Interaction of Au(iii) with amino acids: a vade mecum for medicinal chemistry and nanotechnology

Edoardo Jun Mattioli, Beatrice Cipriani, Francesco Zerbetto, Tainah Dorina Marforio and Matteo Calvaresi

J. Mater. Chem. B, 2024, 12, 5162
DOI: 10.1039/D4TB00204K

Therapeutic Potential of PDA@CeO2 in Suppressing Hepatic Stellate Cell Activation and Preventing Liver Fibrosis

Han-mei Li, Ju-ying Zhang, Xiao-qing Wang, Li-tao Ye, Bo Ren, Yi-han Leng, Ji-xuan Zhang, You Yang, Qiong Jiang, Lin-li Feng, Yang Li and Jin-hong Yu

IJN, 2025, Volume 20, 9073
DOI: 10.2147/IJN.S521372

Deacetylasperulosidic acid methyl ester attenuates liver fibrosis by modulating the SCFAs-Wnt/β-catenin signaling axis

Cheng Wang, Ting Jiang, Lingli Zheng, Yang Zheng and Xingxing Xie

European Journal of Pharmacology, 2026, 1021, 178830
DOI: 10.1016/j.ejphar.2026.178830

The role of ferroptosis-related non-coding RNA in liver fibrosis

Guozhu Zhang, Kejia Wu, Xiaobo Jiang, Yuan Gao, Dong Ding, Hao Wang, Chongyuan Yu, Xiaozhong Wang, Naixin Jia and Li Zhu

Front. Cell Dev. Biol., 2024, 12
DOI: 10.3389/fcell.2024.1517401

Modification of MSCs with aHSCs-targeting peptide pPB for enhanced therapeutic efficacy in liver fibrosis

Mengqin Yuan, Zhengrong Yin, Zheng Wang, Zhiyu Xiong, Ping Chen, Lichao Yao, Pingji Liu, Muhua Sun, Kan Shu, Lanjuan Li and Yingan Jiang

Biomaterials, 2025, 321, 123295
DOI: 10.1016/j.biomaterials.2025.123295

Chitosan-decorated silibinin-hyaluronic acid conjugate for enhancing intestinal absorption and improving liver fibrosis

Can Wang, Jia-Jun Cui, Tao Sheng, Shuai Xia, Jia-Min Li and Bing-Feng Zhang

International Journal of Biological Macromolecules, 2025, 320, 146057
DOI: 10.1016/j.ijbiomac.2025.146057

Constructing biomimetic microenvironments for liver regeneration

Yawen Zhu, Wanqi Yang, Zhongxia Wang, Dayu Chen, Jinglin Wang and Haozhen Ren

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03729-9

Immune System and Hepatic Stellate Cells’ Crosstalk in Liver Fibrosis: Pathways and Therapeutic Potential

Wahyu Widowati, Adilah Hafizha Nur Sabrina, Annisa Firdaus Sutendi, Fadhilah Haifa Zahiroh, Aris Muhamad Nurjamil, Teresa Liliana Wargasetia, Ita Margaretha Nainggolan, Rizal Azis, Elham Rismani, Massoud Vosough and Poorani Gurumallesh Prabu

Journal of Immunology Research, 2026, 2026
DOI: 10.1155/jimr/2656395

Network pharmacology and animal experiments reveal the mechanism of action of hydroxysafflower yellow a against liver fibrosis

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu and Jing Yang

South African Journal of Botany, 2026, 190, 179
DOI: 10.1016/j.sajb.2026.01.016

Prominent Imaging for Differentiating Severity of Drug-Induced Liver Injury by an Esterase Activatable Near-Infrared Fluorescent Probe

Hong-Zhen Wang, Yi-Ran Shu, Ying Luo, Dong-Mei Xi, Tian-Bing Ren, Lin Yuan and Xiao-Peng Fan

J. Med. Chem., 2025
DOI: 10.1021/acs.jmedchem.5c03044

GalNAc End‐Capped Poly(β‐amino ester)s with Screened Side Chains for Efficient Gene Delivery

Xinlong Liu, Yimeng Li, Xinhua Liu, Yangyang Huang, Fujun Wang, Jiafeng Li, Yuqi Guo, Xinyuan Zhu, Lijuan Zhu and Chuan Zhang

Small Methods, 2025, 9
DOI: 10.1002/smtd.202401286

Si-Wu-Tang improves liver fibrosis by restoring liver sinusoidal endothelial cell functionality and reducing communication with hepatic stellate cells

Le Wang, Jiaorong Qu, Jianan Li, Xiaoyong Xue, Lingling Qin, Yufei Li, Yuanfeng Dou, Xiaohong Mu and Xiaojiaoyang Li

Chin Med, 2024, 19
DOI: 10.1186/s13020-024-01038-1

Imidazole-Based ALK5 Inhibitor Attenuates TGF-β/Smad-Mediated Hepatic Stellate Cell Activation and Hepatic Fibrogenesis

Si-Qi Wang, Yu-Qing Meng, Yan-Ling Wu, Ji-Xing Nan, Cheng-Hua Jin and Li-Hua Lian

