assisted nickel catalysis toward stereoselective synthesis of (n+1)-membered cycloalkanes from 1,n-diols with methyl ketones

Amreen K. Bains, Abhishek Kundu, Debabrata Maiti and Debashis Adhikari

Chem. Sci., 2021, 12, 14217
DOI: 10.1039/D1SC04261K

‘Green’ synthesis of amines from renewable resources? A detailed analysis of case studies using the CHEM21 green metrics toolkit

Anastasiia M. Afanasenko, Noemi Deak, Jacquin October, Roberto Sole and Katalin Barta

Green Chem., 2025, 27, 5947
DOI: 10.1039/D5GC00924C

Nickel(i)-catalyzed (de)hydrogenative coupling of amines and alkyl heteroarenes with alcohols

Chunyan Zhang, Qianqian Liang, Wei Yang, Guohui Zhang, Maolin Hu and Guoying Zhang

Green Chem., 2022, 24, 7368
DOI: 10.1039/D2GC02206K

Hydrogen autotransfer with alcohols for alkylations

Nicolas Joly, Sylvain Gaillard, Albert Poater and Jean-Luc Renaud

Org. Chem. Front., 2024, 11, 7278
DOI: 10.1039/D4QO01626B

Rhodium catalysed C-3/5 methylation of pyridines using temporary dearomatisation

Alexandru Grozavu, Hamish B. Hepburn, Elliot P. Bailey, Peter J. Lindsay-Scott and Timothy J. Donohoe

Chem. Sci., 2020, 11, 8595
DOI: 10.1039/D0SC02759F

A general and expedient amination of alcohols catalysed by a single-site (NN)Co(ii)-bidentate complex under solventless conditions

Rohit Kumar, Ankit Kumar Srivastava, Palaniyappan Nagarasu, Vedichi Madhu and Ekambaram Balaraman

Catal. Sci. Technol., 2024, 14, 98
DOI: 10.1039/D3CY00809F

Recent advances in nickel-catalyzed C–C and C–N bond formation via HA and ADC reactions

Murugan Subaramanian, Ganesan Sivakumar and Ekambaram Balaraman

Org. Biomol. Chem., 2021, 19, 4213
DOI: 10.1039/D1OB00080B

Quinoline-derived NNP-manganese complex catalyzed α-alkylation of ketones with primary alcohols

Peidong Song, Haojie Rong, Tingting Meng, Zhe Cui, Mingzhen Mao and Cuifeng Yang

Org. Biomol. Chem., 2024, 22, 5112
DOI: 10.1039/D4OB00827H

Ruthenium catalyzed α-methylation of sulfones with methanol as a sustainable C1 source

Dingguo Song, Linlin Chen, Yujin Li, Tao Liu, Xiao Yi, Lei Liu, Fei Ling and Weihui Zhong

Org. Chem. Front., 2021, 8, 120
DOI: 10.1039/D0QO01171A

Using the Colloidal Method to Prepare Au Catalysts for the Alkylation of Aniline by Benzyl Alcohol

Luka V. Hare, Firdaus Parveen, James Cookson, Peter R. Ellis, Klaus Hellgardt and King Kuok (Mimi) Hii

IJMS, 2023, 24, 14779
DOI: 10.3390/ijms241914779

Efficient and Practical Transfer Hydrogenation of Ketones Catalyzed by a Simple Bidentate Mn−NHC Complex

Robbert van Putten, Joeri Benschop, Vincent J. de Munck, Manuela Weber, Christian Müller, Georgy A. Filonenko and Evgeny A. Pidko

ChemCatChem, 2019, 11, 5232
DOI: 10.1002/cctc.201900882

Triflic Acid‐Catalyzed Dehydrative Amination of 2‐Arylethanols with Weak N‐Nucleophiles in Hexafluoroisopropanol

Max Van Hoof, Robert J. Mayer, Joseph Moran and David Lebœuf

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202417089

Phosphine‐Free Manganese(II)‐Catalyst Enables Acceptorless Dehydrogenative Coupling of Alcohols with Indoles

Vinita Yadav, Ekambaram Balaraman and Santosh B. Mhaske

Adv Synth Catal, 2021, 363, 4430
DOI: 10.1002/adsc.202100621

Ruthenium-Catalyzed Regioselective Synthesis of C3-Alkylated Indoles Following Transfer Hydrogenation or Borrowing Hydrogen Strategy

Xia Chen and Xiao-Yu Zhou

Synthesis, 2023, 55, 1460
DOI: 10.1055/a-2003-3207

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Christopher J. J. Hall, William R. F. Goundry and Timothy J. Donohoe

Angewandte Chemie, 2021, 133, 7057
DOI: 10.1002/ange.202100922

Acyclic Quaternary Carbon Stereocenters through Transition-Metal-Catalyzed Enantioselective Functionalization of Unsaturated Hydrocarbons

Xin Sun and Bi-Jie Li

Synthesis, 2022, 54, 2103
DOI: 10.1055/s-0040-1719899

Recent advances in the catalytic N-methylation and N-trideuteromethylation reactions using methanol and deuterated methanol

Vishakha Goyal, Naina Sarki, Anand Narani, Ganesh Naik, Kishore Natte and Rajenahally V. Jagadeesh

Coordination Chemistry Reviews, 2023, 474, 214827
DOI: 10.1016/j.ccr.2022.214827

Reductive Alkylation of Azides and Nitroarenes with Alcohols: A Selective Route to Mono- and Dialkylated Amines

Ishani Borthakur, Milan Maji, Abhisek Joshi and Sabuj Kundu

J. Org. Chem., 2022, 87, 628
DOI: 10.1021/acs.joc.1c02625

Theoretical study of Ni(0)-catalyzed intermolecular hydroamination of branched 1,3-dienes: reaction mechanism, regioselectivity, enantioselectivity, and prediction of the ligand

Fen Wang, Changbao Chen, Feng Zhang and Qingxi Meng

J Mol Model, 2025, 31
DOI: 10.1007/s00894-024-06217-3

Efficient Synthesis of C3‐Alkylated and Alkenylated Indoles via Manganese‐Catalyzed Dehydrogenation

Mingqin Zhao, Xinyan Li, Xiaoyu Zhang and Zhihui Shao

Chemistry An Asian Journal, 2022, 17
DOI: 10.1002/asia.202200483

Iridium-, Ruthenium-, and Nickel-Catalyzed C–C Couplings of Methanol, Formaldehyde, and Ethanol with π-Unsaturated Pronucleophiles via Hydrogen Transfer

Cole C. Meyer and Michael J. Krische

J. Org. Chem., 2023, 88, 4965
DOI: 10.1021/acs.joc.2c02356

A Short Synthesis of Ergot Alkaloids and Evaluation of the 5-HT1/2 Receptor Selectivity of Lysergols and Isolysergols

Nikhil R. Tasker and Peter Wipf

Org. Lett., 2022, 24, 7255
DOI: 10.1021/acs.orglett.2c02569

Ligand‐Promoted [Pd]‐Catalyzed α‐Alkylation of Ketones through a Borrowing‐Hydrogen Approach

Seetharaman Manojveer, Nitish K. Garg, Zarif Gul, Ayesha Kanwal, Yogesh Goriya and Magnus T. Johnson

ChemistryOpen, 2023, 12
DOI: 10.1002/open.202200245

Iron-Catalyzed Acceptorless Dehydrogenative Coupling of Alcohols With Aromatic Diamines: Selective Synthesis of 1,2-Disubstituted Benzimidazoles

Ramachandra Reddy Putta, Simin Chun, Seok Beom Lee, Dong-Chan Oh and Suckchang Hong

Front. Chem., 2020, 8
DOI: 10.3389/fchem.2020.00429

Iron-Catalyzed Transfer Hydrogenation of Allylic Alcohols with Isopropanol

Md Abdul Bari, Salma A. Elsherbeni, Tahir Maqbool, Daniel E. Latham, Edward B. Gushlow, Emily J. Harper and Louis C. Morrill

J. Org. Chem., 2024, 89, 14571
DOI: 10.1021/acs.joc.4c01701

Manganese-Catalyzed Synthesis of Polyketones Using Hydrogen-Borrowing Approach

Pavel S. Kulyabin, Oxana V. Magdysyuk, Aaron B. Naden, Daniel M. Dawson, Ketan Pancholi, Matthew Walker, Massimo Vassalli and Amit Kumar

ACS Catal., 2024, 14, 10624
DOI: 10.1021/acscatal.4c03019

First‐Row Transition‐Metal Catalyzed Acceptorless Dehydrogenation and Related Reactions: A Personal Account

Murugan Subaramanian, Ganesan Sivakumar and Ekambaram Balaraman

The Chemical Record, 2021, 21, 3839
DOI: 10.1002/tcr.202100165

Synthesis and Single-Crystal X-ray Structures of Sterically Hindered Three Half-Sandwich (η6-p-Cymene)ruthenium(II) Schiff Base Complexes: Catalytic Applications in Selective Monoalkylation of Amines and Synthesis of Amides

Bhumika Agrahari, Samaresh Layek, Rakesh Ganguly and Devendra Deo Pathak

Organometallics, 2025, 44, 1951
DOI: 10.1021/acs.organomet.5c00221

Multi‐Step Reactions Involving Iron‐Catalysed Reduction and Hydrogen Borrowing Reactions

Duo Wei, Chakkrit Netkaew and Christophe Darcel

Eur J Inorg Chem, 2019, 2019, 2471
DOI: 10.1002/ejic.201900122

Direct Synthesis of Cycloalkanes from Diols and Secondary Alcohols or Ketones Using a Homogeneous Manganese Catalyst

Akash Kaithal, Lisa-Lou Gracia, Clément Camp, Elsje Alessandra Quadrelli and Walter Leitner

J. Am. Chem. Soc., 2019, 141, 17487
DOI: 10.1021/jacs.9b08832

Zn(II)-Catalyzed Selective N-Alkylation of Amines with Alcohols Using Redox Noninnocent Azo-Aromatic Ligand as Electron and Hydrogen Reservoir

Subhajit Chakraborty, Rakesh Mondal, Subhasree Pal, Amit Kumar Guin, Lisa Roy and Nanda D. Paul

J. Org. Chem., 2023, 88, 771
DOI: 10.1021/acs.joc.2c01773

Manganese-Catalyzed C(α)-Alkylation of Oxindoles with Secondary Alcohols via Borrowing Hydrogen

Jagannath Rana, Palaniyappan Nagarasu, Murugan Subaramanian, Akash Mondal, Vedichi Madhu and Ekambaram Balaraman

Organometallics, 2021, 40, 627
DOI: 10.1021/acs.organomet.1c00009

Selective Monoalkylation or Dialkylation of Indenes with Alcohols by Bis-N-Heterocyclic Carbene Manganese

Ning Wang, Yinwu Li, Zhe Chen, Cunyuan Zhao and Zhuofeng Ke

ACS Catal., 2024, 14, 18032
DOI: 10.1021/acscatal.4c05200

Catalytic Acceptorless Dehydrogenation of Amino Alcohols and 2-Hydroxybenzyl Alcohols for Annulation Reaction under Neutral Conditions

Akanksha M. Pandey, Naveen Kumar Digrawal, Nirmala Mohanta, Akash Bandu Jamdade, Moreshwar B. Chaudhari, Girish Singh Bisht and Boopathy Gnanaprakasam

J. Org. Chem., 2021, 86, 8805
DOI: 10.1021/acs.joc.1c00714

Heterogeneously catalyzed direct cross-coupling of secondary alcohols to β-disubstituted ketones by Cu/γ-Al2O3

Jie Jiang and Yuqiang Ding

Inorganica Chimica Acta, 2022, 534, 120830
DOI: 10.1016/j.ica.2022.120830

Interception of Nickel Hydride Species and Its Application in Multicomponent Reactions

Venkadesh Balakrishnan, Anirban Ganguly and Ramesh Rasappan

Org. Lett., 2022, 24, 4804
DOI: 10.1021/acs.orglett.2c01862

A Proton‐Responsive Pyridyl(benzamide)‐Functionalized NHC Ligand on Ir Complex for Alkylation of Ketones and Secondary Alcohols

Mandeep Kaur, Noor U Din Reshi, Kamaless Patra, Arindom Bhattacherya, Sooraj Kunnikuruvan and Jitendra K. Bera

Chemistry A European J, 2021, 27, 10737
DOI: 10.1002/chem.202101360

Manganese‐Catalyzed One‐Pot Conversion of Nitroarenes into N‐Methylarylamines Using Methanol

Benjamin G. Reed‐Berendt, Nicolas Mast and Louis C. Morrill

Eur J Org Chem, 2020, 2020, 1136
DOI: 10.1002/ejoc.201901854

Iron‐Catalyzed N‐Alkylation of Secondary Amines with Alcohols Using Borrowing Hydrogen Strategy

Ruxin Qu, Yaxuan Cheng, Siwei Yang, Chaoyu Zhao, Huiling Liu and Xuri Huang

ChemistrySelect, 2021, 6, 4089
DOI: 10.1002/slct.202100712

Anti‐Markovnikov Hydroamination of Racemic Allylic Alcohols to Access Chiral γ‐Amino Alcohols

Ruirui Xu, Kun Wang, Haoying Liu, Weijun Tang, Huaming Sun, Dong Xue, Jianliang Xiao and Chao Wang

Angew Chem Int Ed, 2020, 59, 21959
DOI: 10.1002/anie.202009754

Ruthenium(0)-Mediated Successive N–H and S–H/C–H Bond Activation in Selected Imine Ligands: Elucidation of the Activation Mechanism and Application in Borrowing Hydrogen Catalysis

Anushri Chandra, Satyaki Kundu, Papu Dhibar, Anannya Saha, Piyali Paul and Samaresh Bhattacharya

Inorg. Chem., 2026, 65, 36
DOI: 10.1021/acs.inorgchem.5c02501

Exploring the Potential of a Non-Phosphine Cobalt System for Alcohol Activation: Expedition of C–C and C–N Bond Formation

Rahul Sharma, Kailash Mohar, Avijit Mondal, Elinda Basumatary, Kaushik Soni and Dipankar Srimani

Organometallics, 2025, 44, 2172
DOI: 10.1021/acs.organomet.5c00206

Formal Deoxygenative Hydrogenation of Lactams Using PNHP-Pincer Ruthenium Complexes under Nonacidic Conditions

Osamu Ogata, Hideki Nara, Kazuhiko Matsumura and Yoshihito Kayaki

Org. Lett., 2019, 21, 9954
DOI: 10.1021/acs.orglett.9b03878

Intermolecular Stereospecific Substitution of Underivatized Enantioenriched Secondary Alcohols by Organocatalysis

Sunisa Akkarasamiyo and Joseph S. M. Samec

Angew Chem Int Ed, 2019, 58, 17908
DOI: 10.1002/anie.201911532

Single-Molecular Mn(I)-Complex-Catalyzed Tandem Double Dehydrogenation Cross-Coupling of (Amino)Alcohols under Solventless Conditions with the Liberation of H2 and H2O

Ganesan Sivakumar, Murugan Subaramanian and Ekambaram Balaraman

ACS Sustainable Chem. Eng., 2022, 10, 7362
DOI: 10.1021/acssuschemeng.2c01222

Recent developments in transition metal-catalyzed asymmetric borrowing hydrogen catalysis

Nidhi Garg, Ishika Agrawal, Dhananjay Satav, Doppalapudi Vineet Kumar and Basker Sundararaju

Tetrahedron Chem, 2023, 8, 100054
DOI: 10.1016/j.tchem.2023.100054

NNN-Pd(II) Pincer Complex Catalyzed Acceptorless Dehydrogenative Coupling and Borrowing Hydrogen Transformations via Metal–Ligand Cooperativity (Nitrene–Imide) in Fluorene Functionalization

Shivkanya M. Bhujbal, Aabid A. Wani and Prasad V. Bharatam

Organometallics, 2025, 44, 2592
DOI: 10.1021/acs.organomet.5c00385

Iron-Catalyzed sp3 C–H Alkylation of Fluorene with Primary and Secondary Alcohols: A Borrowing Hydrogen Approach

Ratnakar Saha, Bhairab Chand Hembram, Surajit Panda, Rahul Ghosh and Bidraha Bagh

J. Org. Chem., 2024, 89, 16223
DOI: 10.1021/acs.joc.4c00819

Iridium and bis(4-nitrophenyl)phosphoric acid catalysed amination of diol by hydrogen-borrowing methodology for the synthesis of cyclic amine: Synthesis of clopidogrel

Sharada Prasanna Swain, Om Shri and V. Ravichandiran

Molecular Catalysis, 2021, 508, 111576
DOI: 10.1016/j.mcat.2021.111576

Half-Sandwich Iridium Complexes with Hydrazone Ligands: Synthesis and Catalytic Activity in N-Alkylation of Anilines or Nitroarenes with Alcohols via Hydrogen Autotransfer

Yang Wang, Fang-Lei Zhang, Zhen-Jiang Liu and Zi-Jian Yao

Inorg. Chem., 2022, 61, 10310
DOI: 10.1021/acs.inorgchem.2c00703

Catalytic Properties of Pd Deposited on Polyaniline in the Hydrogenation of Quinoline

Olena O. Kompaniiets, Vladyslav V. Subotin, Andrii S. Poturai, Aleksandr A. Yurchenko, Alina A. Gorlova, Igor B. Bychko, Igor Ye. Kotenko, Olena O. Pariiska, Serhiy V. Ryabukhin, Dmytro M. Volochnyuk and Sergey V. Kolotilov

Chemistry, 2024, 6, 738
DOI: 10.3390/chemistry6040044

Switchable Access to Amines and Imines from Reductive Coupling of Nitroarenes with Alcohols Catalyzed by Biomass-Derived Cobalt Nanoparticles

Tao Song, Yanan Duan, Xiufang Chen and Yong Yang

Catalysts, 2019, 9, 116
DOI: 10.3390/catal9020116

Manganese(I)-Catalyzed Sustainable Synthesis of Quinoxaline and Quinazoline Derivatives with the Liberation of Dihydrogen

Akash Mondal, Manoj Kumar Sahoo, Murugan Subaramanian and Ekambaram Balaraman

J. Org. Chem., 2020, 85, 7181
DOI: 10.1021/acs.joc.0c00561

Nickel-Catalyzed Alkylation of Ketone Enolates: Synthesis of Monoselective Linear Ketones

Jagadish Das, Mari Vellakkaran and Debasis Banerjee

J. Org. Chem., 2019, 84, 769
DOI: 10.1021/acs.joc.8b02609

Ru(II)-NHC catalysed N-Alkylation of amines with alcohols under solvent-free conditions

Emine Özge Karaca, Zieneb Imene Dehimat, Sedat Yaşar, Nevin Gürbüz, Dahmane Tebbani, Bekir Çetinkaya and İsmail Özdemir

Inorganica Chimica Acta, 2021, 520, 120294
DOI: 10.1016/j.ica.2021.120294

NNN Palladium(II)Pincer Complex in a Borrowing Hydrogen Process: Alkylation of Indoles

Shivkanya M. Bhujbal, Aabid A. Wani and Prasad V. Bharatam

Eur J Org Chem, 2025, 28
DOI: 10.1002/ejoc.202500313

Cobalt-catalyzed chemoselective alkenylation and alkylation of C(sp3)–H bond in methyl heteroarenes

Baoying Zhu, Haitao Tian, Zhaolun Zhang, Ting Li, Lingbo Qu and Conghui Tang

Journal of Catalysis, 2024, 435, 115569
DOI: 10.1016/j.jcat.2024.115569

Mono‐N‐Alkylation of Sulfonamides with Alcohols Catalyzed by Iridium N‐Heterocyclic Carbene‐Phosphine Complexes

Xingzhen Li, Bram B. C. Peters, Min Tan, Lei He, Jianping Yang, Pher G. Andersson and Taigang Zhou

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202200178

Ni(II)-Complex Anchored onto Magnetically Separable Oxidized Single-Walled Carbon Nanohorn: A DFT-Supported Mechanistic Approach for Hydrogen-Borrowing Quinoxaline Synthesis

Sneha Biswas, Tania Chowdhury, Soumadip Banerjee, Koushik Dutta, Abhijit K. Das and Debasis Das

ACS Sustainable Chem. Eng., 2023, 11, 14734
DOI: 10.1021/acssuschemeng.3c03680

Selective C- and N-Methylation of Secondary Alcohols and Nitroaromatics with Methanol Catalyzed by a New Ru(II)-Azo Complex

Santana Chakraborty, Subhankar Khanra, Sreekanta Dutta, Paula Brandão and Nanda D. Paul

Organometallics, 2024, 43, 2714
DOI: 10.1021/acs.organomet.4c00148

Sustainable and Selective Alkylation of Deactivated Secondary Alcohols to Ketones by Non‐bifunctional Pincer N‐heterocyclic Carbene Manganese

Xiao‐Bing Lan, Zongren Ye, Jiahao Liu, Ming Huang, Youxiang Shao, Xiang Cai, Yan Liu and Zhuofeng Ke

ChemSusChem, 2020, 13, 2557
DOI: 10.1002/cssc.202000576

Selective Synthesis of Bisdimethylamine Derivatives from Diols and an Aqueous Solution of Dimethylamine through Iridium‐Catalyzed Borrowing Hydrogen Pathway

Jaeyoung Jeong and Ken‐ichi Fujita

ChemCatChem, 2022, 14
DOI: 10.1002/cctc.202101499

A Protic Mn(I) Complex Based on a Naphthyridine-N-oxide Scaffold: Protonation/Deprotonation Studies and Catalytic Applications for Alkylation of Ketones

Kamaless Patra, Roshayed Ali Laskar, Anubhav Nath and Jitendra K. Bera

Organometallics, 2022, 41, 1836
DOI: 10.1021/acs.organomet.2c00085

Alcohol Dehydrogenation Catalyzed by Azo‐Oxime Coordinated Ruthenium(II): A Strategic and Sustainable Route towards Site‐Selective C(sp3)–H Functionalization of 9H‐Fluorene

Srijita Naskar, Supriyo Halder, Aritra Das, Sampad Malik, Gopal Kanrar, Debashis Jana, Bikash Kumar Panda, Kausikisankar Pramanik and Sanjib Ganguly

Asian J Org Chem, 2025, 14
DOI: 10.1002/ajoc.202500330

Manganese‐Catalyzed Mono‐N‐Methylation of Aliphatic Primary Amines without the Requirement of External High‐Hydrogen Pressure

Jiale Ji, Yinghao Huo, Zhaowen Dai, Zhening Chen and Tao Tu

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202318763

Direct synthesis of partially ethoxylated branched polyethylenimine from ethanolamine

Claire N. Brodie, Alister S. Goodfellow, Matthew J. Andrews, Aniekan E. Owen, Michael Bühl and Amit Kumar

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-50403-z

Manganese‐Triazolylidene Catalysis for The Synthesis of 1,2,3,4‐Tetrahydroquinoxalines and Selective Alkylation of Diamines and Anilines with Alcohols and Diols

Beatriz Garcia, Sofia Friães, Daniel Raydan, M. Manuel B. Marques and Beatriz Royo

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202500113

Diastereo- and Enantioselective Construction of Spirocycles by Nickel-Catalyzed Cascade Borrowing Hydrogen Cyclization

Zhengtian Ding, Yiming Wang, Wenfeng Liu, Yate Chen and Wangqing Kong

J. Am. Chem. Soc., 2021, 143, 53
DOI: 10.1021/jacs.0c10055

Palladium-catalyzed chemoselective N-monoallylation of aromatic amines with diallylamine through a borrowing hydrogen strategy

Chengcheng Fang, Jie-Qing Ou, Xiaoye Mo, Yingqian Xu and Sifeng Li

Tetrahedron, 2025, 179, 134648
DOI: 10.1016/j.tet.2025.134648

C-Alkylation of Various Carbonucleophiles with Secondary Alcohols under CoIII-Catalysis

Priyanka Chakraborty, Nidhi Garg, Eric Manoury, Rinaldo Poli and Basker Sundararaju

ACS Catal., 2020, 10, 8023
DOI: 10.1021/acscatal.0c01728

N-Alkylation of Amines by C1–C10 Aliphatic Alcohols Using A Well-Defined Ru(II)-Catalyst. A Metal–Ligand Cooperative Approach

Amit Kumar Guin, Subhasree Pal, Subhajit Chakraborty, Santana Chakraborty and Nanda D. Paul

J. Org. Chem., 2023, 88, 5944
DOI: 10.1021/acs.joc.3c00313

Hydrogenation of C=N bonds on TiO2 surface: The effect of the Cu2O/TiO2 p-n heterojunction photocatalyst

Jie Jiang and Yuqiang Ding

Surfaces and Interfaces, 2023, 37, 102625
DOI: 10.1016/j.surfin.2022.102625

Ruthenium NNN‐Based Pincer Complexes with Metal Ligand Cooperation as Catalysts for N‐Methylation of Anilines and Nitroarenes with Methanol as a C1 Source

Nitish K. Garg, Yogesh Goriya, Seetharaman Manojveer, Ola F. Wendt and Magnus T. Johnson

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202301601

Iron-Catalyzed Anti-Markovnikov Hydroamination and Hydroamidation of Allylic Alcohols

Wei Ma, Xiaohui Zhang, Juan Fan, Yuxuan Liu, Weijun Tang, Dong Xue, Chaoqun Li, Jianliang Xiao and Chao Wang

J. Am. Chem. Soc., 2019, 141, 13506
DOI: 10.1021/jacs.9b05221

Mechanistic Complexity of Asymmetric Transfer Hydrogenation with Simple Mn–Diamine Catalysts

Robbert van Putten, Georgy A. Filonenko, Angela Gonzalez de Castro, Chong Liu, Manuela Weber, Christian Müller, Laurent Lefort and Evgeny Pidko

Organometallics, 2019, 38, 3187
DOI: 10.1021/acs.organomet.9b00457

Synthesis of functionalized pyrimidouracils by ruthenium‐catalyzed oxidative insertion of (hetero)aryl methanols into N‐uracil amidines

Pradip Debnath, Gouranga Sahu and Utpal C. De

Applied Organom Chemis, 2021, 35
DOI: 10.1002/aoc.6087

Terpenylation of Ketones and a Secondary Alcohol under Hydrogen-Borrowing Manganese Catalysis

Sachin Jalwal, Sourajit Das and Subrata Chakraborty

J. Org. Chem., 2025, 90, 309
DOI: 10.1021/acs.joc.4c02260

Iridium(I)-Catalyzed C–C and C–N Bond Formation Reactions via the Borrowing Hydrogen Strategy

Sertaç Genç, Burcu Arslan, Süleyman Gülcemal, Salih Günnaz, Bekir Çetinkaya and Derya Gülcemal

J. Org. Chem., 2019, 84, 6286
DOI: 10.1021/acs.joc.9b00632

Co‐Catalyzed Metal‐Ligand Cooperative Approach for N‐alkylation of Amines and Synthesis of Quinolines via Dehydrogenative Alcohol Functionalization

Sucheta Mondal, Subhasree Pal, Subhankar Khanra, Santana Chakraborty and Nanda D. Paul

Eur J Inorg Chem, 2023, 26
DOI: 10.1002/ejic.202300263

Manganese-Catalyzed α-Olefination of Nitriles with Secondary Alcohols

Vinita Yadav, Vinod G. Landge, Murugan Subaramanian and Ekambaram Balaraman

ACS Catal., 2020, 10, 947
DOI: 10.1021/acscatal.9b02811

Theoretical investigations of Co-catalyzed allylic aminations

Qingxi Meng and Fen Wang

Molecular Catalysis, 2024, 564, 114342
DOI: 10.1016/j.mcat.2024.114342

Pd supported Al-BDC MOF for efficient and selective N-methylation of amines under solventless conditions

Manjot Kaur, Ashutosh Sharma, Yadvinder Singh, Avtar Singh, Harpreet Kaur, Sanjeev Kumar, Sandeep Kaushal and Rahul Badru

emergent mater., 2024, 7, 1683
DOI: 10.1007/s42247-024-00669-2

Photocatalytic Deoxygenative Alkylation with Alcohols via Xanthates or Thionocarbonates

Wei Luo, Zhong Chen and Bing Yu

Asian J Org Chem, 2025, 14
DOI: 10.1002/ajoc.202400627

Dynamic Kinetic Resolution Allows Control of Remote Stereochemistry in Asymmetric Hydrogen Borrowing Alkylation

Daniella M. J. Cheang, Jessica L. Crompton, Mostafa M. Amer, Francisco Battiti, Bastian Bjerkem Skjelstad, Kirsten E. Christensen, Peter Barton, Fernanda Duarte and Timothy J. Donohoe

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202424959

Recent developments in transition metal catalyzed acceptorless dehydrogenation of amines and N–heterocycles

P.K. Raziya Shaheen and Abir Sarbajna

Coordination Chemistry Reviews, 2026, 547, 217095
DOI: 10.1016/j.ccr.2025.217095

New Access Routes to Privileged and Chiral Ligands for Transition‐Metal Catalyzed Hydrogen Autotransfer (Borrowing Hydrogen), Dehydrogenative Condensation, and Alkene Isomerization Reactions

Sebastian Koller, Philippe Klein, Katja Reinhardt, Lukas Ochmann, Antonia Seitz, Christian Jandl, Alexander Pöthig and Lukas Hintermann

Helvetica Chimica Acta, 2021, 104
DOI: 10.1002/hlca.202100175

Cooperative Reactivity of Methylene‐Linked Bis‐Triazolylidene Ligands in Tungsten‐Catalyzed Alcohol Dehydrogenation

Beatriz Garcia, Maria Batuecas and Beatriz Royo

ChemistryEurope, 2026, 4
DOI: 10.1002/ceur.202500456

Catalytic N-Alkylation of Anilines

A. R. Bayguzina and R. I. Khusnutdinov

Russ J Gen Chem, 2021, 91, 305
DOI: 10.1134/S1070363221030014

Nickel-Catalyzed Kumada Vinylation of Enol Phosphates: A Comparative Mechanistic Study

Philippe-Alexandre Poisson, Gaël Tran, Céline Besnard and Clément Mazet

ACS Catal., 2021, 11, 15041
DOI: 10.1021/acscatal.1c04800

Hydrogen‐Borrowing‐Based Methods for the Construction of Quaternary Stereocentres

Jessica L. Crompton, Timothy C. Jenkins, Sam M. Rowe and Timothy J. Donohoe

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202423179

Anti‐Markovnikov Hydroamination of Racemic Allylic Alcohols to Access Chiral γ‐Amino Alcohols

Ruirui Xu, Kun Wang, Haoying Liu, Weijun Tang, Huaming Sun, Dong Xue, Jianliang Xiao and Chao Wang

Angewandte Chemie, 2020, 132, 22143
DOI: 10.1002/ange.202009754

Manganese‐Catalyzed Mono‐N‐Methylation of Aliphatic Primary Amines without the Requirement of External High‐Hydrogen Pressure

Jiale Ji, Yinghao Huo, Zhaowen Dai, Zhening Chen and Tao Tu

Angew Chem Int Ed, 2024, 63
DOI: 10.1002/anie.202318763

A Microwave-Assisted SmI2-Catalyzed Direct N-Alkylation of Anilines with Alcohols

Jitendra Gour, Srikanth Gatadi, Satyaveni Malasala, Madhavi Venkata Yaddanpudi and Srinivas Nanduri

J. Org. Chem., 2019, 84, 7488
DOI: 10.1021/acs.joc.9b00717

Ruthenium-Catalyzed Formal Hydroamination of Allyl Alcohols to γ-Amino Alcohols via a Borrowing Hydrogen Process

Mengxuan Bai, Xuetong Zhang, Shengxin Zhang, Caicai Zhang, Zhiqiang Hao and Jin Lin

J. Org. Chem., 2025, 90, 13957
DOI: 10.1021/acs.joc.5c02071

Mechanistic Study of Metal–Ligand Cooperativity in Mn(II)-Catalyzed Hydroborations: Hemilabile SNS Ligand Enables Metal Hydride-Free Reaction Pathway

Matthew R. Elsby, Mina Son, Changjin Oh, Jessica Martin, Mu-Hyun Baik and R. Tom Baker

ACS Catal., 2021, 11, 9043
DOI: 10.1021/acscatal.1c02238

Bidentate geometry-constrained iminopyridyl nickel-catalyzed synthesis of amines or imines via borrowing hydrogen or dehydrogenative condensation

Yong Jiang, Miao Hu, Nan Sun, Baoxiang Hu, Zhenlu Shen, Xinquan Hu and Liqun Jin

Tetrahedron Letters, 2020, 61, 152604
DOI: 10.1016/j.tetlet.2020.152604

Earth‐abundant Metal‐catalyzed Reductive Amination: Recent Advances and Prospect for Future Catalysis

Jianguo Liu, Yanpei Song and Longlong Ma

Chemistry An Asian Journal, 2021, 16, 2371
DOI: 10.1002/asia.202100473

CO to Isonitrile Substitution in Iron Cyclopentadienone Complexes: A Class of Active Iron Catalysts for Borrowing Hydrogen Strategies

Gaëtan Quintil, Léa Diebold, Gibrael Fadel, Jacques Pécaut, Christian Philouze, Martin Clémancey, Geneviève Blondin, Ragnar Bjornsson, Adrien Quintard and Amélie Kochem

ACS Catal., 2024, 14, 7795
DOI: 10.1021/acscatal.4c01506

Ligand-Free Ru-Catalyzed Direct sp3 C–H Alkylation of Fluorene Using Alcohols

Moseen A. Shaikh, Sandip G. Agalave, Akash S. Ubale and Boopathy Gnanaprakasam

J. Org. Chem., 2020, 85, 2277
DOI: 10.1021/acs.joc.9b02913

Dehydrogenative amide synthesis from alcohols and amines utilizing N-heterocyclic carbene-based ruthenium complexes as efficient catalysts: The influence of catalyst loadings, ancillary and added ligands

Wan-Qiang Wang, Zhi-Qin Wang, Wei Sang, Rui Zhang, Hua Cheng, Cheng Chen and Da-Yong Peng

Polyhedron, 2021, 195, 114979
DOI: 10.1016/j.poly.2020.114979

Atomically Dispersed Ru Catalyst Locked in Knitting Aryl Network Polymers: A Robust Heterogeneous Catalyst for Borrowing Hydrogenation in Aqueous Micelles

Tanupriya Singh, Rajan Yadav and Susanta Hazra

ACS Appl. Mater. Interfaces, 2025, 17, 52024
DOI: 10.1021/acsami.5c09711

On the Use of Iron in Organic Chemistry

Arnar Guðmundsson and Jan-E. Bäckvall

Molecules, 2020, 25, 1349
DOI: 10.3390/molecules25061349

Fe‐Catalyzed Amidation of Allylic Alcohols by Borrowing Hydrogen Catalysis

Xiaoyun Wu, Wei Ma, Weijun Tang, Dong Xue, Jianliang Xiao and Chao Wang

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202201829

Iron Complexes of 4,5-Bis(diorganophosphinomethyl)acridine Ligands

Maximilian Roca Jungfer, Frank Rominger, Thomas Oeser, Emilia Götz, A. Stephen K. Hashmi and Thomas Schaub

Inorg. Chem., 2024, 63, 18655
DOI: 10.1021/acs.inorgchem.4c02409

Carbon Dioxide Hydrogenation to Formate Catalyzed by a Neutral, Coordinatively Saturated Tris‐Carbonyl Mn(I)‐PNP Pincer‐Type Complex

Sylwia Kostera, Gabriele Manca and Luca Gonsalvi

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202302642

Redox surrogate methods for sustainable amine N-alkylation

Rebecca E Ruscoe, Jeremy I Ramsden and Nicholas J Turner

Current Opinion in Chemical Engineering, 2020, 30, 60
DOI: 10.1016/j.coche.2020.08.005

Bis-Triazolylidenes of Manganese and Rhenium and Their Catalytic Application in N-Alkylation of Amines with Alcohols

Sofia Friães, Clara S. B. Gomes and Beatriz Royo

Organometallics, 2023, 42, 1803
DOI: 10.1021/acs.organomet.3c00046

Methanol as the Hydrogen Source in the Selective Transfer Hydrogenation of Alkynes Enabled by a Manganese Pincer Complex

Jan Sklyaruk, Viktoriia Zubar, Jannik C. Borghs and Magnus Rueping

Org. Lett., 2020, 22, 6067
DOI: 10.1021/acs.orglett.0c02151

Synthesis of α-Alkylated Ketones via Selective Epoxide Opening/Alkylation Reactions with Primary Alcohols

Sertaç Genç, Süleyman Gülcemal, Salih Günnaz, Bekir Çetinkaya and Derya Gülcemal

Org. Lett., 2021, 23, 5229
DOI: 10.1021/acs.orglett.1c01765

β‐Arylation of Racemic Secondary Benzylic Alcohols to Access Enantioenriched β‐Arylated Alcohols

Wang Miao, Jinyu Zhang, Yanyan Yang, Weijun Tang, Dong Xue, Jianliang Xiao, Huaming Sun and Chao Wang

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202306015

Carbonyl Allylation and Crotylation: Historical Perspective, Relevance to Polyketide Synthesis, and Evolution of Enantioselective Ruthenium-Catalyzed Hydrogen Auto-Transfer Processes

Eliezer Ortiz, Connor Saludares, Jessica Wu, Yoon Cho, Catherine G. Santana and Michael J. Krische

Synthesis, 2023, 55, 1487
DOI: 10.1055/s-0042-1751420

Chromium‐Catalyzed Alkylation of Amines by Alcohols

Fabian Kallmeier, Robin Fertig, Torsten Irrgang and Rhett Kempe

Angew Chem Int Ed, 2020, 59, 11789
DOI: 10.1002/anie.202001704

Iron-Catalyzed Hydrogen Transfer Reduction of Nitroarenes with Alcohols: Synthesis of Imines and Aza Heterocycles

Jiajun Wu and Christophe Darcel

J. Org. Chem., 2021, 86, 1023
DOI: 10.1021/acs.joc.0c02505

Applications of imino-pyridine Ni(II) complexes as catalysts in the transfer hydrogenation of ketones

Nokwanda Tsaulwayo, Robert.T. Kumah and Stephen.O. Ojwach

Journal of Molecular Structure, 2021, 1232, 129987
DOI: 10.1016/j.molstruc.2021.129987

Sequential Catalytic Modification of the Lignin α-Ethoxylated β-O-4 Motif To Facilitate C–O Bond Cleavage by Ruthenium-Xantphos Catalyzed Hydrogen Transfer

Zhenlei Zhang, Ciaran W. Lahive, Douwe S. Zijlstra, Zhiwen Wang and Peter. J. Deuss

ACS Sustainable Chem. Eng., 2019
DOI: 10.1021/acssuschemeng.9b01193

O-Acetyl 1,3-Propanediol as an Acrolein Proelectrophile in Enantioselective Iridium-Catalyzed Carbonyl Allylation

Katherine L. Verboom, Cole C. Meyer, Madeline M. Evarts, Woo-Ok Jung and Michael J. Krische

Org. Lett., 2023, 25, 3659
DOI: 10.1021/acs.orglett.3c01022

Asymmetric Guerbet Reaction to Access Chiral Alcohols

Kun Wang, Lin Zhang, Weijun Tang, Huaming Sun, Dong Xue, Ming Lei, Jianliang Xiao and Chao Wang

Angew Chem Int Ed, 2020, 59, 11408
DOI: 10.1002/anie.202003104

Divergent Synthesis of Pyrazoles via Manganese Pincer Complex Catalyzed Acceptorless Dehydrogenative Coupling Reactions

Koushik Sarkar, Pramod Kumar, Arjun Mule and Biplab Maji

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202401105

Ligand-controlled phosphine-free Co(II)-catalysed cross-coupling of secondary and primary alcohols

Shi-Qi Zhang, Bin Guo, Ze Xu, Hong-Xi Li, Hai-Yan Li and Jian-Ping Lang

Tetrahedron, 2019, 75, 130640
DOI: 10.1016/j.tet.2019.130640

Iron‐Based Multi‐Catalysis: Eco‐Compatible Alternative for Complex Molecules Synthesis

Adrien Quintard

Chemistry A European J, 2021, 27, 89
DOI: 10.1002/chem.202002092

Modeling the alkylation of amines with alkyl bromides: explaining the low selectivity due to multiple alkylation

Luis F. Resende and Josefredo R. Pliego

J Mol Model, 2024, 30
DOI: 10.1007/s00894-024-05902-7

Borrowing hydrogen amination: Whether a catalyst is required?

Andrey S. Kozlov, Oleg I. Afanasyev and Denis Chusov

Journal of Catalysis, 2022, 413, 1070
DOI: 10.1016/j.jcat.2022.08.014

Recent advances in Co-catalyzed C–C and C–N bond formation via ADC and ATH reactions

Meng-Juan Zhang, Xiao-Lan Ge, David J. Young and Hong-Xi Li

Tetrahedron, 2021, 93, 132309
DOI: 10.1016/j.tet.2021.132309

Ru-Catalyzed Selective Catalytic Methylation and Methylenation Reaction Employing Methanol as the C1 Source

Nandita Biswas and Dipankar Srimani

J. Org. Chem., 2021, 86, 10544
DOI: 10.1021/acs.joc.1c01185

Nonbifunctional Outer-Sphere Strategy Achieved Highly Active α-Alkylation of Ketones with Alcohols by N-Heterocyclic Carbene Manganese (NHC-Mn)

Xiao-Bing Lan, Zongren Ye, Ming Huang, Jiahao Liu, Yan Liu and Zhuofeng Ke

Org. Lett., 2019, 21, 8065
DOI: 10.1021/acs.orglett.9b03030

Nickel-Catalyzed Selective Monoamination of 1,2-Diols: An Affordable Approach to Amino Alcohols

Soumya Sree Samal, Murugan Subaramanian and Ekambaram Balaraman

Org. Lett., 2025, 27, 9599
DOI: 10.1021/acs.orglett.5c02536

Hydrosilylation and Silane Polymerization Catalyzed by Group 4 Amidometallocene Cations

Tereza Edlová, Adrien T. Normand, Hélène Cattey, Stéphane Brandès, Yue Wu, Ariana Antonangelo, Benjamin Théron, Quentin Bonnin, Mariolino Carta and Pierre Le Gendre

Organometallics, 2023, 42, 1166
DOI: 10.1021/acs.organomet.2c00642

N‐alkylation of benzamides/sulfonamides using alcohols via borrowing hydrogen approach by well‐defined Pd (II) pincer complexes

Pennamuthiriyan Anandaraj and Rengan Ramesh

Applied Organom Chemis, 2023, 37
DOI: 10.1002/aoc.7228

Mechanistic study on the conversion of primary alcohols and butadiene into branched ketones using a rhodium catalyst

Chaiyaporn Lakmuang, Natcha Prommoon, Natnicha Namwong, Vudhichai Parasuk and Boodsarin Sawatlon

Molecular Catalysis, 2025, 583, 115237
DOI: 10.1016/j.mcat.2025.115237

Advances in Nonprecious Metal Homogeneously Catalyzed Formic Acid Dehydrogenation

Manuel Iglesias and Francisco J. Fernández-Alvarez

Catalysts, 2021, 11, 1288
DOI: 10.3390/catal11111288

C3-Alkylation of indoles and oxindoles by alcohols by means of borrowing hydrogen methodology

Francesca Bartoccini, Michele Retini and Giovanni Piersanti

Tetrahedron Letters, 2020, 61, 151875
DOI: 10.1016/j.tetlet.2020.151875

Borrowing Hydrogen-Mediated N-Alkylation Reactions by a Well-Defined Homogeneous Nickel Catalyst

Amreen K. Bains, Abhishek Kundu, Sudha Yadav and Debashis Adhikari

ACS Catal., 2019, 9, 9051
DOI: 10.1021/acscatal.9b02977

A Simple Iron-Catalyst for Alkenylation of Ketones Using Primary Alcohols

Motahar Sk, Ashish Kumar, Jagadish Das and Debasis Banerjee

Molecules, 2020, 25, 1590
DOI: 10.3390/molecules25071590

Simple RuCl3‐catalyzed N‐Methylation of Amines and Transfer Hydrogenation of Nitroarenes using Methanol

Naina Sarki, Vishakha Goyal, Nitin Kumar Tyagi, Puttaswamy, Anand Narani, Anjan Ray and Kishore Natte

ChemCatChem, 2021, 13, 1722
DOI: 10.1002/cctc.202001937

Sustainable Synthesis of α‐Hydroxycarboxylic Acids by Manganese Catalyzed Acceptorless Dehydrogenative Coupling of Ethylene Glycol and Primary Alcohols**

Satyadeep Waiba, Kakoli Maji, Mamata Maiti and Biplab Maji

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202218329

Pyrenedione-Catalyzed α-Olefination of Nitriles under Visible-Light Photoredox Conditions

Amreen K. Bains, Yadav Ankit and Debashis Adhikari

Org. Lett., 2021, 23, 2019
DOI: 10.1021/acs.orglett.1c00162

Ruthenium‐Catalyzed Synthesis of α‐Alkylated Ketones and Quinolines in an Aqueous Medium via a Hydrogen‐Borrowing Strategy Using Ketones and Alcohols

Ashutosh Verma, Susanta Hazra, Pritam Dolui and Anil J. Elias

Asian J Org Chem, 2021, 10, 626
DOI: 10.1002/ajoc.202000686

Advances in Cross-Coupling Reactions Catalyzed by Aromatic Pincer Complexes Based on Earth-Abundant 3d Metals (Mn, Fe, Co, Ni, Cu)

Jesús Antonio Cruz-Navarro, Arturo Sánchez-Mora, Juan S. Serrano-García, Andrés Amaya-Flórez, Raúl Colorado-Peralta, Viviana Reyes-Márquez and David Morales-Morales

Catalysts, 2024, 14, 69
DOI: 10.3390/catal14010069

Nickel-Catalyzed Direct Synthesis of Quinoxalines from 2-Nitroanilines and Vicinal Diols: Identifying Nature of the Active Catalyst

Sujan Shee, Dibyajyoti Panja and Sabuj Kundu

J. Org. Chem., 2020, 85, 2775
DOI: 10.1021/acs.joc.9b03104

Stereo‐ and Site‐Selective Crotylation of Alcohol Proelectrophiles via Ruthenium‐Catalyzed Hydrogen Auto‐Transfer Mediated by Methylallene and Butadiene

Eliezer Ortiz, Brian J. Spinello, Yoon Cho, Jessica Wu and Michael J. Krische

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202212814

Borrowing Hydrogen for Organic Synthesis

Benjamin G. Reed-Berendt, Daniel E. Latham, Mubarak B. Dambatta and Louis C. Morrill

ACS Cent. Sci., 2021, 7, 570
DOI: 10.1021/acscentsci.1c00125

Direct N‐Alkylation of Amines with Alcohols Catalyzed by N‐Heterocyclic Carbene Cobalt‐Pincer Catalyst under Mild Conditions

Xin Liu, Yilei Ge, Yang Yang, Minghe Zhang, Siqi Yang and Xiaobing Lan

Asian J Org Chem, 2024, 13
DOI: 10.1002/ajoc.202300551

Catalytic Enantioselective C–C Coupling of Alcohols for Polyketide Total Synthesis beyond Chiral Auxiliaries and Premetalated Reagents

Jessica Wu, Katherine L. Verboom and Michael J. Krische

Chem. Rev., 2024, 124, 13715
DOI: 10.1021/acs.chemrev.4c00858

Metal–Ligand Cooperativity via Π–Π Interactions Supporting Outer‐Sphere Hydride Transfer

Ashu Singh, Vishal Jaiswal, Shilpi Misra and Amrendra K. Singh

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202501301

Recent Developments in Borrowing Hydrogen Methodology in N-alkylation of Amines

Shruti Yadav, Deepti Pal and Sushil K. Maurya

Top Curr Chem (Z), 2025, 383
DOI: 10.1007/s41061-025-00523-x

Iron in Organometallic Transformations: A Sustainable Substitute for Noble Metals

Rohit Kumar, Tanuja Tewari and Samir H. Chikkali

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202400756

Development of a Mild and Efficient Process for Ir-Catalyzed N-Alkylation of 4-Bromopyridin-2-amine with a Primary Alcohol via Borrowing Hydrogen

Sri Krishna Nimmagadda, Srinivas Kalidindi, Siva Sankar Bondigela, Satish Korapati, Debottam Dasgupta, Noormohamed Abdul Malik, Prakasa Rao, Prantik Maity, John R. Coombs, Michael Hay, Eric M. Simmons, Sabuj Mukherjee, Rajappa Vaidyanathan, Martin D. Eastgate and Francisco González-Bobes

Org. Process Res. Dev., 2024, 28, 3414
DOI: 10.1021/acs.oprd.4c00269

Iron‐Catalyzed Borrowing Hydrogen C‐Alkylation of Oxindoles with Alcohols

Mubarak B. Dambatta, Kurt Polidano, Alexander D. Northey, Jonathan M. J. Williams and Louis C. Morrill

ChemSusChem, 2019, 12, 2345
DOI: 10.1002/cssc.201900799

Iron-Catalyzed β-Alkylation of Alcohols

Léo Bettoni, Sylvain Gaillard and Jean-Luc Renaud

Org. Lett., 2019, 21, 8404
DOI: 10.1021/acs.orglett.9b03171

Blue-Light-Induced Iron-Catalyzed α-Alkylation of Ketones

Marie-Samira Abdallah, Nicolas Joly, Sylvain Gaillard, Albert Poater and Jean-Luc Renaud

Org. Lett., 2022, 24, 5584
DOI: 10.1021/acs.orglett.2c02233

Manganese-Catalyzed N-Alkylation of Sulfonamides Using Alcohols

Benjamin G. Reed-Berendt and Louis C. Morrill

J. Org. Chem., 2019, 84, 3715
DOI: 10.1021/acs.joc.9b00203

Cobalt-catalyzed dehydrogenative functionalization of alcohols: Progress and future prospect

Ishani Borthakur, Anirban Sau and Sabuj Kundu

Coordination Chemistry Reviews, 2022, 451, 214257
DOI: 10.1016/j.ccr.2021.214257

Manganese-Catalyzed Reformation of Vicinal Glycols to α-Hydroxy Carboxylic Acids with the Liberation of Hydrogen Gas

Satyadeep Waiba, Mamata Maiti and Biplab Maji

ACS Catal., 2022, 12, 3995
DOI: 10.1021/acscatal.1c05844

Blue light promoted room temperature iron-catalyzed C3-alkylation of indenes by alcohols via borrowing hydrogen methodology

Subash Nethaji Narayanasamy, Lingfeng Zhao and Christophe Darcel

Journal of Catalysis, 2026, 456, 116764
DOI: 10.1016/j.jcat.2026.116764

Dynamic Kinetic Resolution Allows Control of Remote Stereochemistry in Asymmetric Hydrogen Borrowing Alkylation

Daniella M. J. Cheang, Jessica L. Crompton, Mostafa M. Amer, Francisco Battiti, Bastian Bjerkem Skjelstad, Kirsten E. Christensen, Peter Barton, Fernanda Duarte and Timothy J. Donohoe

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202424959

Ruthenium‐Catalyzed Butadiene‐Mediated Crotylation and Oxazaborolidine‐Catalyzed Vinylogous Mukaiyama Aldol Reaction for The Synthesis of C1–C19 and C23–C35 of Neaumycin B

Xinting Liang, Minjin Yoo, Tabitha Schempp, Saki Maejima and Michael J. Krische

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202214786

From Hydrogenation to Transfer Hydrogenation to Hydrogen Auto-Transfer in Enantioselective Metal-Catalyzed Carbonyl Reductive Coupling: Past, Present, and Future

Catherine Gazolla Santana and Michael J. Krische

ACS Catal., 2021, 11, 5572
DOI: 10.1021/acscatal.1c01109

Ruthenium‐Catalyzed Three‐Component Alkylation: A Tandem Approach to the Synthesis of Nonsymmetric N,N‐Dialkyl Acyl Hydrazides with Alcohols

Léo Bettoni, Nicolas Joly, Jean‐François Lohier, Sylvain Gaillard, Albert Poater and Jean‐Luc Renaud

Adv Synth Catal, 2021, 363, 4009
DOI: 10.1002/adsc.202100554

B(C6F5)3-Catalyzed Direct C3 Alkylation of Indoles and Oxindoles

Shyam Basak, Ana Alvarez-Montoya, Laura Winfrey, Rebecca L. Melen, Louis C. Morrill and Alexander P. Pulis

ACS Catal., 2020, 10, 4835
DOI: 10.1021/acscatal.0c01141

Ruthenium and Iron‐Catalysed Decarboxylative N‐alkylation of Cyclic α‐Amino Acids with Alcohols: Sustainable Routes to Pyrrolidine and Piperidine Derivatives

Anastasiia Afanasenko, Rachael Hannah, Tao Yan, Saravanakumar Elangovan and Katalin Barta

ChemSusChem, 2019, 12, 3801
DOI: 10.1002/cssc.201901499

Alcohol Dehydrogenation-Triggered Selective C3-Alkylation of Indoles by Homogeneous Azo-aromatic Cobalt Catalysts

Kamal, Manas Khatua, Swati Rani, Bappaditya Goswami and Subhas Samanta

J. Org. Chem., 2023, 88, 5827
DOI: 10.1021/acs.joc.3c00248

Manganese‐Catalyzed β‐Methylation of Alcohols by Methanol

Martin Schlagbauer, Fabian Kallmeier, Torsten Irrgang and Rhett Kempe

Angew Chem Int Ed, 2020, 59, 1485
DOI: 10.1002/anie.201912055

Synthesis of Enantioenriched Amines by Iron‐Catalysed Amination of Alcohols Employing at Least One Achiral Substrate

Giovanni Bottari, Anastasiia Afanasenko, Antonio A. Castillo‐Garcia, Ben L. Feringa and Katalin Barta

Adv Synth Catal, 2021, 363, 5436
DOI: 10.1002/adsc.202100231

Amination of β-hydroxyl acid esters via cooperative catalysis enables access to bio-based β-amino acid esters

Anastasiia Afanasenko, Tao Yan and Katalin Barta

Commun Chem, 2019, 2
DOI: 10.1038/s42004-019-0229-x

Homogeneous first-row transition metal catalyst for sustainable hydrogen production and organic transformation from methanol, formic acid, and bio-alcohols

Jagannath Rana, Satabdee Tanaya Sahoo and Prosenjit Daw

Tetrahedron, 2021, 99, 132473
DOI: 10.1016/j.tet.2021.132473

Functional group tolerant hydrogen borrowing C-alkylation

Elliot P. Bailey, Timothy J. Donohoe and Martin D. Smith

Nat Commun, 2024, 15
DOI: 10.1038/s41467-024-49249-2

Recent Advances in the Catalytic N-Methylation and N-Trideuteromethylation Reactions Using Methanol and Deuterated Methanol

Jagadeesh Rajenahally, Vishakha Vishakha, Naina Sarki, Anand Narani, Ganesh Naik and Kishore Natte

SSRN Journal, 2022
DOI: 10.2139/ssrn.4102605

Synthesis of Indanones and Spiroindanones by Diastereoselective Annulation Based on a Hydrogen Autotransfer Strategy

Yate Chen, Zhengtian Ding, Yiming Wang, Wenfeng Liu and Wangqing Kong

Angew Chem Int Ed, 2021, 60, 5273
DOI: 10.1002/anie.202013792

Air-Stable Efficient Nickel Catalyst for Hydrogenation of Organic Compounds

Vladyslav V. Subotin, Mykyta O. Ivanytsya, Anastasiya V. Terebilenko, Pavel S. Yaremov, Olena O. Pariiska, Yuri M. Akimov, Igor E. Kotenko, Tomash M. Sabov, Mykhailo M. Kurmach, Sergey V. Ryabukhin, Dmitriy M. Volochnyuk and Sergey V. Kolotilov

Catalysts, 2023, 13, 706
DOI: 10.3390/catal13040706

Iron- and Organo-Catalyzed Borrowing Hydrogen for the Stereoselective Construction of Tetrahydropyrans

Anestis Alexandridis, Thibault Rancon, Abigail Halliday, Amélie Kochem and Adrien Quintard

Org. Lett., 2024, 26, 5788
DOI: 10.1021/acs.orglett.4c01969

Synthesis of 2H-pyrroles via iron catalyzed dehydrogenative coupling and C–C bond cleavage

Suya Cui, Xiaoyun Wu, Wei Ma, Weijun Tang, Huaming Sun, Jianliang Xiao, Dong Xue and Chao Wang

Green Synthesis and Catalysis, 2021, 2, 307
DOI: 10.1016/j.gresc.2021.04.007

Manganese-catalyzed C–C and C–N bond formation with alcohols via borrowing hydrogen or hydrogen auto-transfer

Mohd Farhan Ansari, Atul Kumar Maurya, Abhishek Kumar and Saravanakumar Elangovan

Beilstein J. Org. Chem., 2024, 20, 1111
DOI: 10.3762/bjoc.20.98

Modulating Catalytic Selectivity by Base Addition in Aqueous Reductive Amination of 1,6-Hexanediol Using Ru/C

Navneet Kumar Gupta, Phillip Palenicek, Lucas Nortmeyer, Gregor Maurice Meyer, Timo Schäfer, Tim Hellmann, Jan P. Hofmann and Marcus Rose

ACS Sustainable Chem. Eng., 2022, 10, 14560
DOI: 10.1021/acssuschemeng.2c04301

Stereo‐ and Site‐Selective Crotylation of Alcohol Proelectrophiles via Ruthenium‐Catalyzed Hydrogen Auto‐Transfer Mediated by Methylallene and Butadiene

Eliezer Ortiz, Brian J. Spinello, Yoon Cho, Jessica Wu and Michael J. Krische

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202212814

Iron-Catalyzed Ligand Free α-Alkylation of Methylene Ketones and β-Alkylation of Secondary Alcohols Using Primary Alcohols

Anitha Alanthadka, Sourajit Bera and Debasis Banerjee

J. Org. Chem., 2019, 84, 11676
DOI: 10.1021/acs.joc.9b01600

Control of Absolute Stereochemistry in Transition‐Metal‐Catalysed Hydrogen‐Borrowing Reactions

Timothy Kwok, Oskar Hoff, Roly J. Armstrong and Timothy J. Donohoe

Chemistry A European J, 2020, 26, 12912
DOI: 10.1002/chem.202001253

Bio‐Based Surfactants via Borrowing Hydrogen Catalysis

Maximilian Koy, Maximilian Fellert, Chuting Deng, Michiel T. Uiterweerd, Alicia Lessentier, Minyan Wu, Mickael Cregut, Jianxia Zheng, Stephane Streiff, Juan J. de Pablo and Ben L. Feringa

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202500077

A Vinyl Cyclopropane Ring Expansion and Iridium‐Catalyzed Hydrogen Borrowing Cascade

Simon Wübbolt, Choon Boon Cheong, James R. Frost, Kirsten E. Christensen and Timothy J. Donohoe

Angewandte Chemie, 2020, 132, 11435
DOI: 10.1002/ange.202003614

Carbon Dioxide Hydrogenation to Formate Catalyzed by a Bench-Stable, Non-Pincer-Type Mn(I) Alkylcarbonyl Complex

Sylwia Kostera, Stefan Weber, Maurizio Peruzzini, Luis F. Veiros, Karl Kirchner and Luca Gonsalvi

Organometallics, 2021, 40, 1213
DOI: 10.1021/acs.organomet.0c00710

Mössbauer Spectroscopic and Computational Investigation of An Iron Cyclopentadienone Complex

Ikram Yagoub, Martin Clémancey, Pierre-Alain Bayle, Adrien Quintard, Guillaume Delattre, Geneviève Blondin and Amélie Kochem

Inorg. Chem., 2021, 60, 11192
DOI: 10.1021/acs.inorgchem.1c01155

Influence of the Structure of Nanocomposites Based on Co,N,S-Doped Carbon and Co9S8 on the Catalytic Properties in the Processes of Quinoline and Its Methyl Derivatives Hydrogenation

O. O. Pariiska, D. O. Mazur, V. M. Asaula, V. V. Buryanov, R. Socha, Ya.I. Kurys, S. V. Kolotilov, V. G. Koshechko and V. D. Pokhodenko

Theor Exp Chem, 2023, 58, 417
DOI: 10.1007/s11237-023-09757-6

Ruthenium‐Catalyzed Butadiene‐Mediated Crotylation and Oxazaborolidine‐Catalyzed Vinylogous Mukaiyama Aldol Reaction for The Synthesis of C1–C19 and C23–C35 of Neaumycin B

Xinting Liang, Minjin Yoo, Tabitha Schempp, Saki Maejima and Michael J. Krische

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202214786

α‐Alkylation of Ketones with Secondary Alcohols Catalyzed by Well‐Defined Cp*CoIII‐Complexes

Priyanka Chakraborty, Manoj Kumar Gangwar, Balakumar Emayavaramban, Eric Manoury, Rinaldo Poli and Basker Sundararaju

ChemSusChem, 2019, 12, 3463
DOI: 10.1002/cssc.201900990

Hydrogen‐Borrowing‐Based Methods for the Construction of Quaternary Stereocentres

Jessica L. Crompton, Timothy C. Jenkins, Sam M. Rowe and Timothy J. Donohoe

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202423179

Synthesis of 1,8-Dioxo-decahydroacridine Derivatives via Ru-Catalyzed Acceptorless Dehydrogenative Multicomponent Reaction

Nandita Biswas and Dipankar Srimani

J. Org. Chem., 2021, 86, 9733
DOI: 10.1021/acs.joc.1c01075

Asymmetric Guerbet Reaction to Access Chiral Alcohols

Kun Wang, Lin Zhang, Weijun Tang, Huaming Sun, Dong Xue, Ming Lei, Jianliang Xiao and Chao Wang

Angewandte Chemie, 2020, 132, 11505
DOI: 10.1002/ange.202003104

Implementation of Cooperative Designs in Polarized Transition Metal Systems—Significance for Bond Activation and Catalysis

Basujit Chatterjee, Wei-Chieh Chang, Soumyashree Jena and Christophe Werlé

ACS Catal., 2020, 10, 14024
DOI: 10.1021/acscatal.0c03794

Enantioselective N-Heteroaryl C–H Functionalization for Piperidine-Azine Conjugation: Alkynes as Allylmetal Pronucleophiles in Dearomative Addition-Hydrogen Auto-Transfer

Seoyoung Lee, Yhin Sarah Teoh, Pei-Pei Xie, Erin M. McManus, Brandon I. Gonzalez, Tate A. Claggett, Peng Liu and Michael J. Krische

J. Am. Chem. Soc., 2025, 147, 41946
DOI: 10.1021/jacs.5c15097

Cooperative Bimetallic Co−Mn Catalyst: Exploiting Metallo‐Organic and Hydrogen Bonded Interactions for Rechargeable C‐/N‐Alkylation

Manohar Shivaji Padmor, Palak Vishwakarma, Srinu Tothadi and Sanjay Pratihar

ChemCatChem, 2023, 15
DOI: 10.1002/cctc.202300828

Phosphine-Free Ruthenium Complex-Catalyzed Synthesis of Mono- or Dialkylated Acyl Hydrazides via the Borrowing Hydrogen Strategy

Nicolas Joly, Léo Bettoni, Sylvain Gaillard, Albert Poater and Jean-Luc Renaud

J. Org. Chem., 2021, 86, 6813
DOI: 10.1021/acs.joc.1c00654

Iron-Catalyzed Tandem Three-Component Alkylation: Access to α-Methylated Substituted Ketones

Léo Bettoni, Charlotte Seck, Mbaye Diagne Mbaye, Sylvain Gaillard and Jean-Luc Renaud

Org. Lett., 2019, 21, 3057
DOI: 10.1021/acs.orglett.9b00630

Cobalt Catalyzed N‐Methylation of Amides using Methanol

Bhaskar Paul, Milan Maji, Dibyajyoti Panja and Sabuj Kundu

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202100678

Molybdenum‐Catalyzed Asymmetric Amination of α‐Hydroxy Esters: Synthesis of α‐Amino Acids

Shahida Perveen, Tahir Rahman, Tariq Ali, Lingyun Wang, Junjie Zhang and Ajmal Khan

Advanced Science, 2025, 12
DOI: 10.1002/advs.202403437

Iridium-Catalyzed Alkylation of Secondary Alcohols with Primary Alcohols: A Route to Access Branched Ketones and Alcohols

Sertaç Genç, Süleyman Gülcemal, Salih Günnaz, Bekir Çetinkaya and Derya Gülcemal

J. Org. Chem., 2020, 85, 9139
DOI: 10.1021/acs.joc.0c01099

Trapping Hydrogen: Confined Catalysis for Improved Alcohol Amination Selectivity

Julio C. S. Terra, Jackson DeWolfe, Jesus A. Valdez and Audrey Moores

ChemCatChem, 2025, 17
DOI: 10.1002/cctc.202401941

Acridine-Based SNS–Ruthenium Pincer Complex-Catalyzed Borrowing Hydrogen-Mediated C–C Alkylation Reaction: Application to the Guerbet Reaction

Nandita Biswas, Rahul Sharma, Bitan Sardar and Dipankar Srimani

Synlett, 2023, 34, 622
DOI: 10.1055/a-1874-2406

Synchronous Proton‐Hydride Transfer by a Pyrazole‐Functionalized Protic Mn(I) Complex in Catalytic Alcohol Dehydrogenative Coupling

Subhabrata De, Prabodh Ranjan, Vishal Chaurasia, Sourav Pal, Saikat Pal, Pragati Pandey and Jitendra K. Bera

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202301758

Intermolekulare stereospezifische Substitution von underivatisierten enantiomerenangereicherten sekundären Alkoholen durch Organokatalyse

Sunisa Akkarasamiyo and Joseph S. M. Samec

Angewandte Chemie, 2019, 131, 18074
DOI: 10.1002/ange.201911532

A Vinyl Cyclopropane Ring Expansion and Iridium‐Catalyzed Hydrogen Borrowing Cascade

Simon Wübbolt, Choon Boon Cheong, James R. Frost, Kirsten E. Christensen and Timothy J. Donohoe

Angew Chem Int Ed, 2020, 59, 11339
DOI: 10.1002/anie.202003614

Tungsten‐Catalyzed Direct N‐Alkylation of Anilines with Alcohols

Xiao‐Bing Lan, Zongren Ye, Chenhui Yang, Weikang Li, Jiahao Liu, Ming Huang, Yan Liu and Zhuofeng Ke

ChemSusChem, 2021, 14, 860
DOI: 10.1002/cssc.202002830

TBN‐Catalyzed Dehydrative N‐Alkylation of Anilines with 4‐Hydroxybutan‐2‐one

Wenchen Cheng, Shue Deng, Liya Jiang, Lanhui Ren, Zicheng Wang, Jian Zhang and Weiguo Song

Eur J Org Chem, 2019, 2019, 7372
DOI: 10.1002/ejoc.201901472

Access to Saturated Aza‐Heterocycles using the Borrowing Hydrogen Methodology

Maïwenn Jacolot and Florence Popowycz

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202301119

Enantioselective Borrowing Hydrogen: A Modern Tool to Construct Enantioenriched Molecules

Anestis Alexandridis and Adrien Quintard

ChemCatChem, 2024, 16
DOI: 10.1002/cctc.202400902

Cyclometalated Iridium Complex-Catalyzed N-Alkylation of Amines with Alcohols via Borrowing Hydrogen in Aqueous Media

NianHua Luo, YuHong Zhong, HuiLing Wen and Renshi Luo

ACS Omega, 2020, 5, 27723
DOI: 10.1021/acsomega.0c04192

Nickel Complexes of 4,5-Bis(diorganophosphinomethyl)acridine Ligands

Maximilian Roca Jungfer, Frank Rominger, Thomas Oeser, A. Stephen K. Hashmi and Thomas Schaub

Organometallics, 2025, 44, 882
DOI: 10.1021/acs.organomet.5c00033

Lewis Base Catalysis Promoted Nucleophilic Substitutions – Recent Advances and Future Directions

Peter H. Huy

Eur J Org Chem, 2020, 2020, 10
DOI: 10.1002/ejoc.201901495

Catalytic Production of Aromatic Amines from Nitroaromatics—Addressing a Critical Challenge in Environmental Remediation

Patrick Niyirora and Piotr Cyganowski

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202500281

Nickel‐Catalysis Enabling α‐Alkylation of Ketones by Secondary Alcohols

Amreen K Bains, Ayanangshu Biswas, Abhishek Kundu and Debashis Adhikari

Adv Synth Catal, 2022, 364, 2815
DOI: 10.1002/adsc.202200522

Vanadium- and Chromium-Catalyzed Dehydrogenative Synthesis of Imines from Alcohols and Amines

Yulong Miao, Simone V. Samuelsen and Robert Madsen

Organometallics, 2021, 40, 1328
DOI: 10.1021/acs.organomet.1c00123

Synthesis of Indanones and Spiroindanones by Diastereoselective Annulation Based on a Hydrogen Autotransfer Strategy

Yate Chen, Zhengtian Ding, Yiming Wang, Wenfeng Liu and Wangqing Kong

Angewandte Chemie, 2021, 133, 5333
DOI: 10.1002/ange.202013792

Highly active primary amine ligated Ru(II)-arene complexes as selective catalysts for solvent-free N-alkylation of Anilines

Bhaskarjyoti Sarma, Rishi Ranjan, Nimesh R. Chauhan, Suman Mukhopadhyay, Angshuman Roy Choudhury and Komal M. Vyas

Molecular Catalysis, 2023, 548, 113440
DOI: 10.1016/j.mcat.2023.113440

Transition-metal-catalyzed domino reactions of strained bicyclic alkenes

Austin Pounder, Eric Neufeld, Peter Myler and William Tam

Beilstein J. Org. Chem., 2023, 19, 487
DOI: 10.3762/bjoc.19.38

Chromium‐Catalyzed Alkylation of Amines by Alcohols

Fabian Kallmeier, Robin Fertig, Torsten Irrgang and Rhett Kempe

Angewandte Chemie, 2020, 132, 11887
DOI: 10.1002/ange.202001704

Mechanistic Studies of Hydride Transfer to Imines from a Highly Active and Chemoselective Manganate Catalyst

Frederik Freitag, Torsten Irrgang and Rhett Kempe

J. Am. Chem. Soc., 2019, 141, 11677
DOI: 10.1021/jacs.9b05024

Copper-Catalyzed α-Alkylation of Aryl Acetonitriles with Benzyl Alcohols

Marianna Danopoulou, Leandros P. Zorba, Athanasia P. Karantoni, Demeter Tzeli and Georgios C. Vougioukalakis

J. Org. Chem., 2024, 89, 14242
DOI: 10.1021/acs.joc.4c01662

Zinc‐Catalyzed N‐Alkylation of Aromatic Amines with Alcohols: A Ligand‐Free Approach

Velayudham Sankar, Murugavel Kathiresan, Bitragunta Sivakumar and Subramaniyan Mannathan

Adv Synth Catal, 2020, 362, 4409
DOI: 10.1002/adsc.202000499

Late stage modifications of phosphine oxide ligands by iron‐catalyzed hydrogen borrowing reactions

Jiajun Wu, Subash Nethaji Narayanasamy and Christophe Darcel

Journal of Organometallic Chemistry, 2022, 979, 122510
DOI: 10.1016/j.jorganchem.2022.122510

Borrowing Hydrogen Amination Reactions: A Complex Analysis of Trends and Correlations of the Various Reaction Parameters

Evgeniya Podyacheva, Oleg I. Afanasyev, Dmitry V. Vasilyev and Denis Chusov

ACS Catal., 2022, 12, 7142
DOI: 10.1021/acscatal.2c01133

Pentamethylphenyl (Ph*) ketones: Unique building blocks for organic synthesis

Roly J. Armstrong and Timothy J. Donohoe

Tetrahedron Letters, 2021, 74, 153151
DOI: 10.1016/j.tetlet.2021.153151

Leveraging the Stereochemical Complexity of Octahedral Diastereomeric-at-Metal Catalysts to Unlock Regio-, Diastereo-, and Enantioselectivity in Alcohol-Mediated C–C Couplings via Hydrogen Transfer

Jonathan Z. Shezaf, Catherine G. Santana, Eliezer Ortiz, Cole C. Meyer, Peng Liu, Ken Sakata, Kuo-Wei Huang and Michael J. Krische

J. Am. Chem. Soc., 2024, 146, 7905
DOI: 10.1021/jacs.4c01857

Ruthenium Complexes with NNN-Pincer Ligands for N-Methylation of Amines Using Methanol

Mengxuan Bai, Shengxin Zhang, Zhengguo Lin, Zhiqiang Hao, Zhangang Han, Guo-Liang Lu and Jin Lin

Inorg. Chem., 2024, 63, 11821
DOI: 10.1021/acs.inorgchem.4c01561

Blue‐Light Induced Iron‐Catalyzed Synthesis of γ,δ‐Unsaturated Ketones

Nicolas Joly, Alessandro Colella, Monique‐Edwige Mendy, Mbaye Diagne Mbaye, Sylvain Gaillard, Albert Poater and Jean‐Luc Renaud

ChemSusChem, 2024, 17
DOI: 10.1002/cssc.202301472

Selective Construction of C−C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides

Xin Liu and Thomas Werner

Adv Synth Catal, 2021, 363, 1096
DOI: 10.1002/adsc.202001209

Formal Synthesis of Fostriecin via Asymmetric Alcohol-Mediated Carbonyl Allylation

Dana E. Pfaffinger and Michael J. Krische

Org. Lett., 2025, 27, 4501
DOI: 10.1021/acs.orglett.5c01026

Ionic‐Liquid Hydrogen‐Bonding Promoted Alcohols Amination over Cobalt Catalyst via Dihydrogen Autotransfer Mechanism

Zhengang Ke, Yuepeng Wang, Yanfei Zhao, Minhao Tang, Wei Zeng, Ying Wang, Xiaoqian Chang, Buxing Han and Zhimin Liu

ChemSusChem, 2023, 16
DOI: 10.1002/cssc.202300513

Design, facile synthesis, spectroscopic characterization, and medicinal probing of metal‐based new sulfonamide drugs: A theoretical and spectral study

Abrar U. Hassan, Sajjad H. Sumrra, Muhammad A. Raza, Muhammad Zubair, Muhammad N. Zafar, Ehsan U. Mughal, Muhammad F. Nazar, Ahmad Irfan, Muhammad Imran and Mohammed A. Assiri

Applied Organom Chemis, 2021, 35
DOI: 10.1002/aoc.6054

Direct access to 2-(N-alkylamino)pyrimidines via ruthenium catalyzed tandem multicomponent annulation/N-alkylation

Milan Maji, Ishani Borthakur, Saikat Guria, Suman Singha and Sabuj Kundu

Journal of Catalysis, 2021, 402, 37
DOI: 10.1016/j.jcat.2021.08.010

Sustainable Synthesis of α‐Hydroxycarboxylic Acids by Manganese Catalyzed Acceptorless Dehydrogenative Coupling of Ethylene Glycol and Primary Alcohols**

Satyadeep Waiba, Kakoli Maji, Mamata Maiti and Biplab Maji

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202218329

Analysis of thermodynamics, kinetics, and reaction pathways in the amination of secondary alcohols over Ru/SiO2

Xin Gao, Dia Sahsah, Andreas Heyden and Jesse Q. Bond

Journal of Catalysis, 2023, 424, 74
DOI: 10.1016/j.jcat.2023.05.003

Ruthenium-catalyzed C–H bond functionalization in cascade and one-pot transformations

Rafael Gramage-Doria and Christian Bruneau

Coordination Chemistry Reviews, 2021, 428, 213602
DOI: 10.1016/j.ccr.2020.213602

Chemo- and Regioselective Synthesis of Acyl-Cyclohexenes by a Tandem Acceptorless Dehydrogenation-[1,5]-Hydride Shift Cascade

Lewis B. Smith, Roly J. Armstrong, Daniel Matheau-Raven and Timothy J. Donohoe

J. Am. Chem. Soc., 2020, 142, 2514
DOI: 10.1021/jacs.9b12296

Application of NHC‐Based Iridium Pincer Complexes in β‐Alkylation of Alcohols and N‐Alkylation of Amines: Mechanistic Studies on Precatalyst Activation

Miguel González‐Lainez, M. Victoria Jiménez, F. Javier Modrego and Jesús J. Pérez‐Torrente

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.202401665

One-Pot Conversion of Allylic Alcohols to α-Methyl Ketones via Iron-Catalyzed Isomerization–Methylation

Daniel E. Latham, Kurt Polidano, Jonathan M. J. Williams and Louis C. Morrill

Org. Lett., 2019, 21, 7914
DOI: 10.1021/acs.orglett.9b02900

Enantioconvergent Hydrobenzylation of Racemic Allylic Alcohols with Aryl Hydrazones via Bifunctional Ruthenium Catalysis

Jian Zhang, Ka Key Cheung, Mingyang Song, Weijun Tang, Huaming Sun, Zhenyang Lin, Jianliang Xiao and Chao Wang

J. Am. Chem. Soc., 2025, 147, 27790
DOI: 10.1021/jacs.5c06622

Asymmetric Ruthenium-Catalyzed Carbonyl Allylations by Gaseous Allene via Hydrogen Auto-Transfer: 1° versus 2° Alcohol Dehydrogenation for Streamlined Polyketide Construction

Connor Saludares, Eliezer Ortiz, Cate G. Santana, Brian J. Spinello and Michael J. Krische

ACS Catal., 2023, 13, 1662
DOI: 10.1021/acscatal.2c05425

Isomerization of cis-2,5-Di(hydroxymethyl)tetrahydrofuran to its trans-Isomer and the Effect of the cis/trans Ratio on the Properties of its Polyester with 1,12-Dodecanedioic Acid

Brian Spiegelberg, Claas Schünemann, Alexander Kux, Adrian Brandt, Andreas Taden, Horst Beck, Christian Hering-Junghans, Sergey Tin and Johannes G. de Vries

ACS Sustainable Chem. Eng., 2025, 13, 9195
DOI: 10.1021/acssuschemeng.5c02541

Nickel Pincer Complexes Catalyzed Sustainable Synthesis of 3,4-Dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxides via Acceptorless Dehydrogenative Coupling of Primary Alcohols

Anandaraj Pennamuthiriyan and Ramesh Rengan

J. Org. Chem., 2024, 89, 2494
DOI: 10.1021/acs.joc.3c02508

Manganese Catalyzed Acceptorless Dehydrogenative Coupling Reactions

Satyadeep Waiba and Biplab Maji

ChemCatChem, 2020, 12, 1891
DOI: 10.1002/cctc.201902180

Self‐Suspended Nanoparticles for N‐Alkylation Reactions: A New Concept for Catalysis

Maria Sarno, Claudia Cirillo and Mariagrazia Iuliano

ChemistryOpen, 2019, 8, 520
DOI: 10.1002/open.201900104

Dimethylamination of Primary Alcohols Using a Homogeneous Iridium Catalyst: A Synthetic Method for N,N-Dimethylamine Derivatives

Jaeyoung Jeong and Ken-ichi Fujita

J. Org. Chem., 2021, 86, 4053
DOI: 10.1021/acs.joc.0c02896

Selective N-alkylation of amines with alcohols via hydrogen transfer catalyzed by copper complex in an ionic liquid media

N. Asharani, S. Shakeel Nawaz, S. Ranganatha, S. Supriya and Dileep Ramakrishna

Chemical Engineering Journal Advances, 2024, 17, 100585
DOI: 10.1016/j.ceja.2024.100585

Organometallic Ru(III) Catalysts for α‐Alkylation of Carbonyl Compounds using Alcohols: Mechanistic Insights via Detection of Key Intermediates

Sain Singh, Rajat Saini, Virendra Kumar Chaudhary and Kaushik Ghosh

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.202400811

3d transition metal complexes as homogeneous catalysts in N-alkylation reactions using alcohols: A recent update

Jharna Mahato, Rima Das and Tanmoy Kumar Saha

Tetrahedron, 2024, 165, 134192
DOI: 10.1016/j.tet.2024.134192

Titanium-Catalyzed Cyano-Borrowing Reaction for the Direct Amination of Cyanohydrins with Ammonia

Qing-Hua Li, Zhao-Feng Li, Jing Tao, Wan-Fang Li, Li-Qing Ren, Qian Li, Yun-Gui Peng and Tang-Lin Liu

Org. Lett., 2019, 21, 8429
DOI: 10.1021/acs.orglett.9b03194

Co(II), Ni(II), Cu(II) and Zn(II) complexes of 1,8-naphthalimide-based ligand: syntheses, characterizations and evaluation of antibacterial activities

Sabiha A. Shaikh, Satish S. Bhat, Vidyanand K. Revankar, Naveen S., Mahesha, N.K. Loknath and Vijay Kumbar

Journal of Coordination Chemistry, 2023, 76, 1586
DOI: 10.1080/00958972.2023.2265037

Room-Temperature Metal-Catalyzed Hydrogen Borrowing Alkylation

Elliot P. Bailey, Timothy J. Donohoe and Martin D. Smith

ACS Catal., 2026, 16, 1858
DOI: 10.1021/acscatal.5c07305

Integrated Electro‐Biocatalysis for Amine Alkylation with Alcohols

Itziar Peñafiel, Robert A. W. Dryfe, Nicholas J. Turner and Michael F. Greaney

ChemCatChem, 2021, 13, 864
DOI: 10.1002/cctc.202001757

Metal-free, Oxidative α-Coupling of Aldehydes with Amine Nucleophiles for the Preparation of Congested C(sp3)–N Bonds

Nomaan M. Rezayee, Matilde Rusbjerg, Maximilian Marx, Sif T. Linde and Karl Anker Jørgensen

J. Org. Chem., 2022, 87, 1756
DOI: 10.1021/acs.joc.1c01937

Well‐Defined Ni−SNS Complex Catalysed Borrowing Hydrogenative α‐Alkylation of Ketones and Dehydrogenative Synthesis of Quinolines

Rahul Sharma, Avijit Mondal, Arup Samanta, Nandita Biswas, Babulal Das and Dipankar Srimani

Adv Synth Catal, 2022, 364, 2429
DOI: 10.1002/adsc.202200209

[(PPh3)2NiCl2]-Catalyzed C–N Bond Formation Reaction via Borrowing Hydrogen Strategy: Access to Diverse Secondary Amines and Quinolines

S. N. R. Donthireddy, Vipin K. Pandey and Arnab Rit

J. Org. Chem., 2021, 86, 6994
DOI: 10.1021/acs.joc.1c00510

Selective Labeling of Peptides with o‐Carboranes via Manganese(I)‐Catalyzed C−H Activation

Becky Bongsuiru Jei, Long Yang and Lutz Ackermann

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202200811

Hydricity of 3d Transition Metal Complexes from Density Functional Theory: A Benchmarking Study

Alister S. Goodfellow and Michael Bühl

Molecules, 2021, 26, 4072
DOI: 10.3390/molecules26134072

Oxidative Coupling of Alcohols and Amines Using Functionalized Cu(II) 2-Quinoxolinol Salen Catalysts

Xiaoyu Huo, Raymond Hicks, Ansh Chugh, Biswash Guragain, John D. Gorden and Anne E. V. Gorden

ACS Omega, 2026, 11, 10022
DOI: 10.1021/acsomega.5c10891

Heteroditopic NHC Ligand Supported Manganese(I) Complexes: Synthesis, Characterization, and Activity as Non‐bifunctional Phosphine‐Free Catalyst for the α‐Alkylation of Nitriles

Siva Nagendra Reddy Donthireddy and Arnab Rit

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202302504

Triflic Acid‐Catalyzed Dehydrative Amination of 2‐Arylethanols with Weak N‐Nucleophiles in Hexafluoroisopropanol

Max Van Hoof, Robert J. Mayer, Joseph Moran and David Lebœuf

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202417089

Manganese‐Catalyzed β‐Methylation of Alcohols by Methanol

Martin Schlagbauer, Fabian Kallmeier, Torsten Irrgang and Rhett Kempe

Angewandte Chemie, 2020, 132, 1501
DOI: 10.1002/ange.201912055

Well‐defined N‐heterocyclic carbene/ruthenium complexes for the alcohol amidation with amines: The dual role of cesium carbonate and improved activities applying an added ligand

Wan‐Qiang Wang, Ye Yuan, Yang Miao, Bao‐Yi Yu, Hua‐Jing Wang, Zhi‐Qin Wang, Wei Sang, Cheng Chen and Francis Verpoort

Applied Organom Chemis, 2020, 34
DOI: 10.1002/aoc.5323

3d-Metal Catalyzed N- and C-Alkylation Reactions via Borrowing Hydrogen or Hydrogen Autotransfer

Torsten Irrgang and Rhett Kempe

Chem. Rev., 2019, 119, 2524
DOI: 10.1021/acs.chemrev.8b00306

Unification of Ru and carbon support in catalytic aqueous 1,6-hexanediol amination

Phillip Palenicek, Hafila S. Khairun, Navneet Kumar Gupta, Sandeep Yadav, Aby Cheruvathoor Poulose, Aristides Bakandritsos, Jörg J. Schneider and Marcus Rose

Molecular Catalysis, 2025, 578, 115030
DOI: 10.1016/j.mcat.2025.115030

Direct Synthesis of Pyrrolo[1,2-α]quinoxalines via Iron-Catalyzed Transfer Hydrogenation between 1-(2-Nitrophenyl)pyrroles and Alcohols

Simin Chun, Jiwon Ahn, Ramachandra Reddy Putta, Seok Beom Lee, Dong-Chan Oh and Suckchang Hong

J. Org. Chem., 2020, 85, 15314
DOI: 10.1021/acs.joc.0c02145

Conversion of Primary Alcohols and Butadiene to Branched Ketones via Merged Transfer Hydrogenative Carbonyl Addition–Redox Isomerization Catalyzed by Rhodium

Brian J. Spinello, Jessica Wu, Yoon Cho and Michael J. Krische

J. Am. Chem. Soc., 2021, 143, 13507
DOI: 10.1021/jacs.1c07230

Ruthenium Pincer Complex Catalyzed Selective Synthesis of C‐3 Alkylated Indoles and Bisindolylmethanes Directly from Indoles and Alcohols

Nandita Biswas, Rahul Sharma and Dipankar Srimani

Adv Synth Catal, 2020, 362, 2902
DOI: 10.1002/adsc.202000326

Nickel‐Catalyzed Sequential Synthesis of Alkylated Quinolines and Their Photophysical Studies

Pari Keerthana and Fazlur Rahman Nawaz Khan

Asian J Org Chem, 2024, 13
DOI: 10.1002/ajoc.202400192

Understanding Halide Counterion Effects in Enantioselective Ruthenium-Catalyzed Carbonyl (α-Aryl)allylation: Alkynes as Latent Allenes and Trifluoroethanol-Enhanced Turnover in The Conversion of Ethanol to Higher Alcohols via Hydrogen Auto-transfer

Eliezer Ortiz, Jonathan Z. Shezaf, Yu-Hsiang Chang, Théo P. Gonçalves, Kuo-Wei Huang and Michael J. Krische

J. Am. Chem. Soc., 2021, 143, 16709
DOI: 10.1021/jacs.1c07857

N‐Alkylation of α‐Amino Esters and Amides through Hydrogen Borrowing

Charlotte E. Coomber and Louis J. Diorazio

Eur J Org Chem, 2022, 2022
DOI: 10.1002/ejoc.202200152

Nickel and Palladium Complexes with Reactive σ‐Metal‐Oxygen Covalent Bonds

Luis M. Martínez‐Prieto and Juan Cámpora

Israel Journal of Chemistry, 2020, 60, 373
DOI: 10.1002/ijch.202000001

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids

Christopher J. J. Hall, William R. F. Goundry and Timothy J. Donohoe

Angew Chem Int Ed, 2021, 60, 6981
DOI: 10.1002/anie.202100922

Switching the N‐Alkylation of Arylamines with Benzyl Alcohols to Imine Formation Enables the One‐Pot Synthesis of Enantioenriched α‐N‐Alkylaminophosphonates

Natalie Hofmann and Kai C. Hultzsch

Eur J Org Chem, 2019, 2019, 3105
DOI: 10.1002/ejoc.201900209

A Highly Active PN3 Manganese Pincer Complex Performing N-Alkylation of Amines under Mild Conditions

Leonard Homberg, Alexander Roller and Kai C. Hultzsch

Org. Lett., 2019, 21, 3142
DOI: 10.1021/acs.orglett.9b00832

New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines

Aaron Trowbridge, Scarlett M. Walton and Matthew J. Gaunt

Chem. Rev., 2020, 120, 2613
DOI: 10.1021/acs.chemrev.9b00462

A Palladium Complex Dispersed in Ionic Liquid as an Efficient Catalytic Combination for the Synthesis of Benzazoles

Dileep Ramakrishna, Supriya Saravu and Shashanka Rajendrachari

Top Catal, 2025, 68, 1232
DOI: 10.1007/s11244-021-01554-6

Visible light‐induced catalytic hydrosilylation of ketones mediated by manganese NHC complexes

Henrique Mourão, Clara S. B. Gomes, Sara Realista and Beatriz Royo

Applied Organom Chemis, 2024, 38
DOI: 10.1002/aoc.6846

Mechanistic Elucidation of an Alcohol Oxidation Reaction Promoted by a Nickel Azophenolate Complex

Rahul Singh, Amreen K. Bains, Abhishek Kundu, Harshit Jain, Sudha Yadav, Dhananjay Dey and Debashis Adhikari

Organometallics, 2023, 42, 1759
DOI: 10.1021/acs.organomet.2c00667

Iron-Catalyzed α-Alkylation of Ketones with Secondary Alcohols: Access to β-Disubstituted Carbonyl Compounds

Léo Bettoni, Sylvain Gaillard and Jean-Luc Renaud

Org. Lett., 2020, 22, 2064
DOI: 10.1021/acs.orglett.0c00549

Transition metal free α-C-alkylation of ketones using secondary alcohols

Mubarak B. Dambatta, Joseph Santos, Robert R.A. Bolt and Louis C. Morrill

Tetrahedron, 2020, 76, 131571
DOI: 10.1016/j.tet.2020.131571

Learning Green Chemistry Principles by Comparing Three Synthetic Routes to a Copper-NHC (NHC = N-heterocyclic carbene) Complex

Francis Bru, Sofie M. P. Vanden Broeck, Gianmarco Pisanò, Klaartje De Buysser and Catherine S. J. Cazin

J. Chem. Educ., 2023, 100, 2359
DOI: 10.1021/acs.jchemed.2c01134

Stereoselective synthesis of alicyclic ketones: A hydrogen borrowing approach

Roly J. Armstrong, Wasim M. Akhtar, James R. Frost, Kirsten E. Christensen, Neil G. Stevenson and Timothy J. Donohoe

Tetrahedron, 2019, 75, 130680
DOI: 10.1016/j.tet.2019.130680

Iron-catalyzed reductive cyclization of nitroarenes: Synthesis of aza-heterocycles and DFT calculations

Christine Tran, Aïcha Abdallah, Valentin Duchemann, Guillaume Lefèvre and Abdallah Hamze

Chinese Chemical Letters, 2023, 34, 107758
DOI: 10.1016/j.cclet.2022.107758

Expanding Ligand Space: Preparation, Characterization, and Synthetic Applications of Air-Stable, Odorless Di-tert-alkylphosphine Surrogates

Thomas Barber, Stephen P. Argent and Liam T. Ball

ACS Catal., 2020, 10, 5454
DOI: 10.1021/acscatal.0c01414

Synthesis of NHC-Iridium(III) Complexes Based on N-Iminoimidazolium Ylides and Their Use for the Amine Alkylation by Borrowing Hydrogen Catalysis

Vincent Guérin and Claude Y. Legault

Organometallics, 2021, 40, 408
DOI: 10.1021/acs.organomet.0c00726

Iron-Catalyzed Borrowing Hydrogen β-C(sp3)-Methylation of Alcohols

Kurt Polidano, Jonathan M. J. Williams and Louis C. Morrill

ACS Catal., 2019, 9, 8575
DOI: 10.1021/acscatal.9b02461

Catalytic Amination of Alcohols Using Diazo Compounds under Manganese Catalysis Through Hydrogenative N‐Alkylation Reaction

Reshma Babu, Subarna Sukanya Padhy, Rohit Kumar and Ekambaram Balaraman

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202302007

Alcohols as Substrates in Transition-Metal-Catalyzed Arylation, Alkylation, and Related Reactions

Adam Cook and Stephen G. Newman

Chem. Rev., 2024, 124, 6078
DOI: 10.1021/acs.chemrev.4c00094

Palladium-Catalyzed/Titanium-Promoted Csp3–Csp3 Coupling of Two Alcohols: Generation of an All-Carbon Quaternary Center

Huan Liu, Ziheng Jian, Min Zhang, Xiang Hao, Zehuai Mou, Huifei Wang and Hongbin Zhai

Org. Lett., 2025, 27, 3851
DOI: 10.1021/acs.orglett.5c00527

Borrowing Hydrogen and Acceptorless Dehydrogenative Coupling in the Multicomponent Synthesis of N‐Heterocycles: A Comparison between Base and Noble Metal Catalysis

Natalie Hofmann and Kai C. Hultzsch

Eur J Org Chem, 2021, 2021, 6206
DOI: 10.1002/ejoc.202100695

Synthesis of Rutaecarpine Analogues by Borrowing Hydrogen Strategy

Liangfeng Wang, Linfeng Zhang, Chao Zhou, Tiantian Gou, Nan‐Ying Chen, Ke Feng, Shiqing Li, Jun‐Cheng Su, Jingxian Yu, Guixia Wang and Xiangfei Kong

Adv Synth Catal, 2025, 367
DOI: 10.1002/adsc.202400698

Borrowing hydrogen activity of NH2-MIL-125 for N-alkylation of amines with alcohols under solvent and base free condition

Nisha B. Patel, Naresh Vala, Atindra Shukla, Subhadip Neogi and Manish Kumar Mishra

Catalysis Communications, 2020, 144, 106085
DOI: 10.1016/j.catcom.2020.106085

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