Issue 73, 2018

Activation of C–F bonds α to C–C multiple bonds

Abstract

C–F bond activation has drawn a lot of attention in the past, and the case of C(sp3)–F bonds is particularly interesting as those are the strongest single bonds carbon makes with any other element. This Feature Article aims at highlighting our work and that of others on the successful approaches that led to the activation of such C–F bonds at benzylic, allylic, propargylic and allenylic positions, for both mono- and polyfluorides. We now hope that this will set ground for discussions, contribute to fostering new ideas, and thus help in pushing current frontiers further.

Graphical abstract: Activation of C–F bonds α to C–C multiple bonds

Article information

Article type
Feature Article
Submitted
26 jun 2018
Accepted
07 ago 2018
First published
20 ago 2018

Chem. Commun., 2018,54, 10224-10239

Activation of C–F bonds α to C–C multiple bonds

J. Hamel and J. Paquin, Chem. Commun., 2018, 54, 10224 DOI: 10.1039/C8CC05108A

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