Issue 14, 2018

Microfluidics-enabled rational design of immunomagnetic nanomaterials and their shape effect on liquid biopsy

Abstract

Microfluidics brings unique opportunities for the synthesis of nanomaterials toward efficient liquid biopsy. Herein, we developed the microreactor-enabled flow synthesis of immunomagnetic nanomaterials with controllable shapes (sphere, cube, rod, and belt) by simply tuning the flow rates. The particle shape-dependent screening efficiency of circulating tumor cells was first investigated and compared with commercial ferrofluids, providing new insights into the rational design of a particulate system toward the screening and analysis of circulating tumor biomarkers.

Graphical abstract: Microfluidics-enabled rational design of immunomagnetic nanomaterials and their shape effect on liquid biopsy

Supplementary files

Article information

Article type
Communication
Submitted
17 mar 2018
Accepted
11 jun 2018
First published
12 jun 2018

Lab Chip, 2018,18, 1997-2002

Author version available

Microfluidics-enabled rational design of immunomagnetic nanomaterials and their shape effect on liquid biopsy

N. Hao, Y. Nie, T. Shen and J. X. J. Zhang, Lab Chip, 2018, 18, 1997 DOI: 10.1039/C8LC00273H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements