Issue 29, 2021

Polysaccharide-reinforced amyloid fibril hydrogels and aerogels

Abstract

β-Lactoglobulin amyloid fibrils are bio-colloids of high interest in many fields (e.g. water purification, cell growth, drug delivery and sensing). While the mechanical properties of pure amyloid fibril gels meet the needs of some applications, mechanical fragility often hinders a wider usage basin. In this work, we present a simple and sustainable approach for reinforcing amyloid fibril hydrogels and aerogels, upon the diffusion of polysaccharides (low-acetylated Gellan Gum and κ-carrageenan) inside their mesh. The formed hybrid materials show enhanced resistance upon compression, without any loss of the exquisite surface reactivity of the amyloid fibrils. The proposed approach can pave the way for designing composite materials that are both highly functional and environmentally friendly.

Graphical abstract: Polysaccharide-reinforced amyloid fibril hydrogels and aerogels

Supplementary files

Article information

Article type
Paper
Submitted
15 mai 2021
Accepted
25 jun 2021
First published
25 jun 2021
This article is Open Access
Creative Commons BY-NC license

Nanoscale, 2021,13, 12534-12545

Polysaccharide-reinforced amyloid fibril hydrogels and aerogels

M. Usuelli, T. Germerdonk, Y. Cao, M. Peydayesh, M. Bagnani, S. Handschin, G. Nyström and R. Mezzenga, Nanoscale, 2021, 13, 12534 DOI: 10.1039/D1NR03133C

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements