Issue 3, 2023

Synthesis of chalcogen-functionalized 4H-chromen-4-ones via cyclization/chalcogenation of alkynyl aryl ketones mediated by Selectfluor®

Abstract

The synthesis of organochalcogen-functionalized chromenones starting from diorganyl dichalcogenides and alkynyl aryl ketones has been developed. Selectfluor® mediates these cyclization/organochalcogenation reaction sequences under mild and open-to-air conditions. The six-membered heterocycles were obtained via a selective 6-endo-dig cyclization compatible with the use of both diorganyl diselenides and disulfides. This synthetic methodology still proved to be versatile to synthesize organochalcogen-substituted thiochromenone and isocromenone derivatives.

Graphical abstract: Synthesis of chalcogen-functionalized 4H-chromen-4-ones via cyclization/chalcogenation of alkynyl aryl ketones mediated by Selectfluor®

Supplementary files

Article information

Article type
Paper
Submitted
13 nov 2022
Accepted
10 dez 2022
First published
12 dez 2022

New J. Chem., 2023,47, 1076-1080

Synthesis of chalcogen-functionalized 4H-chromen-4-ones via cyclization/chalcogenation of alkynyl aryl ketones mediated by Selectfluor®

T. Anjos, E. L. Gutterres, D. A. Barancelli, R. Cargnelutti, B. Godoi, T. Barcellos and R. F. Schumacher, New J. Chem., 2023, 47, 1076 DOI: 10.1039/D2NJ05567H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements