Issue 18, 2022

Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)

Abstract

Conjugation of maltopentaose to water-soluble homo-poly(sarcosine) induced self-association and formed nanospheres (−150 nm) in water although homo-poly(sarcosine) was water-soluble and did not form any aggregates. Fluorescent probe experiments showed that the spheres were non-ionic glycopeptoid coacervate-like particles with both hydrophobic and hydrophilic domains inside.

Graphical abstract: Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)

Supplementary files

Article information

Article type
Communication
Submitted
07 abr 2022
Accepted
25 jun 2022
First published
27 jun 2022
This article is Open Access
Creative Commons BY license

Nanoscale Adv., 2022,4, 3707-3710

Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine)

Y. Okuno, T. Nishimura, Y. Sasaki and K. Akiyoshi, Nanoscale Adv., 2022, 4, 3707 DOI: 10.1039/D2NA00218C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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