Issue 11, 2021

Recent advances in electrochemically driven radical fluorination and fluoroalkylation

Abstract

Electrochemical fluorination (ECF) refers to the introduction of fluorine-containing moieties into organic molecules under electrochemical conditions. The primary objective of this review is to provide the reader with the highlights of electron-induced radical fluorinations in the past decade, comprising fluorination, difluoromethylation, trifluoromethylation and perfluoroalkylation. Some representative mechanisms are outlined for researchers to gain insight in the basic principles behind this technology.

Graphical abstract: Recent advances in electrochemically driven radical fluorination and fluoroalkylation

Article information

Article type
Review Article
Submitted
03 fev 2021
Accepted
30 mar 2021
First published
31 mar 2021

Org. Chem. Front., 2021,8, 2786-2798

Recent advances in electrochemically driven radical fluorination and fluoroalkylation

Z. Zou, W. Zhang, Y. Wang and Y. Pan, Org. Chem. Front., 2021, 8, 2786 DOI: 10.1039/D1QO00054C

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