Issue 53, 2023

A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species

Abstract

A nitroreductase (NTR) responsive fluorescent probe with long wavelength fluorescence emission was used to determine the NTR activity of a selection of bacterial species under a range of different bacterial growth conditions ensuring applicability under multiple complex clinical environments, where sensitivity, reaction time, and the detection accuracy were suitable for planktonic cultures and biofilms.

Graphical abstract: A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species

Supplementary files

Article information

Article type
Communication
Submitted
01 fev 2023
Accepted
30 mai 2023
First published
15 jun 2023
This article is Open Access
Creative Commons BY license

Chem. Commun., 2023,59, 8278-8281

A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species

K. Yan, J. E. Gardiner, A. C. Sedgwick, N. Thet, R. A. Heylen, T. D. James, A. T. A. Jenkins and X. He, Chem. Commun., 2023, 59, 8278 DOI: 10.1039/D3CC00462G

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