Issue 18, 2025

Visible-light irradiation of chalcones: expanding the scope of photocatalysis

Abstract

Chalcones, an important class of α,β-unsaturated compounds, have garnered significant attention because of their pharmacological and biological importance. Due to their exceptional redox properties and triplet energy state, visible-light irradiation of chalcones can profoundly impact their reactivity, opening novel avenues for synthetic applications. In this review, a comprehensive overview of visible-light irradiation of chalcones has been presented, along with the underlying mechanisms involved and the resulting transformations. By elucidating the complex interplay between visible light and chalcone reactivity, this review seeks to inspire researchers working in the field of medicinal chemistry, asymmetric catalysis, and photochemical and sustainable organic synthesis.

Graphical abstract: Visible-light irradiation of chalcones: expanding the scope of photocatalysis

Article information

Article type
Review Article
Submitted
17 dec. 2024
Accepted
02 apr. 2025
First published
04 apr. 2025

Org. Biomol. Chem., 2025,23, 4306-4332

Visible-light irradiation of chalcones: expanding the scope of photocatalysis

D. Goswami, B. Sarma and B. Dam, Org. Biomol. Chem., 2025, 23, 4306 DOI: 10.1039/D4OB02037E

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