ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus

Daniela Coppola, Stefania Abbruzzetti, Francesco Nicoletti, Antonello Merlino, Alessandra Gambacurta, Daniela Giordano, Barry D. Howes, Giampiero De Sanctis, Luigi Vitagliano, Stefano Bruno, Guido di Prisco, Lelio Mazzarella, Giulietta Smulevich, Massimo Coletta, Cristiano Viappiani, Alessandro Vergara and Cinzia Verde

Mol. BioSyst., 2012, 8, 3295
DOI: 10.1039/c2mb25210d

Introducing the Time-resolved methods in biophysics series

Thomas Gensch and Cristiano Viappiani

Photochem Photobiol Sci, 2006, 5, 1101
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Photodynamic action of Hypericum perforatum hydrophilic extract against Staphylococcus aureus

Pietro Delcanale, Cormac Hally, Santi Nonell, Silvia Bonardi, Cristiano Viappiani and Stefania Abbruzzetti

Photochem Photobiol Sci, 2020, 19, 324
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Tuning the local solvent composition at a drug carrier surface: the effect of dimethyl sulfoxide/water mixture on the photofunctional properties of hypericin–β-lactoglobulin complexes

P. Delcanale, B. Rodríguez-Amigo, J. Juárez-Jiménez, F. J. Luque, S. Abbruzzetti, M. Agut, S. Nonell and C. Viappiani

J. Mater. Chem. B, 2017, 5, 1633
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Time-resolved methods in biophysics. 9. Laser temperature-jump methods for investigating biomolecular dynamics

Jan Kubelka

Photochem Photobiol Sci, 2009, 8, 499
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Ligand migration through hemeprotein cavities: insights from laser flash photolysis and molecular dynamics simulations

Stefania Abbruzzetti, Francesca Spyrakis, Axel Bidon-Chanal, F. Javier Luque and Cristiano Viappiani

Phys. Chem. Chem. Phys., 2013, 15, 10686
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Photoswitching of E222Q GFP mutants: “concerted” mechanism of chromophore isomerization and protonation

Stefania Abbruzzetti, Ranieri Bizzarri, Stefano Luin, Riccardo Nifosì, Barbara Storti, Cristiano Viappiania and Fabio Beltram

Photochem Photobiol Sci, 2010, 9, 1307
DOI: 10.1039/c0pp00189a

A caged cyanide

Markus Knipp, Johanna J. Taing, Chunmao He and Cristiano Viappiani

Photochem Photobiol Sci, 2012, 11, 620
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Infrared Difference Spectroscopy of Proteins: From Bands to Bonds

Victor A. Lorenz-Fonfria

Chem. Rev., 2020, 120, 3466
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Unusually Fast bis-Histidyl Coordination in a Plant Hemoglobin

Stefania Abbruzzetti, Alex J. Barker, Irene Villar, Carmen Pérez-Rontomé, Stefano Bruno, Giulio Cerullo, Cristiano Viappiani and Manuel Becana

IJMS, 2021, 22, 2740
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Heterogeneous Kinetics of the Carbon Monoxide Association and Dissociation Reaction to Nitrophorin 4 and 7 Coincide with Structural Heterogeneity of the Gate-Loop

Stefania Abbruzzetti, Chunmao He, Hideaki Ogata, Stefano Bruno, Cristiano Viappiani and Markus Knipp

J. Am. Chem. Soc., 2012, 134, 9986
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Versatile Supramolecular Complex for Targeted Antimicrobial Photodynamic Inactivation

Andrea Mussini, Eleonora Uriati, Cormac Hally, Santi Nonell, Paolo Bianchini, Alberto Diaspro, Stefano Pongolini, Pietro Delcanale, Stefania Abbruzzetti and Cristiano Viappiani

Bioconjugate Chem., 2022, 33, 666
DOI: 10.1021/acs.bioconjchem.2c00067

Oxygen and nitric oxide rebinding kinetics in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana

Stefania Abbruzzetti, Serena Faggiano, Francesca Spyrakis, Stefano Bruno, Andrea Mozzarelli, Alessandra Astegno, Paola Dominici and Cristiano Viappiani

IUBMB Life, 2011, 63, 1094
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Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus

Laura Calvo-Begueria, Bert Cuypers, Sabine Van Doorslaer, Stefania Abbruzzetti, Stefano Bruno, Herald Berghmans, Sylvia Dewilde, Javier Ramos, Cristiano Viappiani and Manuel Becana

Front. Plant Sci., 2017, 8
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Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana

Francesca Spyrakis, Serena Faggiano, Stefania Abbruzzetti, Paola Dominici, Elena Cacciatori, Alessandra Astegno, Enrica Droghetti, Alessandro Feis, Giulietta Smulevich, Stefano Bruno, Andrea Mozzarelli, Pietro Cozzini, Cristiano Viappiani, A. Bidon-Chanal and F. Javier Luque

J. Phys. Chem. B, 2011, 115, 4138
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Ligand Migration and Binding in Nonsymbiotic Hemoglobins of Arabidopsis thaliana

Karin Nienhaus, Paola Dominici, Alessandra Astegno, Stefania Abbruzzetti, Cristiano Viappiani and G. Ulrich Nienhaus

Biochemistry, 2010, 49, 7448
DOI: 10.1021/bi100768g

CO Rebinding Kinetics and Molecular Dynamics Simulations Highlight Dynamic Regulation of Internal Cavities in Human Cytoglobin

Matteo Gabba, Stefania Abbruzzetti, Francesca Spyrakis, Flavio Forti, Stefano Bruno, Andrea Mozzarelli, F. Javier Luque, Cristiano Viappiani, Pietro Cozzini, Marco Nardini, Francesca Germani, Martino Bolognesi, Luc Moens, Sylvia Dewilde and Vladimir N. Uversky

PLoS ONE, 2013, 8, e49770
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Ligand migration and hexacoordination in type 1 non-symbiotic rice hemoglobin

Nitin Kumar Bisht, Stefania Abbruzzetti, Sheetal Uppal, Stefano Bruno, Francesca Spyrakis, Andrea Mozzarelli, Cristiano Viappiani and Suman Kundu

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2011, 1814, 1042
DOI: 10.1016/j.bbapap.2010.09.016

Photoswitching of Enzyme Activity by Laser-Induced pH-Jump

Stefanie Kohse, Antje Neubauer, Alexandra Pazidis, Stefan Lochbrunner and Udo Kragl

J. Am. Chem. Soc., 2013, 135, 9407
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Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7

Markus Knipp, Hideaki Ogata, Giancarlo Soavi, Giulio Cerullo, Alessandro Allegri, Stefania Abbruzzetti, Stefano Bruno, Cristiano Viappiani, Axel Bidon-Chanal and F. Javier Luque

F1000Res, 2015, 4, 45
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Structural analysis in nonsymbiotic hemoglobins: What can we learn from inner cavities?

Francesca Spyrakis, F. Javier Luque and Cristiano Viappiani

Plant Science, 2011, 181, 8
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Cold-Adaptation Signatures in the Ligand Rebinding Kinetics to the Truncated Hemoglobin of the Antarctic Bacterium Pseudoalteromonas haloplanktis TAC125

Fernando M. Boubeta, Leonardo Boechi, Dario Estrin, Barbara Patrizi, Mariangela Di Donato, Alessandro Iagatti, Daniela Giordano, Cinzia Verde, Stefano Bruno, Stefania Abbruzzetti and Cristiano Viappiani

J. Phys. Chem. B, 2018, 122, 11649
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Ligation Tunes Protein Reactivity in an Ancient Haemoglobin: Kinetic Evidence for an Allosteric Mechanism in Methanosarcina acetivorans Protoglobin

Stefania Abbruzzetti, Lesley Tilleman, Stefano Bruno, Cristiano Viappiani, Filip Desmet, Sabine Van Doorslaer, Massimo Coletta, Chiara Ciaccio, Paolo Ascenzi, Marco Nardini, Martino Bolognesi, Luc Moens, Sylvia Dewilde and Vladimir N. Uversky

PLoS ONE, 2012, 7, e33614
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Mycobacterial and Human Ferrous Nitrobindins: Spectroscopic and Reactivity Properties

Giovanna De Simone, Alessandra di Masi, Alessandra Pesce, Martino Bolognesi, Chiara Ciaccio, Lorenzo Tognaccini, Giulietta Smulevich, Stefania Abbruzzetti, Cristiano Viappiani, Stefano Bruno, Sara Della Monaca, Donatella Pietraforte, Paola Fattibene, Massimo Coletta and Paolo Ascenzi

IJMS, 2021, 22, 1674
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PEGylation Promotes Hemoglobin Tetramer Dissociation

Dario Caccia, Luca Ronda, Raffaella Frassi, Michele Perrella, Elena Del Favero, Stefano Bruno, Barbara Pioselli, Stefania Abbruzzetti, Cristiano Viappiani and Andrea Mozzarelli

Bioconjugate Chem., 2009, 20, 1356
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Structural and functional properties of Antarctic fish cytoglobins-1: Cold-reactivity in multi-ligand reactions

Daniela Giordano, Alessandra Pesce, Stijn Vermeylen, Stefania Abbruzzetti, Marco Nardini, Francesco Marchesani, Herald Berghmans, Constantí Seira, Stefano Bruno, F. Javier Luque, Guido di Prisco, Paolo Ascenzi, Sylvia Dewilde, Martino Bolognesi, Cristiano Viappiani and Cinzia Verde

Computational and Structural Biotechnology Journal, 2020, 18, 2132
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Comparative analysis of inner cavities and ligand migration in non-symbiotic AHb1 and AHb2

Francesca Spyrakis, Fátima Lucas, Axel Bidon-Chanal, Cristiano Viappiani, Victor Guallar and F. Javier Luque

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013, 1834, 1957
DOI: 10.1016/j.bbapap.2013.04.003

Nanosecond Diffuse Reflectance Spectroscopy for In-Situ Analysis of Electron Back-Recombination and Dye Regeneration in Fully Functional, Highly Efficient, Opaque Dye-Sensitized Solar Cell Devices

Elham Ghadiri and Jacques-E. Moser

J. Phys. Chem. C, 2023, 127, 23285
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The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties

Roberta Russo, Daniela Giordano, Gianluca Paredi, Francesco Marchesani, Lisa Milazzo, Giovanna Altomonte, Pietro Del Canale, Stefania Abbruzzetti, Paolo Ascenzi, Guido di Prisco, Cristiano Viappiani, Angela Fago, Stefano Bruno, Giulietta Smulevich, Cinzia Verde and Jodie L. Rummer

PLoS ONE, 2017, 12, e0186181
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Following Ligand Migration Pathways from Picoseconds to Milliseconds in Type II Truncated Hemoglobin from Thermobifida fusca

Agnese Marcelli, Stefania Abbruzzetti, Juan Pablo Bustamante, Alessandro Feis, Alessandra Bonamore, Alberto Boffi, Cristina Gellini, Pier Remigio Salvi, Dario A. Estrin, Stefano Bruno, Cristiano Viappiani, Paolo Foggi and Nikolai Lebedev

PLoS ONE, 2012, 7, e39884
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Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides

Daniela Coppola, Daniela Giordano, Stefania Abbruzzetti, Francesco Marchesani, Marco Balestrieri, Guido di Prisco, Cristiano Viappiani, Stefano Bruno and Cinzia Verde

Hydrobiologia, 2015, 761, 315
DOI: 10.1007/s10750-015-2439-2

Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana

Stefano Bruno, Serena Faggiano, Francesca Spyrakis, Andrea Mozzarelli, Elena Cacciatori, Paola Dominici, Elena Grandi, Stefania Abbruzzetti and Cristiano Viappiani

Gene, 2007, 398, 224
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Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans

Lesley Tilleman, Stefania Abbruzzetti, Chiara Ciaccio, Giampiero De Sanctis, Marco Nardini, Alessandra Pesce, Filip Desmet, Luc Moens, Sabine Van Doorslaer, Stefano Bruno, Martino Bolognesi, Paolo Ascenzi, Massimo Coletta, Cristiano Viappiani, Sylvia Dewilde and Shannon Wing-Ngor Au

PLoS ONE, 2015, 10, e0125959
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Zinc-Substituted Myoglobin Is a Naturally Occurring Photo-antimicrobial Agent with Potential Applications in Food Decontamination

Pietro Delcanale, Chiara Montali, Beatriz Rodríguez-Amigo, Stefania Abbruzzetti, Stefano Bruno, Paolo Bianchini, Alberto Diaspro, Montserrat Agut, Santi Nonell and Cristiano Viappiani

J. Agric. Food Chem., 2016, 64, 8633
DOI: 10.1021/acs.jafc.6b03368

Evolutionary and Functional Relationships in the Truncated Hemoglobin Family

Juan P. Bustamante, Leandro Radusky, Leonardo Boechi, Darío A. Estrin, Arjen ten Have, Marcelo A. Martí and Ozlem Keskin

PLoS Comput Biol, 2016, 12, e1004701
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Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7

Stefania Abbruzzetti, Alessandro Allegri, Axel Bidon-Chanal, Hideaki Ogata, Giancarlo Soavi, Giulio Cerullo, Stefano Bruno, Chiara Montali, F. Javier Luque and Cristiano Viappiani

Sci Rep, 2018, 8
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Surprising differences in the respiratory protein of insects: A spectroscopic study of haemoglobin from the European honeybee and the malaria mosquito

Kevin Nys, Bert Cuypers, Herald Berghmans, Dietmar Hammerschmid, Luc Moens, Sylvia Dewilde and Sabine Van Doorslaer

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020, 1868, 140413
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Concanavalin A Delivers a Photoactive Protein to the Bacterial Wall

Andrea Mussini, Pietro Delcanale, Melissa Berni, Stefano Pongolini, Mireia Jordà-Redondo, Montserrat Agut, Peter J. Steinbach, Santi Nonell, Stefania Abbruzzetti and Cristiano Viappiani

IJMS, 2024, 25, 5751
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Labeling and Selective Inactivation of Gram‐Positive Bacteria Employing Bimodal Photoprobes with Dual Readouts

Anzhela Galstyan, Desiree Block, Silke Niemann, Malte C. Grüner, Stefania Abbruzzetti, Michele Oneto, Constantin G. Daniliuc, Sven Hermann, Cristiano Viappiani, Michael Schäfers, Bettina Löffler, Cristian A. Strassert and Andreas Faust

Chemistry A European J, 2016, 22, 5243
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Serum albumins are efficient delivery systems for the photosensitizer hypericin in photosensitization-based treatments against Staphylococcus aureus

Denise Pezzuoli, Marco Cozzolino, Chiara Montali, Lorenzo Brancaleon, Paolo Bianchini, Marta Zantedeschi, Silvia Bonardi, Cristiano Viappiani and Stefania Abbruzzetti

Food Control, 2018, 94, 254
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Engineered chimeras reveal the structural basis of hexacoordination in globins: A case study of neuroglobin and myoglobin

Ignacio Boron, Luciana Capece, Francesca Pennacchietti, Diana E. Wetzler, Stefano Bruno, Stefania Abbruzzetti, Lucía Chisari, F. Javier Luque, Cristiano Viappiani, Marcelo A. Marti, Dario A. Estrin and Alejandro D. Nadra

Biochimica et Biophysica Acta (BBA) - General Subjects, 2015, 1850, 169
DOI: 10.1016/j.bbagen.2014.10.006

Ligand migration through the internal hydrophobic cavities in human neuroglobin

Stefania Abbruzzetti, Serena Faggiano, Stefano Bruno, Francesca Spyrakis, Andrea Mozzarelli, Sylvia Dewilde, Luc Moens and Cristiano Viappiani

Proc. Natl. Acad. Sci. U.S.A., 2009, 106, 18984
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Ligand-Induced Tertiary Relaxations During the T-to-R Quaternary Transition in Hemoglobin

Luca Ronda, Stefania Abbruzzetti, Stefano Bruno, Stefano Bettati, Andrea Mozzarelli and Cristiano Viappiani

J. Phys. Chem. B, 2008, 112, 12790
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The optical spectra of fluoride complexes can effectively probe H-bonding interactions in the distal cavity of heme proteins

Enrica Droghetti, Francesco P. Nicoletti, Alessandra Bonamore, Natascia Sciamanna, Alberto Boffi, Alessandro Feis and Giulietta Smulevich

Journal of Inorganic Biochemistry, 2011, 105, 1338
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Kinetics and computational studies of ligand migration in nitrophorin 7 and its Δ1–3 mutant

Ana Oliveira, Alessandro Allegri, Axel Bidon-Chanal, Markus Knipp, Adrian E. Roitberg, Stefania Abbruzzetti, Cristiano Viappiani and F. Javier Luque

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013, 1834, 1711
DOI: 10.1016/j.bbapap.2013.04.009

Apomyoglobin is an efficient carrier for zinc phthalocyanine in photodynamic therapy of tumors

Marco Cozzolino, Luca Pesce, Denise Pezzuoli, Chiara Montali, Lorenzo Brancaleon, Luigi Cavanna, Stefania Abbruzzetti, Alberto Diaspro, Paolo Bianchini and Cristiano Viappiani

Biophysical Chemistry, 2019, 253, 106228
DOI: 10.1016/j.bpc.2019.106228

Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins

Juan P. Bustamante, Stefania Abbruzzetti, Agnese Marcelli, Diego Gauto, Leonardo Boechi, Alessandra Bonamore, Alberto Boffi, Stefano Bruno, Alessandro Feis, Paolo Foggi, Dario A. Estrin and Cristiano Viappiani

J. Phys. Chem. B, 2014, 118, 1234
DOI: 10.1021/jp410724z

Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes

Daniela Coppola, Stefano Bruno, Luca Ronda, Cristiano Viappiani, Stefania Abbruzzetti, Guido di Prisco, Cinzia Verde and Andrea Mozzarelli

BMC Biochem, 2011, 12
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Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7

Markus Knipp, Hideaki Ogata, Giancarlo Soavi, Giulio Cerullo, Alessandro Allegri, Stefania Abbruzzetti, Stefano Bruno, Cristiano Viappiani, Axel Bidon-Chanal and F. Javier Luque

F1000Res, 2015, 4, 45
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