Chem. Res. Toxicol., 2025, 38, 930
DOI: 10.1021/acs.chemrestox.5c00036

Hybrid prodrug-nanoassemblies coated by chitosan exerted antioxidant and anti-inflammatory effect on liver fibrosis

Tao Sheng, Shuai Xia, Jia-Min Li, Ruo-Bin Peng, Ping-Bo Yan and Bing-Feng Zhang

International Journal of Biological Macromolecules, 2026, 339, 149981
DOI: 10.1016/j.ijbiomac.2025.149981

Preclinical Research on Cinnamic Acid Derivatives for the Prevention of Liver Damage: Promising Therapies for Liver Diseases

Liseth Rubí Aldaba-Muruato, Brayan Escalante-Hipólito, Aldo Yoshio Alarcón-López, Pablo A. Martínez-Soriano, Enrique Angeles and José Roberto Macías-Pérez

Biomedicines, 2025, 13, 1094
DOI: 10.3390/biomedicines13051094

Sulfur dioxide-releasing nanomotors improve the therapeutic effect of liver fibrosis by restoring the fenestrae of sinusoids

Lin Chen, Zhengwei Chen, Di Shi, Haifeng Ke, Chun Mao and Mimi Wan

Journal of Colloid and Interface Science, 2025, 692, 137557
DOI: 10.1016/j.jcis.2025.137557

Kanglexin, a new anthraquinone compound, attenuates hepatic fibrosis by regulating the TGF-β/SMADS signaling pathway and glutathione metabolism

Weibing Kou, Qiaohui Liu, Yaping Guo, Ke Zhang, Dahong Yao, Hangyu Wang, Wenyan Chen, Jiacheng Jin, Huili Qi, Xinhui Pan, Pinghua Sun and JinHui Wang

International Immunopharmacology, 2025, 166, 115545
DOI: 10.1016/j.intimp.2025.115545

Three-dimensional cell-based strategies for liver regeneration

DAN GUO, XI XIA and JIAN YANG

BIOCELL, 2024, 48, 1023
DOI: 10.32604/biocell.2024.051095

Mesenchymal Stromal Cell-Derived Extracellular Vesicles for Reversing Hepatic Fibrosis in 3D Liver Spheroids

Giulia Chiabotto, Armina Semnani, Elena Ceccotti, Marco Guenza, Giovanni Camussi and Stefania Bruno

Biomedicines, 2024, 12, 1849
DOI: 10.3390/biomedicines12081849

Acetylbinankadsurin A Decreases Macrophage Glycolysis and Pro-Inflammatory Phenotype Polarization via Inhibiting HIF-1α to Alleviate Hepatic Fibrosis in Mice

Qiang Yao, Wangxia Peng, Huaguan Lu, Yupei Yang, Ziti Rao, Xin Xie, Dan Huang, Wei Wang, Jianye Yan and Jianjun Liu

Molecules, 2025, 30, 4571
DOI: 10.3390/molecules30234571

Metal-phenolic nanoparticles with ROS/pH dual-responsiveness for liver fibrosis therapy via synergistic microenvironment remodeling and metabolic reprogramming

Guangyang Su, Shenen Hu, Lei Zhao, Yi Zhan, Musi Ji, Peier Li, Maierhaba Aihaiti, Xinting Li, Wenqiang Li, Xiaohua Su and Bayaer Nashun

Colloids and Surfaces B: Biointerfaces, 2026, 263, 115595
DOI: 10.1016/j.colsurfb.2026.115595

Nanotechnology-driven biomaterials for chronic liver diseases: Stage-specific strategies for advanced theranostics

Yishui Cai, Tianqi Nie, Xi Luo, Yiqun Wu and Jun Wu

Acta Biomaterialia, 2026, 212, 103
DOI: 10.1016/j.actbio.2026.01.043

Integrating phytochemical analysis and experimental validation of Ziziphus jujuba seed powder and oil to ameliorate CCl4-induced liver fibrosis in sprague dawley rats

Laiba Tanvir, Khurram Afzal, Asad Abbas, Adnan Amjad, Talha Bin Iqbal, Naeem Sarwar, Rameen Naeem, Ayman Furqan, Bipindra Pandey and Chun-Hua Wang

PLoS One, 2026, 21, e0343428
DOI: 10.1371/journal.pone.0343428

Discovery of Marine Highly Congested Polycyclic Isodhilarane-Type Meroterpenoids as Potential Leads for Treating Liver Fibrosis by Activating the HSF1/AMPK Metabolic Axis

Zhongping Jiang, Yue Chen, Shouyuan Wu, Junjie Wang, Feifei Liu, Jin Liu, Congjun Xu, Wanshan Li, Yong Rao and Ling Huang

J. Med. Chem., 2026, 69, 4346
DOI: 10.1021/acs.jmedchem.5c03055

Gut microbiota in hepatic encephalopathy: a 3PM-guided three-tier health strategy

Jing Chen, Mingliao Niu and Longjiang Zhang

EPMA Journal, 2025, 17, 135
DOI: 10.1007/s13167-025-00433-4