Microbial skeletal editing: hints for arene reconstruction from actinobacteria

Viktoria A. Ikonnikova, Vera A. Alferova, Anastasiya Yu. Frolova, Mikhail S. Baranov and Andrey A. Mikhaylov

Nat. Prod. Rep., 2026, 43, 518
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Transition metal/photocatalyst-free skeletal editing of indene with iodonium difluorodiazo reagent to access 2-(difluoromethyl)naphthalene

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Chem. Commun., 2025, 61, 8667
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Remodelling molecular frameworks via atom-level surgery: recent advances in skeletal editing of (hetero)cycles

Rubal Sharma, Mitsuhiro Arisawa, Shinobu Takizawa and Mohamed S. H. Salem

Org. Chem. Front., 2025, 12, 1633
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Molecular editing of 3-hydroxyphenyl oxindole derivatives via formal O-insertion and N-insertion: synthesis of dioxolane spirooxindoles and quinoxalin-2(1H)-ones

Yao-Bin Shen, Jia-Wei Li, Peng Wang, Houchen Wang, Tiesheng Shi, Fangzhi Hu and Shuai-Shuai Li

Org. Chem. Front., 2026, 13, 251
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Transition-metal-free skeletal editing of five- and six-membered N-heterocycles

Liling Pan, Yong Huang, Xiaoqiang Sun and Ke Yang

Chem. Commun., 2026
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A difluorocarbene-triggered annulation/ring expansion cascade via sequential single-atom-insertions: direct assembly of 2-fluoroquinazolinones from azo compounds

Yingxian Tian, Yiyan Xiong, Jingyu Wei, Gongming Zhu, Junbiao Chang and Bingxian Liu

Chem. Sci., 2026, 17, 8136
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Single-atom editing for the construction of boron-containing heterocycles

Xue Li, Yi-Ming Chen and Zhi-Gang Xu

Org. Chem. Front., 2025, 12, 3521
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Cyclopropanation vs. single-carbon insertion of pyrrole-2,3-diones with sulfonium ylides: synthesis of functionalized 2-azabicyclo[3.1.0]hexanes and pyridine-2,3-diones

Maria M. Muranova, Andrey R. Galeev, Andrey N. Maslivets and Maksim V. Dmitriev

Org. Chem. Front., 2025, 12, 2187
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Metal-Catalyzed Fluoroacetyl Carbene Transfer from Sulfonium Salts

Arturs Sperga, Artis Kinens and Janis Veliks

Org. Lett., 2025, 27, 5446
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Energy-Transfer-Enabled 1,4-Amino Migration and C–O Diradical Recombination for Norrish–Yang-Type Epoxidation

Dan-Na Chen, Lu-Lu Qin, Di-Jing Luo, Yu Lv, Hong-Yu Yang, Dan-Dan Ye and Peng-Ju Xia

Org. Lett., 2025, 27, 5744
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Remodeling of the Indole Ring with Redistribution of the C2 Atom: Switchable Access to Phenanthridines and Phenanthridine N‐Oxides

Li Yang, Cheng Xu, Zheng Liu, Lijing Zhong, Qing Wang, Qian Shu, Shui Qian, Rongchuan Su, Guodong Yin and Ge Gao

Chin. J. Chem., 2025, 43, 2729
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Carbene Insertion and Furyl Migration Cascade Toward Benzofurans

Tu Zeng, Shiqing Huang, Yingjian Gong, Li Li, Keyi Guo, Shitian Wu, Huiyang Zhan, Shiyu Xu, Xingcan Zhang and Baosheng Li

Angew Chem Int Ed, 2025, 64
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Skeletal Editing of Benzodithiol‐3‐ones via S‐to‐C Atom Swap

Xiaobing Liu, Xuan Kong, Jing Zheng, Jiayuan Zhou, Jinghui Wen, Yao Zhou, Shengzhou Jin and Guodong Yin

Chin. J. Chem., 2026, 44, 251
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Advancing Total Synthesis Through Skeletal Editing

Reem Al-Ahmad and Mingji Dai

Acc. Chem. Res., 2025, 58, 1392
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Ring Cleavage for Ring Construction: Oxidative Heterocyclic Segregation toward Tribenzophenanthrolines

Takanori Suzuki, Kota Asai, Takeru Saito, Johnny Hu, Takuya Shimajiri and Yusuke Ishigaki

Chemistry A European J, 2025, 31
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Single‐Atom Skeletal Editing of Aromatics: Advances in Carbon‐to‐Nitrogen and Nitrogen‐to‐Carbon Transmutation

Ankit Kachore, Varun Aggarwal, Ekta Bala, Hemant Singh, Manickam Selvaraj, Mohammed A. Assiri, Saima, Rakesh Kumar and Praveen Kumar Verma

Eur J Org Chem, 2026, 29
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Precisely Skeletal Reorganization via Single Carbon Atom Insertion

Bing‐Chao Da, Shao‐Hua Xiang, Junmin Zhang and Bin Tan

Chin. J. Chem., 2026, 44, 1865
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The Cargill-Type Rearrangement in Natural Product Synthesis

Wen Xun, Deyun Ma, Rimeng Chen, Shaobin Su and Bo Xu

Synthesis, 2025, 57, 2765
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Anomeric Amides: Valuable Reagents in Synthetic Organic Chemistry

Arushi Garg, Jordan Vigier, Hélène Lebel and Tatiana Besset

Angewandte Chemie, 2026, 138
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Skeletal recasting of benzo[c][1,2]dithiol-3-ones for the construction of 3-hydroxybenzo[b]thiophenes

Xuan Kong, Jing Zheng, Zhengheng Li, Yuan Yin, Yushang Qin and Yao Zhou

Green Synthesis and Catalysis, 2025
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Skeletal Editing through Cycloaddition and Subsequent Cycloreversion Reactions

Pengwei Xu and Armido Studer

Acc. Chem. Res., 2025, 58, 647
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Controllable Molecular Editing of 2-Amino-N-substituted Benzamides: Site-selective Synthesis of 6-Selenylated N-Substituted 1,2,3-Benzotriazine-4(3H)-ones

Yatang Wang, Xiaofeng Hua, Yinyin Li, Zhiying Zhang, Yinyun Lin, Wei Guo and Lvyin Zheng

Org. Lett., 2025, 27, 1441
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Visible Light‐Induced Single‐Atom Insertion of Indenes via Aerobic Ring Scission–Condensation–Rearomatization

Guohui Zeng, Zeyuan Fu, Biaolin Yin and Liangbin Huang

Chemistry A European J, 2025, 31
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Dual Cobalt/Photoredox Catalysis for the Synthesis of α,β-Unsaturated γ-Lactams and α-Enaminones

Wei-Qian Fan, Shi-Qing Zhang, Sheng Du, Yi-Bin Zhang, Ming-Qi Yang, Ying Tong, Ya-Ge Zheng, Jing-Yi Jia, Chao Deng and Wen-Ting Wei

Org. Lett., 2026, 28, 1487
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Anomeric Amides: Valuable Reagents in Synthetic Organic Chemistry

Arushi Garg, Jordan Vigier, Hélène Lebel and Tatiana Besset

Angew Chem Int Ed, 2026, 65
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Unimolecular Fragment Coupling and Single Carbon Atom Doping as Tools for Structural Reprogramming

Hayato Fujimoto and Mamoru Tobisu

Acc. Chem. Res., 2025, 58, 1168
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Pyrone Isomerization Enabled Divergent Access to Multisubstituted Biaryl Phenol via Relay Claisen Rearrangement

Jialin Wang, Mingluo He, Tongxiang Cao and Shifa Zhu

Org. Lett., 2025, 27, 4865
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Carbene Insertion and Furyl Migration Cascade Toward Benzofurans

Tu Zeng, Shiqing Huang, Yingjian Gong, Li Li, Keyi Guo, Shitian Wu, Huiyang Zhan, Shiyu Xu, Xingcan Zhang and Baosheng Li

Angewandte Chemie, 2025, 137
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Synthesis of indolizines via Pd-catalyzed selective ring recasting of oxazolidines with deesterification of methyl acrylates

Ya Pan, Xianjun Xu, Junwei Li, Luosang Cuomu, Erik V. Van der Eycken and Huangdi Feng

Sustainable Chemistry and Pharmacy, 2025, 46, 102059
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Skeletal editing of C(sp3)–C(sp3) bonds via photoinduced oxidative oxygen migration

Ajay H. Bansode and Marvin Parasram

Nat. Synth, 2025, 5, 316
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Skeletal Editing of Alkenes and Alkynes via Single‐Carbon‐Atom Insertion

Wei Jiang, Yaxin Fan, Fukuan Zhang, Mengya Yin, Yu Zhang and Yaojia Jiang

Chemistry A European J, 2025, 31
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Ring Expansion of Benzofurans by Single-Silicon Insertion

Qiuling Yan, Hongxia Song, Hong Lu and Hao Wei

J. Am. Chem. Soc., 2026, 148, 12486
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Scaffold Hopping of α,β-Unsaturated Ketones via Divergent Alkyl Amine Insertion

Huiguang Yu, Lili Xu, Luyao Li and Chang Min

J. Am. Chem. Soc., 2025, 147, 26584
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Synthesis of Dibenzo[a,c]phenazines through Brønsted Acid-Catalyzed Skeletal Editing of 2-Arylindoles with 1,2-Diaminoarenes

Kun Li, Hai-Fang Lin, Hong-Yan Bi, Wei-Min Shi, Xiao-Pan Ma and Dong-Liang Mo

Org. Lett., 2025, 27, 11596
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