Julia L Finkelstein, Susannah Colt, Alexander J Layden, Jesse T Krisher, Anna M Stewart-Ibarra, Mark Polhemus, Efraín Beltrán-Ayala, Julia M Tedesco, Washington B Cárdenas, Timothy Endy and Saurabh Mehta

The Journal of Infectious Diseases, 2020, 221, 91
DOI: 10.1093/infdis/jiz427

Iron and Chelation in Biochemistry and Medicine: New Approaches to Controlling Iron Metabolism and Treating Related Diseases

George Kontoghiorghes and Christina Kontoghiorghe

Cells, 2020, 9, 1456
DOI: 10.3390/cells9061456

Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy‐Mediated Lysosomal ROS Generation

Tengfei Huang, Yanjie Sun, Yongli Li, Tingting Wang, Yun Fu, Cuiping Li, Changzheng Li and Julia M. dos Santos

Oxidative Medicine and Cellular Longevity, 2018, 2018
DOI: 10.1155/2018/4928703

Neuropathological and biochemical investigation of Hereditary Ferritinopathy cases with ferritin light chain mutation: Prominent protein aggregation in the absence of major mitochondrial or oxidative stress

M. Kurzawa‐Akanbi, M. Keogh, E. Tsefou, L. Ramsay, M. Johnson, S. Keers, L. WSA Ochieng, A. McNair, P. Singh, A. Khan, A. Pyle, G. Hudson, P. G. Ince, J. Attems, J. Burn, P. F. Chinnery and C. M. Morris

Neuropathology Appl Neurobio, 2021, 47, 26
DOI: 10.1111/nan.12634

Advanced approaches for improving bioavailability and controlled release of anthocyanins

Yixiao Shen, Ning Zhang, Jinlong Tian, Guang Xin, Ling Liu, Xiyun Sun and Bin Li

Journal of Controlled Release, 2022, 341, 285
DOI: 10.1016/j.jconrel.2021.11.031

Increased suicidal erythrocyte death in patients with hepatitis B-related acute-on-chronic liver failure

Cheng Mei, Fang Peng, Wenyu Yin, Wei Xu, Run Yao, Bijuan Li, Rongrong Zhou, Xuegong Fan and Ning Li

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2022, 323, G9
DOI: 10.1152/ajpgi.00050.2020

Iron Released after Cryo-Thermal Therapy Induced M1 Macrophage Polarization, Promoting the Differentiation of CD4+ T Cells into CTLs

Shicheng Wang, Man Cheng, Peng Peng, Yue Lou, Aili Zhang and Ping Liu

IJMS, 2021, 22, 7010
DOI: 10.3390/ijms22137010

The Vital Role Played by Deferiprone in the Transition of Thalassaemia from a Fatal to a Chronic Disease and Challenges in Its Repurposing for Use in Non-Iron-Loaded Diseases

George J. Kontoghiorghes

Pharmaceuticals, 2023, 16, 1016
DOI: 10.3390/ph16071016

Lysosomal iron recycling in mouse macrophages is dependent upon both LcytB and Steap3 reductases

Fanjing Meng, Brittany A. Fleming, Xuan Jia, Alexis A. Rousek, Matthew A. Mulvey and Diane M. Ward

Blood Advances, 2022, 6, 1692
DOI: 10.1182/bloodadvances.2021005609

Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases

Angamuthu Selvapandiyan, Niti Puri, Pankaj Kumar, Anwar Alam, Nasreen Zafar Ehtesham, George Griffin and Seyed Ehtesham Hasnain

FEMS Microbiology Reviews, 2023, 47
DOI: 10.1093/femsre/fuac041

Ascorbate and ferritin interactions: Consequences for iron release in vitro and in vivo and implications for inflammation

Charles Badu-Boateng and Richard J. Naftalin

Free Radical Biology and Medicine, 2019, 133, 75
DOI: 10.1016/j.freeradbiomed.2018.09.041

Trying to Solve the Puzzle of the Interaction of Ascorbic Acid and Iron: Redox, Chelation and Therapeutic Implications

George J. Kontoghiorghes, Annita Kolnagou, Christina N. Kontoghiorghe, Loukia Mourouzidis, Viktor A. Timoshnikov and Nikolay E. Polyakov

Medicines, 2020, 7, 45
DOI: 10.3390/medicines7080045

Iron as an immunometabolic signal in infection and inflammation

Alexander Hoffmann, Laura Homs Pérez and Günter Weiss

Front. Immunol., 2026, 17
DOI: 10.3389/fimmu.2026.1810718

Iron homeostasis and organismal aging

Rola S. Zeidan, Sung Min Han, Christiaan Leeuwenburgh and Rui Xiao

Ageing Research Reviews, 2021, 72, 101510
DOI: 10.1016/j.arr.2021.101510

New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases

Na Zhang, Xiaoqi Yu, Junxia Xie and Huamin Xu

Mol Neurobiol, 2021, 58, 2812
DOI: 10.1007/s12035-020-02277-7

Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology

Rikki A. M. Brown, Kirsty L. Richardson, Tasnuva D. Kabir, Debbie Trinder, Ruth Ganss and Peter J. Leedman

Front. Oncol., 2020, 10
DOI: 10.3389/fonc.2020.00476

Chemistry and biology of ferritin

Marina Plays, Sebastian Müller and Raphaël Rodriguez

Metallomics, 2021, 13
DOI: 10.1093/mtomcs/mfab021

The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells

Danielle K. Bailey, Whitney Clark, Daniel J. Kosman and Kostas Pantopoulos

PLoS ONE, 2021, 16, e0254794
DOI: 10.1371/journal.pone.0254794

Advances in Ferritin Physiology and Possible Implications in Bacterial Infection

Clemens M. Gehrer, Anna-Maria Mitterstiller, Philipp Grubwieser, Esther G. Meyron-Holtz, Günter Weiss and Manfred Nairz

IJMS, 2023, 24, 4659
DOI: 10.3390/ijms24054659

The emerging roles of eryptosis in liver diseases

Wei Xu, Fang Peng, Ying Deng, Xuegong Fan and Ning Li

Transfusion Clinique et Biologique, 2019, 26, 336
DOI: 10.1016/j.tracli.2019.05.004

Kinetic Modeling of pH-Dependent Oxidation of Dopamine by Iron and Its Relevance to Parkinson's Disease

Yingying Sun, A. Ninh Pham, Dominic J. Hare and T. David Waite

Front. Neurosci., 2018, 12
DOI: 10.3389/fnins.2018.00859

New Era in the Treatment of Iron Deficiency Anaemia Using Trimaltol Iron and Other Lipophilic Iron Chelator Complexes: Historical Perspectives of Discovery and Future Applications

George Kontoghiorghes, Annita Kolnagou, Theodora Demetriou, Marina Neocleous and Christina Kontoghiorghe

IJMS, 2021, 22, 5546
DOI: 10.3390/ijms22115546

Nitric oxide enhances in-vitro caulogenesis in Linum usitatissimum L. (Linaceae) by facilitating iron mobilization

Charu Kalra, Latif Ahmad Peer, Durukhshan Zehra, Bilal Ahmad Mir and Shashi Bhushan Babbar

Plant Cell Tiss Organ Cult, 2025, 162
DOI: 10.1007/s11240-025-03138-8

Current understanding of eryptosis: mechanisms, physiological functions, role in disease, pharmacological applications, and nomenclature recommendations

Anton Tkachenko, Mohammad A. Alfhili, Jawaher Alsughayyir, Alessandro Attanzio, Abdulla Al Mamun Bhuyan, Bożena Bukowska, Antonio Cilla, Martha A. Quintanar-Escorza, Michael Föller, Ondrej Havranek, Kashif Jilani, Anatolii Onishchenko, Etheresia Pretorius, Volodymyr Prokopiuk, Ignazio Restivo, Luisa Tesoriere, Grazia Maria Virzì and Thomas Wieder

Cell Death Dis, 2025, 16
DOI: 10.1038/s41419-025-07784-w

The Interplay of Ascorbic Acid with Quinones-Chelators—Influence on Lipid Peroxidation: Insight into Anticancer Activity

Olga Yu. Selyutina, Polina A. Kononova, Vladimir E. Koshman, Lidiya G. Fedenok and Nikolay E. Polyakov

Antioxidants, 2022, 11, 376
DOI: 10.3390/antiox11020376

HCV-Induced Immunometabolic Crosstalk in a Triple-Cell Co-Culture Model Capable of Simulating Systemic Iron Homeostasis

Pelagia Foka, Alexios Dimitriadis, Eirini Karamichali, Emmanouil Kochlios, Petros Eliadis, Vaia Valiakou, John Koskinas, Avgi Mamalaki and Urania Georgopoulou

Cells, 2021, 10, 2251
DOI: 10.3390/cells10092251

Hypoxia-responsive nanoreactors based on self-enhanced photodynamic sensitization and triggered ferroptosis for cancer synergistic therapy

Xiaoyan Wang, Ming Wu, Xiaolong Zhang, Feida Li, Yongyi Zeng, Xinyi Lin, Xiaolong Liu and Jingfeng Liu

J Nanobiotechnol, 2021, 19
DOI: 10.1186/s12951-021-00952-y

Cryo-EM structures and functional characterization of homo- and heteropolymers of human ferritin variants

Jose Irimia-Dominguez, Chen Sun, Kunpeng Li, Barry B. Muhoberac, Grace I. Hallinan, Holly J. Garringer, Bernardino Ghetti, Wen Jiang and Ruben Vidal

Sci Rep, 2020, 10
DOI: 10.1038/s41598-020-77717-4

Iron metabolism: pathways and proteins in homeostasis

Ekta Kundra Arora and Vibha Sharma

Reviews in Inorganic Chemistry, 2023, 43, 523
DOI: 10.1515/revic-2022-0031

Improving the Gastric Resilience of Ferritin Nanocages by Fabrication with Gelatin for the Development of Oral Iron Supplements

Rohit Kumar Raut, Gargee Bhattacharyya, Swagatika Mallik and Rabindra K. Behera

ChemBioChem, 2025, 26
DOI: 10.1002/cbic.202500620

Hyperthermia/glutathione-triggered ferritin nanoparticles amplify the ferroptosis for synergistic tumor therapy

Yiting Chen, Xinhong Li, Kuankuan Luo, Tao Wang, Tongyao Liu, Enhao Lu, Rui Wang, Yu Luo and Xianyi Sha

Materials Today Bio, 2024, 26, 101085
DOI: 10.1016/j.mtbio.2024.101085

Critical Role for Molecular Iron in Coxiella burnetii Replication and Viability

Savannah E. Sanchez, Anders Omsland and Sarah E. F. D’Orazio

mSphere, 2020, 5
DOI: 10.1128/msphere.00458-20

Development of a colorimetric assay for quantification of favipiravir in human serum using ferrihydrite

Yukiko Moriiwa, Natsu Oyama, Ryo Otsuka, Kazuhiro Morioka, Atsushi Shoji and Akio Yanagida

Talanta, 2023, 252, 123827
DOI: 10.1016/j.talanta.2022.123827

Iron and manganese transport in mammalian systems

Qingli Liu, Saiid Barker and Mitchell D. Knutson

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2021, 1868, 118890
DOI: 10.1016/j.bbamcr.2020.118890

Regulation of Intestinal Iron Absorption: Balancing Supply and Demand

Shazia Yaseen, Rai Hamza Akram, Basit Ali, Komal Zaheer, Memoona Rafique, Pakeeza Eman, Namal Fatima, Fazeelat Kausar and Muhammad Luqman

FBT, 2024, 02
DOI: 10.54393/fbt.v4i03.149

The Importance and Essentiality of Natural and Synthetic Chelators in Medicine: Increased Prospects for the Effective Treatment of Iron Overload and Iron Deficiency

George J. Kontoghiorghes

IJMS, 2024, 25, 4654
DOI: 10.3390/ijms25094654

In Vitro Iron Release From Intact Ferritin Protein Nanocages: Impact of Physiological Reducing Agents and the Ascorbate‐Quinone Redox Couple

Narmada Behera, Gargee Bhattacharyya and Rabindra K. Behera

Chemistry An Asian Journal, 2025, 20
DOI: 10.1002/asia.202500803

Protein nanoparticle cellular fate and responses in murine macrophages

Samyukta Ravishankar, Anu Maashaa Nedumaran, Archana Gautam, Kee Woei Ng, Bertrand Czarny and Sierin Lim

NPG Asia Mater, 2023, 15
DOI: 10.1038/s41427-022-00453-w

Targeting Aging and Diseases Associated with Ferroptosis and Senescence Through Modulation of Iron, Oxidative Stress and Lipid Peroxidation

Malamati Kourti and George J. Kontoghiorghes

Antioxidants, 2025, 15, 15
DOI: 10.3390/antiox15010015

Iron Mobilization from Ferritin in Yeast Cell Lysate and Physiological Implications

Gideon L. Smith, Ayush K. Srivastava, Aliaksandra A. Reutovich, Nathan J. Hunter, Paolo Arosio, Artem Melman and Fadi Bou-Abdallah

IJMS, 2022, 23, 6100
DOI: 10.3390/ijms23116100

Storage and transport of labile iron is mediated by lysosomes in axons and dendrites of hippocampal neurons

Aiyarin Kittilukkana, Asuncion Carmona, Léa Normand, Coline Gibout, Andrea Somogyi, Chalermchai Pilapong and Richard Ortega

Metallomics, 2025, 17
DOI: 10.1093/mtomcs/mfaf021