Issue 52, 2016

A new strategy for detecting dopamine in human serum using polymer brushes reinforced with carbon nanotubes

Abstract

Direct detection of dopamine (DA) in serum samples without any type of extraction or pre-treatment has been a great challenge for biomedical analysis. This paper reports the development of a sensor consisting of polymer brushes reinforced with multi-walled carbon nanotubes, that was used to determine levels of dopamine in human blood serum. The structure and morphology of the as-prepared hybrid nanomaterials were characterized and confirmed by scanning electron microscopy and electrochemistry techniques. This methodology employs differential pulse voltammetry to detect dopamine in human serum samples at concentrations ranging from 0.1 μM to 10 μM with an obtained detection limit of 40.5 nmol L−1 (R = 0.996). This sensor provides an inexpensive and easy-to-use device with high degrees of sensitivity and selectivity for monitoring DA in human blood serum samples.

Graphical abstract: A new strategy for detecting dopamine in human serum using polymer brushes reinforced with carbon nanotubes

Article information

Article type
Communication
Submitted
26 fev 2016
Accepted
05 mai 2016
First published
09 mai 2016

RSC Adv., 2016,6, 47134-47137

A new strategy for detecting dopamine in human serum using polymer brushes reinforced with carbon nanotubes

L. C. Recco, B. P. Crulhas, J. P. R. L. L. Parra and V. A. Pedrosa, RSC Adv., 2016, 6, 47134 DOI: 10.1039/C6RA05151K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements